The overall objective of this project is to introduce better identification strategies to diagnose anxiety in Parkinson’s disease (PD). Depression will be examined as a secondary arm. The specific aims are: 

  1. to closely examine the clinical presentation of anxiety in PD and subsequently identify subgroups. 
  2. to identify alterations in the human brain automatic processing of complex information (cognitive biases) in anxious PD patients compared with non-anxious. 
  3. to investigate electrophysiological diagnostic markers (measured by electroencephalogram; EEG) for anxiety in PD. 
  4. to investigate saliva markers (eg: cortisol) associated with anxiety in PD (substudy)

Additionally, this study also aims to introduce other studies that include similar assessment criteria and that data can potentially be shared. This is to reduce participant exhaustion of completing repeated questionnaires and assessment interviews, save time and reduce costs. Other studies introduced will be commenced after gaining written informed consent from participants.In addition to collecting data for this study, we also intend to identify participants that are eligible for participation in other PD studies in the Dementia & Neuro Mental Health Research Unit.