Funding: Metro North Hospital and Health Services

Chief Investigators: Pienaar J, Wixey J, Lai M, Colditz P, Wright I, Oei J.

Small for gestational age (SGA) is a baby that does not grow well inside the womb – this is usually due to fetal growth restriction (FGR). Brain impairment in SGA newborns is a major cause of death and disability worldwide – with no treatments available for these babies. Ibuprofen has been linked to better brain outcomes following its use for heart conditions in preterm babies. We plan a retrospective study of neurodevelopmental outcomes in preterm SGA infants that have or have not received ibuprofen to treat heart conditions. If results suggest benefit, we can progress to a clinical trial of ibuprofen in SGA infants to improve brain outcomes.

Project members

Dr Julie Wixey

Senior Research Fellow
UQ Centre for Clinical Research

Professor Paul Colditz

Perinatal Research Centre
Affiliate Professor
UQ Centre for Clinical Research