Dr Adam Stewart
PhD student
UQ Centre for Clinical Research
Researcher biography
Adam G. Stewart, BBiomedSci, MBBS (Hons), MPHTM
Dr. Adam Stewart is an Infectious Diseases & Microbiology Registrar at Royal Brisbane & Women's Hospital and a Medical Research Fellow at University of Queensland Centre for Clinical Research (UQCCR).
Adam is currently undertaking a PhD under the supervision of Professor David Paterson on an international multicentre randomised clinical trial comparing ceftolozane-tazobactam versus meropenem for the definitive treatment of bloodstream infection due to ESBL and AmpC producing Enterobacterales (MERINO 3). Adam was recently successful in being awarded a Queensland Health Junior Doctor Research Fellowship and has research interests which include pragmatic clinical trials, novel antimicrobials, microbiome analysis, antibiotic susceptibility testing, and infections in immunocompromised hosts including fungal infections.
Adam has been awarded numerous awards and prizes, such as the RACP Trainee Research Award, Avant Doctor-in-Training Research Scholarship and an ECCMID Travel Grant. He has been invited to speak at national and international conferences, has published over 20 peer-reviewed manuscripts and has been a peer reviewer for journals such as Clinical Infectious Diseases, Journal of Antimicrobial Chemotherapy, Journal of Infection and International Journal of Antimicrobial Agents.
Journal Articles
Stewart, Adam G., Isler, Burcu, Simos, Peter, Farquhar, Drew, George, Narelle, Golmayo, Mila and Heney, Claire (2023). Aspergillus Species Causing Invasive Fungal Disease in Queensland, Australia. Mycopathologia, 1-9. doi: 10.1007/s11046-023-00713-5
Divithotewala, Chandima, Sweeney, Emma L., Burke, Andrew, Graves, Bianca, Stewart, Adam, Whiley, David, Heney, Claire, Hopkins, Peter M. and Chambers, Daniel C. (2023). Mycoplasma hominis and Ureaplasma urealyticum infections in the immediate post-lung transplant period: A case series and literature review. Transplant Infectious Disease e14058, 1-7. doi: 10.1111/tid.14058
Stewart, Adam G., Roberts, Jason A., Forde, Brian M., Bergh, Haakon, Kidd, Timothy J., Wright, Hugh and Harris, Patrick N. A. (2023). Treatment Failure Due to Adaptive Resistance Mechanisms in a Severe and Complicated Bloodstream Infection Due to . Microbial Drug Resistance, 29 (4), 145-149. doi: 10.1089/mdr.2022.0179
Stewart, Adam, Schlebusch, Sanmarie, Vlack, Susan, McMahon, Jamie, Sullivan, Mitchell, Pyke, Alyssa and Hajkowicz, Krispin (2023). First case of mpox diagnosed in Queensland, Australia: clinical and molecular aspects. Medical Journal of Australia, 218 (4), 157-159. doi: 10.5694/mja2.51842
Parkes-Smith, Jill, Bauer, Michelle J., Bergh, Haakon, Eidan, Anthony, Forde, Brian M., Hilton, John, Kidd, Timothy J., Schmidt, Campbell, Stewart, Adam G. and Harris, Patrick N. A. (2022). Case report: a fatal case of Aspergillus felis infection in an immunocompetent host. Access Microbiology, 4 (11), acmi000453. doi: 10.1099/acmi.0.000453
Laupland, Kevin B., Harris, Patrick N. A., Stewart, Adam G., Edwards, Felicity and Paterson, David L. (2022). Culture-based determinants and outcome of Staphylococcus aureus bloodstream infections. Diagnostic Microbiology and Infectious Disease, 104 (3) 115772, 1-5. doi: 10.1016/j.diagmicrobio.2022.115772
Madden, Danielle E., McCarthy, Kate L., Bell, Scott C., Olagoke, Olusola, Baird, Timothy, Neill, Jane, Ramsay, Kay A., Kidd, Timothy J., Stewart, Adam G., Subedi, Shradha, Choong, Keat, Fraser, Tamieka A., Sarovich, Derek S. and Price, Erin P. (2022). Rapid fluoroquinolone resistance detection in Pseudomonas aeruginosa using mismatch amplification mutation assay-based real-time PCR. Journal of Medical Microbiology, 71 (10) 001593, 1-10. doi: 10.1099/jmm.0.001593
Tariq, Arsalan, Stewart, Adam G., Desai, Devang J., Britton, Sumudu, Dunglison, Nigel, Esler, Rachel and Roberts, Matthew J. (2022). Periurethral abscess etiology, risk factors, treatment options, and outcomes: A systematic review. Current Urology, Publish Ahead of Print (2), 100-108. doi: 10.1097/cu9.0000000000000159
Stewart, Adam G., Isler, Burcu and Paterson, David L. (2022). An Australian perspective on antimicrobial stewardship programs and transplantation. Transplant Infectious Disease, 24 (5) e13912, 1-4. doi: 10.1111/tid.13912
Isler, Burcu, Vatansever, Cansel, Özer, Berna, Çınar, Güle, Aslan, Abdullah Tarık, Stewart, Adam, Simos, Peter, Falconer, Caitlin, Bauer, Michelle J., Forde, Brian, Harris, Patrick, Şimşek, Funda, Tülek, Necla, Demirkaya, Hamiyet, Menekşe, Şirin, Akalin, Halis, Balkan, İlker İnanç, Aydın, Mehtap, Tigen, Elif Tükenmez, Demir, Safiye Koçulu, Kapmaz, Mahir, Keske, Şiran, Doğan, Özlem, Arabacı, Çiğdem, Yağcı, Serap, Hazırolan, Gülşen, Bakır, Veli Oğuzalp, Gönen, Mehmet, Saltoğlu, Neşe ... Can, Füsun (2022). Comparison of ceftazidime-avibactam susceptibility testing methods against OXA-48-like carrying Klebsiella blood stream isolates. Diagnostic Microbiology and Infectious Disease, 104 (1) 115745, 1-4. doi: 10.1016/j.diagmicrobio.2022.115745
Laupland, Kevin B., Paterson, David L., Stewart, Adam G., Edwards, Felicity and Harris, Patrick N. A. (2022). Sphingomonas paucimobilis bloodstream infection is a predominantly community-onset disease with significant lethality. International Journal of Infectious Diseases, 119, 172-177. doi: 10.1016/j.ijid.2022.03.060
Balcerek, Matthew I., Stewart, Adam G., Chapman, Paul and Lazarus, Syndia (2022). Reducing the off-target endocrinologic adverse effects of azole antifungals – can it be done?. International Journal of Antimicrobial Agents, 59 (5) 106587, 106587. doi: 10.1016/j.ijantimicag.2022.106587
Tariq, Arsalan, Stewart, Adam G., Teloken, Patrick E., Dunglison, Nigel T., Martin, Benjamin F. and Roberts, Matthew J. (2022). Painless penile periurethral polymicrobial abscess causing urinary retention. Urology Case Reports, 42 102037, 1-3. doi: 10.1016/j.eucr.2022.102037
Laupland, Kevin B., Paterson, David L., Edwards, Felicity, Stewart, Adam G. and Harris, Patrick N. A. (2022). Morganella morganii, an emerging cause of bloodstream infections. Microbiology Spectrum, 10 (3), e0056922. doi: 10.1128/spectrum.00569-22
Simos, Peter A., Holland, David J., Stewart, Adam, Isler, Burcu, Hughes, Ian, Price, Nathan, Henderson, Andrew and Alcorn, Kylie (2022). Clinical prediction scores and the utility of time to blood culture positivity in stratifying the risk of infective endocarditis in Staphylococcus aureus bacteraemia. Journal of Antimicrobial Chemotherapy, 77 (7), 2003-2010. doi: 10.1093/jac/dkac129
Laupland, Kevin B, Stewart, Adam G, Edwards, Felicity, Paterson, David L, Coulter, Sonali, Heney, Claire, George, Narelle and Harris, Patrick (2022). Shewanella spp. bloodstream infections in Queensland, Australia. Emerging Infectious Diseases, 28 (4), 701-706. doi: 10.3201/eid2804.212193
Christensen, Jacob, O'Callaghan, Kevin, Sinclair, Holly, Hawke, Kate, Love, Amanda, Hajkowicz, Krispin and Stewart, Adam G. (2022). Risk factors, treatment and outcomes of subacute thyroiditis secondary to COVID ‐19: a systematic review. Internal Medicine Journal, 52 (4) imj.15432, 522-529. doi: 10.1111/imj.15432
Simos, Peter and Stewart, Adam G. (2022). Sexually acquired reactive arthritis secondary to macrolide‐resistant Mycoplasma genitalium urethritis. Internal Medicine Journal, 52 (2), 332-333. doi: 10.1111/imj.15684
Laupland, Kevin B., Stewart, Adam G., Edwards, Felicity, Harris, Patrick, Heney, Claire, George, Narelle, Coulter, Sonali and Paterson, David L. (2022). Pasteurella species bloodstream infections in Queensland, Australia, 2000–2019. European Journal of Clinical Microbiology and Infectious Diseases, 41 (4), 609-614. doi: 10.1007/s10096-022-04411-w
Stewart, Adam G, Henderson, Andrew, Bauer, Michelle J, Paterson, David L and Harris, Patrick N A (2021). Activity of temocillin against third-generation cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae bloodstream isolates from a clinical trial. JAC-Antimicrobial Resistance, 4 (1) dlab192, dlab192. doi: 10.1093/jacamr/dlab192
Henderson, Andrew, Bursle, Evan, Stewart, Adam, Harris, Patrick N. A., Paterson, David, Chatfield, Mark D., Paul, Mical, Dickstein, Yaakov, Rodriguez-Baño, Jesus, Turnidge, John D. and Kahlmeter, Gunnar (2021). A systematic review of antimicrobial susceptibility testing as a tool in clinical trials assessing antimicrobials against infections due to Gram negative pathogens. Intended category: systematic review. Clinical Microbiology and Infection, 27 (12), 1746-1753. doi: 10.1016/j.cmi.2021.03.019
Stewart, Adam G., Harris, Patrick N. A., Chatfield, Mark D., Littleford, Roberta and Paterson, David L. (2021). Ceftolozane-tazobactam versus meropenem for definitive treatment of bloodstream infection due to extended-spectrum beta-lactamase (ESBL) and AmpC-producing Enterobacterales (“MERINO-3”): study protocol for a multicentre, open-label randomised non-inferiority trial. Trials, 22 (1) 301, 301. doi: 10.1186/s13063-021-05206-8
Stewart, Adam G. and Stewart, Alexandra G. A. (2021). An update on the laboratory diagnosis of Rickettsia spp. infection. Pathogens, 10 (10) 1319, 1319. doi: 10.3390/pathogens10101319
Isler, Burcu, Harris, Patrick, Stewart, Adam G. and Paterson, David L. (2021). An update on cefepime and its future role in combination with novel β-lactamase inhibitors for MDR Enterobacterales and Pseudomonas aeruginosa–—authors’ response. Journal of Antimicrobial Chemotherapy, 76 (12), 3327-3328. doi: 10.1093/jac/dkab366
Stewart, Adam G., Sinclair, Holly, Chapman, Paul, Baboolal, Keshwar, Barber, Bridget E. and Townsend, Shane (2021). Cryptococcus neoformans
infection as a cause of severe hyperammonaemia and encephalopathy. Internal Medicine Journal, 51 (10), 1750-1751. doi: 10.1111/imj.15516
Stewart, Adam G., Paterson, David L., Young, Barnaby, Lye, David C, Davis, Joshua S., Schneider, Kellie, Yilmaz, Mesut, Dinleyici, Rumeysa, Runnegar, Naomi, Henderson, Andrew, Archuleta, Sophia, Kalimuddin, Shirin, Forde, Brian M., Chatfield, Mark D., Bauer, Michelle J., Lipman, Jeffrey, Harris-Brown, Tiffany, Harris, Patrick N. A. and for the MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN) (2021). Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections caused by AmpC beta-lactamase producing Enterobacter spp., Citrobacter freundii, Morganella morganii, Providencia spp., or Serratia marcescens: a pilot multi-center randomized controlled trial (MERINO-2). Open Forum Infectious Diseases, 8 (8) ofab387, ofab387. doi: 10.1093/ofid/ofab387
Stewart, Adam G., Baidya, Shoma, Daly, James and Scott, Ashleigh P. (2021). Prolonged granulocyte transfusions sourced from buffy coats used to treat Aspergillus spp. infection in chronic granulomatous disease. Pathology, 54 (3), 358-361. doi: 10.1016/j.pathol.2021.05.098
Stewart, Adam G., Cottrell, Kyra, Henderson, Andrew, Vemuri, Kanthi, Bauer, Michelle J., Paterson, David L. and Harris, Patrick N. A. (2021). In vitro activity of Cefotetan against ESBL-producing Escherichia coli and Klebsiella pneumoniae bloodstream isolates from the MERINO Trial. Microbiology Spectrum, 9 (1) e00226-21, 1-6. doi: 10.1128/spectrum.00226-21
Peri, Anna Maria, Stewart, Adam, Hume, Anna, Irwin, Adam and Harris, Patrick N A (2021). New microbiological techniques for the diagnosis of bacterial infections and sepsis in ICU including point of care. Current Infectious Disease Reports, 23 (8) 12, 12. doi: 10.1007/s11908-021-00755-0
Stewart, Adam G., Satlin, Michael J., Schlebusch, Sanmarié, Isler, Burcu, Forde, Brian M., Paterson, David L. and Harris, Patrick N. A. (2021). Completing the picture - capturing the resistome in antibiotic clinical trials. Clinical Infectious Diseases, 72 (12), e1122-e1129. doi: 10.1093/cid/ciaa1877
Chung, Joseph, McCarthy, Kate L., Redmond, Andrew, Butler, Jason, Scott, Ashleigh P. and Stewart, Adam G. (2021). Listeria monocytogenes brain abscess as a late complication of allogeneic haemopoietic stem cell transplantation. Internal Medicine Journal, 51 (6), 1005-1006. doi: 10.1111/imj.15356
Stewart, A. G., Price, E. P., Schabacker, K., Birikmen, M., Harris, P. N. A., Choong, K., Subedi, S. and Sarovich, D. S. (2021). Molecular epidemiology of third-generation cephalosporin-resistant Enterobacteriaceae in Southeast Queensland, Australia. Antimicrobial Agents and Chemotherapy, 65 (6) e00130-21, 1-13. doi: 10.1128/AAC.00130-21
Stewart, Adam G. and Lane, Steven (2021). Just as good but better tolerated: posaconazole as first-line therapy for invasive aspergillosis. The Hematologist, 18 (3).
Stewart, Adam G. and Paterson, David L. (2021). How urgent is the need for new antifungals?. Expert Opinion on Pharmacotherapy, 22 (14), 1-14. doi: 10.1080/14656566.2021.1935868
Stewart, Adam G. and Henden, Andrea S. (2021). Infectious complications of CAR T-cell therapy: a clinical update. Therapeutic Advances in Infectious Disease, 8 204993612110367, 1-11. doi: 10.1177/20499361211036773
Isler, Burcu, Harris, Patrick, Stewart, Adam G. and Paterson, David L. (2020). An update on cefepime and its future role in combination with novel β-lactamase inhibitors for MDR Enterobacterales and Pseudomonas aeruginosa. The Journal of Antimicrobial Chemotherapy, 76 (3), 550-560. doi: 10.1093/jac/dkaa511
Isler, Burcu, Kidd, Timothy J., Stewart, Adam G., Harris, Patrick and Paterson, David L. (2020). Achromobacter infections and treatment options. Antimicrobial Agents and Chemotherapy, 64 (11) e01025, 1-16. doi: 10.1128/aac.01025-20
Isler, Burcu, Ezure, Yukiko, García-Fogeda Romero, Jose Luis, Harris, Patrick, Stewart, Adam G. and Paterson, David L. (2020). Is ceftazidime/avibactam an option for serious infections due to ESBL and AmpC producing Enterobacterales?: a systematic review and meta-analysis. Antimicrobial Agents and Chemotherapy, 65 (1) e01052-20. doi: 10.1128/AAC.01052-20
Stewart, Adam G., Burnard, Delaney, Sowden, David and McMillan, David (2020). Whole genome sequencing for antimicrobial resistance mechanisms, virulence factors and clonality in invasive Streptococcus agalactiae blood culture isolates recovered in Australia. Pathology, 52 (6), 694-699. doi: 10.1016/j.pathol.2020.06.006
Stewart, Adam G., Harris, Patrick N. A., Henderson, Andrew, Schembri, Mark A. and Paterson, David L. (2020). Oral cephalosporin and β-lactamase inhibitor combinations for ESBL-producing Enterobacteriaceae urinary tract infections. Journal of Antimicrobial Chemotherapy, 75 (9), 2384-2393. doi: 10.1093/jac/dkaa183
Paterson, David L., Isler, Burcu and Stewart, Adam (2020). New treatment options for multiresistant gram negatives. Current Opinion in Infectious Diseases, 33 (2), 214-223. doi: 10.1097/QCO.0000000000000627
McNamara, John F., Avent, Minyon, Stewart, Adam, Kwan, Christopher and Paterson, David L. (2020). Evaluation of quick sequential organ failure assessment and systemic inflammatory response syndrome in patients with gram negative bloodstream infection. Infection, Disease and Health, 25 (3), 151-157. doi: 10.1016/j.idh.2020.01.003
Stewart, Adam G. and Wright, Hugh (2020). Initiating tuberculosis treatment at end of life – Balancing patient and infection control interests. Infection, Disease and Health, 25 (4), 283-285. doi: 10.1016/j.idh.2020.05.009
Stewart, Adam G, Harris, Patrick N A, Chatfield, Mark, Evans, Scott R, van Duin, David and Paterson, David L (2019). Modern clinician-initiated clinical trials to determine optimal therapy for multi-drug resistant Gram-negative infections. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71 (2), 433-439. doi: 10.1093/cid/ciz1132
Stewart, Adam G., Broom, Jennifer, Sowden, David and Hollett, Peter (2019). Acute kidney injury in acute Q fever. Internal Medicine Journal, 49 (10), 1326-1329. doi: 10.1111/imj.14447
Stewart, Adam, Sowden, David, Sloss, Andrew and Broom, Jennifer (2019). Inflammatory bowel disease masquerading as traveller's diarrhoea. Internal Medicine Journal, 49 (6), 789-791. doi: 10.1111/imj.14311
Stewart, Adam, Wright, Hugh and Hajkowicz, Krispin (2019). The rise and rise of antimicrobial resistance in Gram-negative bacteria. Microbiology Australia, 40 (2), 62-65. doi: 10.1071/MA19018
Stewart, Adam (2019). Disseminated Mycobacterium intracellulare from a deep cutaneous infection. International journal of mycobacteriology, 8 (1), 98-100. doi: 10.4103/ijmy.ijmy_17_19
Stewart, Adam, Sowden, David, Caffery, Michael, Bint, Michael and Broom, Jennifer (2019). Rhodococcus equi infection: a diverse spectrum of disease. IDCases, 15 e00487, e00487. doi: 10.1016/j.idcr.2019.e00487
Stewart, Adam, Harris, Patrick, Henderson, Andrew and Paterson, David (2018). Treatment of infections with OXA-48 producing Enterobacteriaceae. Antimicrobial Agents and Chemotherapy, 62 (11) e01195-18, AAC.01195-18. doi: 10.1128/aac.01195-18
Stewart, Adam and Hajkowicz, Krispin (2018). Heterogeneity in skin manifestations of spotted fever group rickettsial infection in Australia. The Australasian Journal of Dermatology, 59 (4), 349-351. doi: 10.1111/ajd.12828
Stewart, A., Roberts, J. A., Wallis, S. C., Allworth, A. M., Legg, A. and McCarthy, K. L. (2018). Evidence of clinical response and stability of Ceftolozane/Tazobactam used to treat a carbapenem-resistant Pseudomonas Aeruginosa lung abscess on an outpatient antimicrobial program. International Journal of Antimicrobial Agents, 51 (6), 941-942. doi: 10.1016/j.ijantimicag.2018.02.008
Stewart, Adam, Armstrong, Mark, Graves, Stephen and Hajkowicz, Krispin (2017). Rickettsia Australis and Queensland tick typhus: a rickettsial spotted fever group infection in Australia. American Journal of Tropical Medicine and Hygiene, 97 (1), 24-29. doi: 10.4269/ajtmh.16-0915
Stewart, Adam, Armstrong, Mark, Graves, Stephen and Hajkowicz, Krispin (2017). Clinical manifestations and outcomes of Rickettsia australis infection: a 15-year retrospective study of hospitalized patients. Tropical Medicine and Infectious Disease, 2 (2) 19, 19. doi: 10.3390/tropicalmed2020019
Stewart, Adam, Armstrong, Mark, Graves, Stephen and Hajkowicz, Krispin (2017). Epidemiology and characteristics of Rickettsia australis (Queensland tick typhus) infection in hospitalized patients in North Brisbane, Australia. Tropical Medicine and Infectious Disease, 2 (2) 10, 10. doi: 10.3390/tropicalmed2020010
Stewart, Adam, Graves, Bianca, Hajkowicz, Krispin, Ta, Kim and Paterson, David L. (2015). The use of therapeutic drug monitoring to optimize treatment of carbapenem-resistant enterobacter osteomyelitis. Microbial Drug Resistance, 21 (6), 631-635. doi: 10.1089/mdr.2015.0006
Conference Paper
Stewart, Adam, Sarovich, Derek, Price, Erin, Burnard, Delaney, Harris, Patrick, Choong, Keat and Subedi, Shradha (2020). Molecular epidemiology and hospital spread of ceftriaxone non-susceptible enterobacterales in the Sunshine Coast region, Australia. RACP Congress 2020: Balancing medical science with humanity, Online, May 2020. Richmond, VIC Australia: Wiley-Blackwell. doi: 10.1111/imj.4_14846