In utero aging of fetal tissues signals human parturition via exosomes
Dr. Ramkumar Menon, Associate Professor of Obstetrics and Gynecology, The University of Texas Medical Branch (UTMB) at Galveston, Texas, USA, has been working in the area of Perinatal Biology and Reproductive Immunology for the past 25 years to understand the pathways and mechanisms of spontaneous preterm birth (PTB) and preterm prelabor rupture of the membranes (pPROM). Earlier in his career, Dr. Menon, developed an in vitro organ explant system to determine the response of human fetal membranes in response to various risk factors of PTB and pPROM. This model and its variations are now widely used to understand fetal immune and endocrine responses by many investigators around the globe.upture of the membranes (pPROM).
His work highlights how aging of fetal membranes generate specific signals and how they are propagated between feto-maternal tissues via exosomes. This novel signaling mechanism by exosomes is expected to contribute immensely to our understanding of parturition process at term and preterm.
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UQCCR Seminar Series
The UQ Centre of Clinical Research (UQCCR) Seminars are held fortnightly on Wednesdays from 12 pm - 1 pm (except during school holidays) currently on Zoom. The series features topics in multiple research fields, presented by invited international, interstate and local researchers.