Improving brain outcomes in the growth restricted newborn using placental stem cell treatment

January 2018December 2020

Grant Type:  Project Grant

Start / End Date:  2018 to 2020

Chief investigators: Colditz P, Khosrotehrani K, Wixey J

Associate investigators: Bjorkman ST, Patel J, Chand K

Growth restriction during pregnancy causes impaired development of the fetal brain and poor neurodevelopmental outcomes such as cerebral palsy. Our project is investigating a novel stem cell treatment to protect baby’s brains – using the baby’s own placenta.

Hypothesis: Placental stem cell treatment will improve brain outcomes in the IUGR neonate.

This project aims to: examine the effect of placental stem cell treatment on neuronal injury, inflammation and brain outcomes in the newborn IUGR piglet brain.

Project members

Professor Paul Colditz

Deputy Director
UQ Centre for Clinical Research
Director
Perinatal Research Centre
Group Head, Clinical Neurosciences Laboratory

Dr Julie Wixey

Postdoctoral Research Fellow
UQ Centre for Clinical Research

Dr Tracey Bjorkman

Senior Research Fellow
UQ Centre for Clinical Research

Dr Kirat Chand

Postdoctoral Research Fellow
UQ Centre for Clinical Research
  • Associate Professor Kiarash Khosrotehrani, Professorial Research Fellow, The University of Queensland Diamantina Institute
  • Dr Jatin Patel, Senior ARC DECRA Fellow, The University of Queensland Diamantina Institute