We employ a wide range of techniques to study oocytes, some of which are undertaken by only a handful of labs in the world. We micro-manipulate live oocytes and embryos, undertake mouse IVF and perform oocyte/embryo culture. We undertake post-transcriptional gene silencing in oocytes using morpholinos and siRNAs. We use mouse models of ageing and obesity along with transgenic animals. Through partnership with IVF clinics, we are investigating human oocytes for the first time in Queensland. Our lab is fully equipped with dedicated state-of-the-art microinjection and confocal imaging (Leica TCS SP8) facilities enabling us to undertake long-term time-lapse fluorescence imaging for tracking meiotic maturation and chromosome segregation in living oocytes (as an example, see our recent paper in Nature Communications).