Perinatal hypoxia-ischemia is detrimental to the developing brain and leads to white matter injury and often cerebral palsy (CP), but the related pathophysiological mechanisms remain unclear. We investigated the early and long-lasting mechanisms of pathophysiology that may be responsible for the various symptoms induced by mild intrauterine hypo perfusion (MIUH) and found persistent neurodevelopmental disorders of CP in this model. We are now investigating a prevention lead based on mesenchymal stem cells that appears very promising.

About CCR Seminars

The UQ Centre of Clinical Research Seminars (CCR) are held fortnightly on Wednesdays from 12pm - 1pm (except during school holidays) in the CCR Auditorium, Herston. The series features topics in the following fields of research, presented by invited international, interstate and local researchers.