Book Chapters
Hollenbach, Laura L., Pelosi, Emanuele, Margetts, Miranda and Vash-Margita, Alla (2024). Vulvovaginal and Müllerian Anomalies. Nelson Textbook of Pediatrics. (pp. 3347-3354.e1) Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-323-88305-4.00591-5
Pelosi, Emanuele and Koopman, Peter (2017). Development of the testis. Reference module in biomedical sciences. Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-12-801238-3.99854-4
Journal Articles
Marongiu, Mara, Marcia, Loredana, Sbardellati, Andrea, Deiana, Manila, Asunis, Isadora, Pelosi, Emanuele, Coschiera, Andrea, Crobu, Francesca, Loi, Angela, Melis, Emilio, Mostallino, Maria Cristina, Meloni, Alessandra, Cusano, Roberto, Cucca, Francesco, Uda, Manuela and Crisponi, Laura (2026). Evidence for FOXL2 Association with the Tsc1 Regulatory Region in Mice. Biomolecules, 16 (4), 510. doi: 10.3390/biom16040510
Kyei-Barffour, Isaac, Williams, Sarah, Kushawaha, Bhawna and Pelosi, Emanuele (2026). Wnt5a Regulates Embryonic Müllerian Duct Development Through the Non-Canonical Wnt PCP Pathway. Cells, 15 (4) 359, 359-4. doi: 10.3390/cells15040359
Kushawaha, Bhawna and Pelosi, Emanuele (2025). Spotlight on proteases: Roles in ovarian health and disease. Cells, 14 (12) 921, 1-31. doi: 10.3390/cells14120921
Kushawaha, Bhawna, Rem, Tial T. and Pelosi, Emanuele (2025). Harnessing microbiome, bacterial extracellular vesicle, and artificial intelligence for polycystic ovary syndrome diagnosis and management. Biomolecules, 15 (6) 834, 1-25. doi: 10.3390/biom15060834
Kushawaha, Bhawna, Yadav, Rajkumar, Garg, Satish Kumar and Pelosi, Emanuele (2025). The impact of mercury exposure on male reproduction: mechanistic insights. Journal of Trace Elements in Medicine and Biology, 87 127598, 1-10. doi: 10.1016/j.jtemb.2025.127598
Bhamidipaty-Pelosi, Surya, Kyei-Barffour, Isaac, Volpert, Marianna, O'Neill, Nora, Grimshaw, Alyssa, Eriksson, Lars, Vash-Margita, Alla and Pelosi, Emanuele (2024). Müllerian anomalies and endometriosis: associations and phenotypic variations. Reproductive Biology and Endocrinology, 22 (1) 157, 157. doi: 10.1186/s12958-024-01336-1
Godbole, Nihar, Quinn, Alexander, Carrion, Flavio, Pelosi, Emanuele and Salomon, Carlos (2023). Extracellular vesicles as a potential delivery platform for CRISPR-Cas based therapy in epithelial ovarian cancer. Seminars in Cancer Biology, 96, 64-81. doi: 10.1016/j.semcancer.2023.10.002
Thomson, Ella, Tran, Minh, Robevska, Gorjana, Ayers, Katie, van der Bergen, Jocelyn, Bhaskaran, Prarthna Gopalakrishnan, Haan, Eric, Cereghini, Silvia, Vash-Margita, Alla, Margetts, Miranda, Hensley, Alison, Nguyen, Quan, Sinclair, Andrew, Koopman, Peter and Pelosi, Emanuele (2023). Functional genomics analysis identifies loss of HNF1B function as a cause of Mayer-Rokitansky-Küster-Hauser syndrome. Human Molecular Genetics, 32 (6), 1032-1047. doi: 10.1093/hmg/ddac262
Chen, H. Alexander, Grimshaw, Alyssa A., Taylor-Giorlando, Melissa, Vijayakumar, Pavithra, Li, Dan, Margetts, Miranda, Pelosi, Emanuele and Vash-Margita, Alla (2023). Ovarian absence: a systematic literature review and case series report. Journal of Ovarian Research, 16 (1) 13, 13. doi: 10.1186/s13048-022-01090-1
Zhao, Liang, Thomson, Ella, Ng, Ee T., Longmuss, Enya, Svingen, Terje, Bagheri-Fam, Stefan, Quinn, Alexander, Harley, Vincent R., Harrison, Leonard C., Pelosi, Emanuele and Koopman, Peter (2022). Functional analysis of Mmd2 and related PAQR genes during sex determination in mice. Sexual Development, 16 (4), 1-13. doi: 10.1159/000522668
Marongiu, Mara, Crisponi, Laura, Uda, Manuela and Pelosi, Emanuele (2022). Editorial: Female infertility: Genetics of reproductive ageing, menopause and primary ovarian insufficiency. Frontiers in Genetics, 13 839758, 839758. doi: 10.3389/fgene.2022.839758
Thomson, Ella, Zhao, Liang, Chen, Yen‐Shan, Longmuss, Enya, Ng, Ee Ting, Sreenivasan, Rajini, Croft, Brittany, Song, Xin, Sinclair, Andrew, Weiss, Michael, Koopman, Peter and Pelosi, Emanuele (2022). Generation and mutational analysis of a transgenic mouse model of human
SRY. Human Mutation, 43 (3), 362-379. doi: 10.1002/humu.24318
Kyei-Barffour, Isaac, Margetts, Miranda, Vash-Margita, Alla and Pelosi, Emanuele (2021). The embryological landscape of mayer-rokitansky-kuster-hauser syndrome: Genetics and environmental factors. Yale Journal of Biology and Medicine, 94 (4), 657-672.
Croft, Brittany, Ohnesorg, Thomas, Hewitt, Jacqueline, Bowles, Josephine, Quinn, Alexander, Tan, Jacqueline, Corbin, Vincent, Pelosi, Emanuele, van den Bergen, Jocelyn, Sreenivasan, Rajini, Knarston, Ingrid, Robevska, Gorjana, Vu, Dung Chi, Hutson, John, Harley, Vincent, Ayers, Katie, Koopman, Peter and Sinclair, Andrew (2019). Author Correction: Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9. Nature Communications, 10 (1) 3351, 3351. doi: 10.1038/s41467-019-11310-w
Croft, Brittany, Ohnesorg, Thomas, Hewitt, Jacky, Bowles, Josephine, Quinn, Alexander, Tan, Jacqueline, Corbin, Vincent, Pelosi, Emanuele, van den Bergen, Jocelyn, Sreenivasan, Rajini, Knarston, Ingrid, Robevska, Gorjana, Vu, Dung Chi, Hutson, John, Harley, Vincent, Ayers, Katie, Koopman, Peter and Sinclair, Andrew (2018). Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9. Nature Communications, 9 (1) 5319, 5319. doi: 10.1038/s41467-018-07784-9
Backhouse, Brendan, Hanna, Chloe, Robevska, Gorjana, van den Bergen, Jocelyn, Pelosi, Emanuele, Simons, Cas, Koopman, Peter, Juniarto, A. Zulfa, Grover, Sonia, Faradz, Sultana, Sinclair, Andrew, Ayers, Katie and Tan, Tiong Y. (2018). Identification of candidate genes for Mayer-Rokitansky-Küster-Hauser syndrome using genomic approaches. Sexual Development, 13 (1), 26-34. doi: 10.1159/000494896
D'Ignazio, Laura, Michel, Marc, Beyer, Melissa, Thompson, Kassimier, Forabosco, Antonino, Schlessinger, David and Pelosi, Emanuele (2018). Lhx8 ablation leads to massive autophagy of mouse oocytes associated with DNA damage. Biology of Reproduction, 98 (4), 532-542. doi: 10.1093/biolre/iox184
Gustin, Sonja E., Hogg, Kirsten, Stringer, Jessica M., Rastetter, Raphael H., Pelosi, Emanuele, Miles, Denise C., Sinclair, Andrew H., Wilhelm, Dagmar and Western, Patrick S. (2016). WNT/β-catenin and p27/FOXL2 differentially regulate supporting cell proliferation in the developing ovary. Developmental Biology, 412 (2), 250-260. doi: 10.1016/j.ydbio.2016.02.024
Pelosi, Emanuele, Forabosco, Antonino and Schlessinger, David (2015). Genetics of the ovarian reserve. Frontiers in Genetics, 6 (OCT) 308. doi: 10.3389/fgene.2015.00308
Marongiu, Mara, Marcia, Loredana, Pelosi, Emanuele, Lovicu, Mario, Deiana, Manila, Zhang, Yonqing, Puddu, Alessandro, Loi, Angela, Uda, Manuela, Forabosco, Antonino, Schlessinger, David and Crisponi, Laura (2015). FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice. BMC Developmental Biology, 15 (1) 27. doi: 10.1186/s12861-015-0072-y
Pelosi, Emanuele, Simonsick, Eleanor, Forabosco, Antonino, Elias Garcia-Ortiz, Jose and Schlessinger, David (2015). Dynamics of the ovarian reserve and impact of genetic and epidemiological factors on age of menopause. Biology of Reproduction, 92 (5) 127. doi: 10.1095/biolreprod.114.127381
Takasawa, Kei, Kashimada, Kenichi, Pelosi, Emanuele, Takagi, Masatoshi, Morio, Tomohiro, Asahara, Hiroshi, Schlessinger, David, Mizutani, Shuki and Koopman, Peter (2014). FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice. The FASEB Journal, Early Edition (5), 1-9. doi: 10.1096/fj.13-246108
Pelosi, Emanuele, Omari, Shakib, Michel, Marc, Ding, Jun, Amano, Tomokazu, Forabosco, Antonino, Schlessinger, David and Ottolenghi, Chris (2013). Constitutively active Foxo3 in oocytes preserves ovarian reserve in mice. Nature Communications, 4. doi: 10.1038/ncomms2861
Pelosi, Emanuele (2011). Delaying pregnancy. Anatomy and Physiology: Current Research. doi: 10.4172/2161-0940.1000e110
Kashimada, Kenichi, Svingen, Terje, Feng, Chun-Wei, Pelosi, Emanuele, Bagheri-Fam, Stefan, Harley, Vincent R., Schlessinger, David, Bowles, Josephine and Koopman, Peter (2011). Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice. The FASEB Journal, 25 (10), 3561-3569. doi: 10.1096/fj.11-184333
Justice, Nicholas J., Blount, Amy L., Pelosi, Emanuele, Schlessinger, David, Vale, Wylie and Bilezikjian, Louise M. (2011). Impaired FSH beta expression in the pituitaries of Foxl2 mutant animals. Molecular Endocrinology, 25 (8), 1404-1415. doi: 10.1210/me.2011-0093
Zhang, Yujin, Kao, Winston W. -Y., Pelosi, Emanuele, Schlessinger, David and Liu, Chia-Yang (2011). Notch gain of function in mouse periocular mesenchyme downregulates FoxL2 and impairs eyelid levator muscle formation, leading to congenital blepharophimosis. Journal of Cell Science, 124 (15), 2561-2572. doi: 10.1242/jcs.085001
Kashimada, Kenichi, Pelosi, Emanuele, Chen, Huijun, Schlessinger, David, Wilhelm, Dagmar and Koopman, Peter (2011). FOXL2 and BMP2 act cooperatively to regulate Follistatin gene expression during ovarian development. Endocrinology, 152 (1), 272-280. doi: 10.1210/en.2010-0636
Pelosi, Emanuele, Forabosco, Antonino and Schlessinger, David (2011). Germ cell formation from embryonic stem cells and the use of somatic cell nuclei in oocytes. Reproductive Science, 1221 (1), 18-26. doi: 10.1111/j.1749-6632.2011.05982.x
Garcia-Ortiz, José, Pelosi, Emanuele, Omari, Shakib, Nedorezov, Timur, Piao, Yulan, Karmazin, Jesse, Uda, Manuela, Cao, Antonio, Cole, Steve W, Forabosco, Antonino, Schlessinger, David and Ottolenghi, Chris (2009). Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Developmental Biology, 9 (1) 36, 36. doi: 10.1186/1471-213x-9-36
Ottolenghi, Chris, Pelosi, Emanuele, Tran, Joseph, Colombino, Maria, Douglass, Eric, Nedorezov, Timur, Cao, Antonio, Forabosco, Antonino and Schlessinger, David (2007). Loss of Wnt4 and Foxl2 leads to female-to-male sex reversal extending to germ cells. Human Molecular Genetics, 16 (23), 2795-2804. doi: 10.1093/hmg/ddm235
Stirpe, Florenzo, Bolognesi, Andrea, Bortolotti, Massimo, Farini, Valentina, Lubelli, Chiara, Pelosi, Emanuele, Polito, Letizia, Dozza, Barbara, Strocchi, Paola, Chambery, Angela, Parente, Augusto and Barbieri, Luigi (2007). Characterization of highly toxic type 2 ribosome-inactivating proteins from Adenia lanceolata and Adenia stenodactyla (Passifloraceae). Toxicon, 50 (1), 94-105. doi: 10.1016/j.toxicon.2007.02.020
Barbieri Luigi, Polito, Letizia, Bolognesi, Aandrea, Ciani, Marialibera, Pelosi, Emanuele, Farini, Valentina, Jha, Ajay K., Sharma, Neelam, Vivanco, Jorge M., Chambery, Angela, Parente, Augusto and Stirpe, Fiorenzo (2006). Ribosome-inactivating proteins in edible plants and purification and characterization of a new ribosome-inactivating protein from Cucurbita moschata. Biochimica et Biophysica Acta, 1760 (5), 783-792. doi: 10.1016/j.bbagen.2006.01.002
Pelosi, Emanuele, Lubelli, Chiara, Polito, Letizia, Barbieri, Luigi, Bolognesi, Andrea and Stirpe, Fiorenzo (2005). Ribosome-inactivating proteins and other lectins from Adenia (Passifloraceae). Toxicon: an interdisciplinary journal on the toxins derived from animals, plants and microorganisms, 46 (6), 658-63. doi: 10.1016/j.toxicon.2005.07.008
Bulletti, Carlo, DeZiegler, Dominique, Stefanetti, Marco, Cicinelli, Ettore, Pelosi, Emanuele and Flamigni, Carlo (2001). Endometriosis: absence of recurrence in patients after endometrial ablation. Human Reproduction, 16 (12), 2676-9. doi: 10.1093/humrep/16.12.2676
Conference Papers
Chen, Yen-Shan, Thomson, Ella, Pelosi, Emanuele and Weiss, Michael A. (2024). Human Sex Determination: SRY Length Regulates Its Cellular Stability And Hence The Robustness Of Testis Differentiation. ENDO 2024 Annual Meeting of the Endocrine Society, Boston, MA United States, 1-4 June 2024. The Endocrine Society. doi: 10.1210/jendso/bvae163.1609
MacCarter, Bethany, Margetts, Miranda, Vash-Margita, Alla, Carter, Benjamin, Hedges, David and Pelosi, Emanuele (2023). Challenges to Access to Care in the Mountain West Region of the United States for Patients with Congenital Uterine Anomalies: Results from a Pilot Study. NASPAG 37TH Annual Clinical Research Meeting, Nashville, TN United States, 24-26 March 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.jpag.2023.01.143
Saleh, Farrah L., Vash-Margita, Alla, Margetts, Miranda and Pelosi, Emanuele (2023). Assessing Clinical Care Experiences of Patients with Congenital Uterine Anomalies: a Pilot Study. NASPAG 37th Annual Clinical Research Meeting, Nashville, TN United States, 24-26 March 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.jpag.2023.01.101
Pelosi, Emanuele, Margetts, Miranda and Vash-Margita, Alla (2021). A novel mouse model of retrograde menstruation for the study of endometriosis. Scientific Congress of the American Society for Reproductive Medicine, Baltimore, MD, United States, 17-20 October 2021. Philadelphia, PA, United States: Elsevier.
Takasawa, Kei, Pelosi, Emanuele, Takagi, Masatoshi, Morio, Tomohiro, Asahara, Hiroshi, Schlessinger, David, Mizutani, Shuki, Koopman, Peter and Kashimada, Kenichi (2014). FOXL2 Transcriptionally Represses Sf1 Expression By Antagonizing WT1 during Ovarian Development in Mice. WASHINGTON: ENDOCRINE SOC.
Palini, S., Zolla, L., De Stefani, S., Scala, V., D'Alessandro, A., Polli, V., Rocchi, P., Tiezzi, A., Pelosi, E., Dusi, L. and Bulletti, C. (2011). Eomics in blastocoele. 27th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology, Stockholm Sweden, Jul 03-06, 2011. OXFORD: OXFORD UNIV PRESS.
Palini, S., De Stefani, S., Scala, V., Benedetti, S., Tagliamonte, M. C., Catalani, S., Primiterra M. A., Polli, V., Rocchi, P., Tiezzi, A., Donati, L., Pelosi, E., Canestrari, F. and Bulletti, C. (2011). Analysis of the correlation between semen parameters and the levels of retinol, tocopherol and carotenoids in human seminal plasma and blood. 27th Annual Meeting of the European Society of Human Reproduction and Embryology, Stockholm, Sweden, 3-6 July 2011. OXFORD: OXFORD UNIV PRESS.
Schlessinger, David, Garcia-Ortiz, José-Elias, Forabosco, Antonino, Uda, Manuela, Crisponi, Laura and Pelosi, Emanuele (2010). Determination and stability of gonadal sex. XXth North American Testis Workshop, Philadelphia, PA, United States, 1 - 4 April 2009. Schaumburg, IL, United States: American Society of Andrology. doi: 10.2164/jandrol.109.008201
Newspaper Article
Pelosi, Emanuele (2018, 03 19). Unusual conditions: MRKH syndrome, when a woman’s uterus never develops The Conversation