Urgent need for solutions

Antimicrobial Resistance (AMR) is recognised by the World Health Organization (WHO) and many Governments, including Australia, as one of the world’s most pressing global health priorities. If the spread of AMR is not curtailed, new diagnostics and antibiotics not developed, and effective stewardship programs not implemented, the world faces a future where common and treatable infections, which have been effectively treated for the last 80 years, will become life threatening to humans and animals. The O’Neill AMR Report estimated that more people will die from AMR infections than cancer in 2050.

The AMR CRC Program

The Antimicrobial Resistance Cooperative Research Centre (AMR CRC) is currently being developed in partnership between The University of Queensland, Monash University, CSIRO, University of New South Wales, University of Technology Sydney, Government departments, industry partners (including SMEs) and industry bodies. As discussions progress, additional research organisations will be incorporated into the CRC program.

We believe that the AMR CRC will become the pivotal organisation in Australia’s fight to halt AMR’s health and economic burden through a coordinated response. The Research Themes and Education programs will investigate and improve a wide range of human and animal health issues, which will result in co-ordinated and enhanced outcomes for the communities and organisations involved. The CRC will work closely with existing programs to ensure that there is minimal overlap to maximum impact.

AMR CRC ThemesTheme 1: One health

  • Improving animal health outcomes
  • Studying intersection of human health, animal health, agriculture, food and the environment

Theme 2: Infection control and prevention

  • Engineering devices and coatings to prevent infection
  • Detection and surveillance of antibiotic resistance
  • Implementing infection control into practice

Theme 3: Antibiotic development

  • Antibiotic discovery and lead optimisation
  • Pharmacokinetics and pharmacodynamics (PK/PD)
  • Clinical trials of new and marketed antibiotics

Education

  • Student industry placement/training: internships
  • Stewardship and lectures
  • Community outreach programs

Alignment with government priorities

In June 2015, the Australian Government released their first ever National Antimicrobial Resistance (AMR) Strategy 2015–2019, which focused on minimising the development and spread of AMR, and ensuring the continued availability of effective antimicrobials. The Government has continued its interest publishing a Strategy Progress Report in October 2017 and the establishment of an AMR-focused website. The CRC could play a central role in helping make the Australian Government’s AMR strategy a success.

Cooperative Research Centre (CPC) Program

The CRC Program is an Australian government initiative started in 1990 that supports industry-led collaborations between industry, researchers and the community. CRCs are a successful model for linking researchers with industry to focus on research and development towards use and commercialisation.

Industry participants information

The CRC is currently seeking participant involvement from industry partners, industry bodies and Government departments. Participants that have not already registered their interest will be contacted by the CRC Bid Committee and asked about how the AMR CRC can best benefit their organisation, their industry and Australia. Organisations can attend and actively participate in the May Workshops, which will be held in Melbourne, Sydney and Brisbane, or request a face-to-face or videoconference meeting to directly discuss this opportunity. Interested organisations will be asked to sign a non-binding Stage 1 Expression of Interest.

Research provider information

The CRC invites enquiries from research providers that want to be involved with the CRC. As with the Industry Participants, researchers are welcome to attend the Workshops and to directly contact the CRC for further information. The CRC will expect that the research providers sign a non-binding Stage 1 Expression of Interest.

Intellectual Property

The CRC envisages that IP arrangements will be negotiated on an individual project level; however, this will be finalised after discussions with the various stakeholders during May.

Term

The AMR CRC will be seeking a 7 year term with the final quantum of funding to be determined in May.

Bid timeline

Stage 1 Stage 2

April 2018

Release bid prospectus

September 2018

Stage 2 opens for shortlisted bids

May 2018

Bid workshops

October 2018

Prepare full business case

May 2018

Round 20 opens. Finalise research program

November 2018

Full business case due

June 2018

Prepare expression of interest

March 2019

Outcome announced

July 2018

Stage 1 expression of interest submitted

July 2019

If successful, CRC will commence

Bid workshops

Workshop will be held in Melbourne, Sydney and Brisbane in mid-to late May.

Contact

For further information or enquires on the AMR CRC, please contact:

Dr Mark Butler, AMR CRC Bid Manager

Mobile: 042 204 1127 Office: (07) 3346 5042 Email: m.butler5@uq.edu.au