Centre for Clinical Research

Dr Patrick Harris

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UQ Centre for Clinical Research
+61 7 3346 5476
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Dr Patrick Harris

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Research interest

Dr Patrick Harris is an Infectious Disease Physician, Medical Microbiologist and NHMRC Early Career Research Fellow at The University of Queensland Centre for Clinical Research (UQCCR).    

Dr. Harris obtained a BSc in Psychology and Anthropology from Durham University, prior to acquiring his medical degree from University College London Medical School.  Following postgraduate training in the UK he worked as a clinical lecturer at the College of Medicine in Malawi, and completed specialist training in infectious diseases and microbiology in Australia.  For his final year of training he was a Senior Visiting Fellow in Infectious Disease at the National University Hospital in Singapore. He has published more than 50 peer-reviewed articles, many as first author, including publications in JAMA, Lancet, Lancet Infectious Diseases and Clinical Infectious Diseases. He completed his PhD in 2018 under the supervision of Prof. David Paterson. He was the lead author on the MERINO trial, reported in JAMA in 2018. This was an international multicentre randomised clinical trial (RCT) to compare carbapenem-sparing treatment options for ESBL and AmpC-producing species.  This has been the first large RCT to specifically address this question, using a protocol developed and endorsed by the Australasian Society for Infectious Diseases Clinical Research Network (ASID-CRN). https://clinicaltrials.gov/ct2/show/NCT02176122. The trial enrolled over 390 patients from 30 centres in 9 countries. 

His research has a focus on antibiotic resistant bacteria and the use of randomised clinical trials to define optimal treatment for these problematic infections as well as the application of bacterial genomics to clinical practice. 

Research projects

Current active projects include:

  1. Pilot Randomised controlled trial of meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to AmpC-producing Enterobacter, Citrobacter, Serratia, Providencia and Morganella (MERINO-2 trial). https://clinicaltrials.gov/ct2/show/NCT02437045
  2. Queensland Genomic Health Alliance (QGHA) Clinical Demonstration Project: Whole genome sequencing to track, treat and prevent nosocomial infections. 
  3. Using whole genome sequencing to characterise carbapenem-resistant Enterobacteriaceae from QLD (the CREATE-Q Study), in collaboration with Pathology Queensland and A/Prof Scott Beatson (https://beatsonlab.com)
  4. Susceptibility of Burkholderia pseudomallei to a novel siderophore cephalosporin (cefiderocol) 
  5. Assessing the effects of antibiotics on the human gut microbiome of patients admitted to the ICU (with Dr. Sanmarie Schlebusch)
  6. Personalisation of antimicrobial therapy in critically ill patients: meeting a global challenge (Health Outcomes Program, with Prof. Jason Roberts)

Grant support

  1. NHMRC Early Career Fellowship Grant - Health Professional Research Fellowship 2019-2022: $232,315
  2. Pathology Queensland SERC 2018: CI-A, Rapid genomic detection of resistance in gram-negative pathogens causing bloodstream infection. $49,000.
  3. RWBH Foundation Grant 2018; CI-B (with CI-A David Paterson); Rapid characterisation of pathogens for personalised antimicrobial selection in critically ill patients. $49,634
  4. RWBH Foundation Grant 2018; AI with (CI-A Jason Roberts); Can software optimise antibiotic dosing in critically ill patients? $36,000
  5. Queensland Genomic Health Alliance 2017/8 Clinical Demonstration Project: Whole genome sequencing to track, treat and prevent nosocomial infections. $600,000 CIB with CIA Paterson.
  6. UQ Medicine Equipment and Infrastructure grant 2017; $84,950 – for Illumina MiniSeq instrument; with CI David Paterson
  7. RWBH Foundation Grant 2017: with Prof. David Paterson (CI-A) and Dr Andrew Henderson, $58,500. Pilot randomised controlled trials of Penicillin or Cefazolin versus Flucloxacillin for definitive treatment of invasive Penicillin Susceptible or Methicillin Susceptible Staphylococcus aureus.
  8. RCPA Foundation Postgraduate Research Fellowship 2017: $25,000
  9. Pathology Queensland Study, Education and Research Trust Fund 2016/7: $49,632. Assessing the effects of antibiotics in a randomised trial on the human gut microbiome
  10. Pathology Queensland Study, Education and Research Trust Fund 2016/7: A$45,000 awarded as co-investigator with Dr Claire Heney (funding for whole genome sequencing of carbapenem-resistant Enterobacteriaceae from QLD – the “CREATE-Q Study”)
  11. NUHS Clinician Researcher Grant FY2014: S$142,000 awarded for 2 years, collaborator with local PI Prof Paul Tambyah in Singapore (support for the MERINO Trial)
  12. Pathology Queensland Study, Education and Research Trust Fund 2015/6: A$47,136 awarded as co-investigator with Prof David Paterson (funding for whole genome sequencing of bacterial isolates from MERINO trials)
  13. RBWH Foundation Grant 2015: A$40,000, CIB with Prof David Paterson and Prof Jeff Lipman (to support the MERINO-2 trial)
  14. Australian Genome Research Facility (AGRF) 50:50 Sequencing Grant 2015/6: A$7,250 awarded as co-investigator with Prof David Paterson (to support whole genome sequencing)

Key publications

  1. Harris P, Tambyah PA, Lye DC, et al. Effect of piperacillin-tazobactam vs meropenem on 30-day mortality for patients with E coli or Klebsiella pneumoniae bloodstream infection and ceftriaxone resistance: A randomized clinical trial. JAMA. 2018;320(10):984-994.
  2.  Stewart A, Harris P, Henderson A, Paterson D. Treatment of Infections with OXA-48 producing Enterobacteriaceae. Antimicrob Agents Chemother. 2018.
  3. McNamara JF, Righi E, Wright H, Hartel GF, Harris PNA, Paterson DL. Long-term morbidity and mortality following bloodstream infection: A systematic literature review. J Infect. 2018 May 7. pii: S0163-4453(18)30120-8.
  4. Roberts MJ, Scott S, Harris PN, Naber K, Wagenlehner FME, Doi SAR. Comparison of fosfomycin against fluoroquinolones for transrectal prostate biopsy prophylaxis: an individual patient-data meta-analysis. World J Urol. 2017 Dec 29. 
  5. Forde BM, Zowawi HM, Harris PNA, et al. Discovery of mcr-1-Mediated Colistin Resistance in a Highly Virulent Escherichia coli Lineage. mSphere. 2018;3(5).
  6. Pang L, Harris PNA, Seiler RL, Ooi PL, Cutter J, Goh KT, et al. Melioidosis, Singapore, 2003–2014. Emerg Infect Dis. 2018 Jan
  7. Harris, P; Ben Zakour, N; Roberts, L; Wailan, A; Zowawi, H; Tambyah, P; Lye, D et al. Whole genome analysis of cephalosporin-resistant Escherichia coli from bloodstream infections in Australia, New Zealand and Singapore: high prevalence of CMY-2 producers and ST131 carrying blaCTX-M-15 and blaCTX-M-27. Jnl of Antimicrobial Chemother 2018. https://doi.org/10.1093/jac/dkx466 
  8. Djoko KY, Achard MES, Phan MD, Lo AW, Miraula M, Prombhul S, Hancock SJ, Peters KM, Sidjabat H, Harris PN, Mitić N, Walsh TR, Anderson GJ, Shafer WM, Paterson DL, Schenk G, McEwan AG, Schembri MA. Copper ions and coordination complexes as novel carbapenem adjuvants. Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.02280-17. doi: 10.1128/AAC.02280-17
  9. Harris PNA, M. Diletta Pezzani, Belén Gutiérrez-Gutiérrez, et al., Geographical variation in therapy for bloodstream infections due to multidrug-resistant : a post hoc analysis of the INCREMENT study, International Journal of Antimicrobial Agents, 2017, 2017 Nov;50(5):664-672. doi: 10.1016/j.ijantimicag.2017.08.005. Epub 2017 Aug 3.
  10. Webster J, Larsen E, Marsh N, Choudhury A, Harris P, Rickard CM. Chlorhexidine gluconate or polyhexamethylene biguanide disc dressing to reduce the incidence of central-line-associated bloodstream infection: a feasibility randomized controlled trial (the CLABSI trial). J Hosp Infect. 2017 Apr 16. pii: S0195-6701(17)30195-0. doi: 10.1016/j.jhin.2017.04.009. 
  11. Harris, PNA, Peri AM, Pelecanos AM, et al. (2017). Risk factors for relapse or persistence of bacteraemia caused by Enterobacter spp.: a case–control study. Antimicrobial Resistance & Infection Control 6(1): 14. 2017 Jan 21
  12. Roberts MJ, Bennett HY, Harris PN, et al. Prostate Biopsy Related Infection: a Systematic Review of Risk Factors, Prevention Strategies and Management Approaches. Urology 2016.104:11-21. doi: 10.1016/j.urology.2016.12.011. Epub 2016 Dec 19.
  13. Righi E, Peri AM, Harris PN, et al. Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis. J Antimicrob Chemother 2016.
  14. Rafiei N, Peri AM, Righi E, Harris P, Paterson DL. Central nervous system nocardiosis in Queensland: A report of 20 cases and review of the literature. Medicine (Baltimore) 2016; 95(46): e5255
  15. Harris PN, McNamara J, Lye D, Davis J, Bernard L, Cheng A, Doi Y, Fowler V, Kaye K, Leibovici L, Lipman J, Llewelyn M, Munoz-Price SL, Paul M, Peleg A, Rodriguez-Baño J, Rogers B, Seifert H, Thamlikitkul V, Thwaites G, Tong S, Turnidge JD, Utili R, Webb S & Paterson DL. Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition. Clinical Microbiology and Infection 2016. Nov 1. pii: S1198-743X(16)30512-2. 
  16. Huber CA, Sidjabat HE, Zowawi HM, Kvaskoff D, Reed S, McNamara JF, McCarthy KL, Harris P, Toh B, Wailan AM. Detection of carbapenemase activity in Enterobacteriaceae using LC-MS/MS in comparison with the neo-rapid CARB kit using direct visual assessment and colorimetry. J Microbiol Methods 2016; 131: 68-72.
  17. Ng TM, Khong WX, Harris PN, De PP, Chow A, Tambyah PA, Lye DC. Empiric Piperacillin-Tazobactam versus Carbapenems in the Treatment of Bacteraemia Due to Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae. PLoS One. 2016 Apr 22;11(4):e0153696.
  18. Paterson DL, Harris PN. Colistin resistance: a major breach in our last line of defence. Lancet Infect Dis. 2016 Feb;16(2):132-3.
  19. Harris PN, Oltvolgyi C, Islam A, Hussain-Yusuf H, et al. An outbreak of scrub typhus in military personnel despite protocols for antibiotic prophylaxis: doxycycline resistance excluded by a quantitative PCR-based susceptibility assay. Microbes Infect. 2016 Jun;18(6):406-11.
  20. Harris PN, Wei JY, Shen AW, Abdile AA, Paynter S, Huxley RR, Pandeya N, Doi Y, Huh K, O'Neal CS, Talbot TR, Paterson DL. Carbapenems versus alternative antibiotics for the treatment of bloodstream infections caused by Enterobacter, Citrobacter or Serratia species: a systematic review with meta-analysis. J Antimicrob Chemother. 2016 Feb;71(2):296-306.
  21. Zowawi HM*, Harris PN*, Roberts MJ, Tambyah PA, Schembri MA, Pezzani MD, Williamson DA, Paterson DL. The emerging threat of multidrug-resistant Gram-negative bacteria in urology. Nat Rev Urol. 2015 Oct;12(10):570-84. [*Joint 1st author].
  22. Khatri A, Naeger Murphy N, Wiest P, Osborn M, Garber K, Hecker M, Hurless K, Rudin SD, Jacobs MR, Kalayjian RC, Salata RA, van Duin D, Perez F, Bonomo RA, Paterson DL, Harris PN. Community-Acquired Pyelonephritis in Pregnancy Caused by KPC-Producing Klebsiella pneumoniae. Antimicrob Agents Chemother. 2015 Aug;59(8):4375-8.
  23. Harris PN, Le BD, Tambyah P, Hsu LY, Pada S, Archuleta S, Salmon S, Mukhopadhyay A, Dillon J, Ware R, Fisher DA. Antiseptic Body Washes for Reducing  the Transmission of Methicillin-Resistant Staphylococcus aureus: A Cluster Crossover Study. Open Forum Infect Dis. 2015 May 22;2(2).
  24. Harris PN, Yin M, Jureen R, Chew J, Ali J, Paynter S, Paterson DL, Tambyah PA. Comparable outcomes for β-lactam/β-lactamase inhibitor combinations and carbapenems in definitive treatment of bloodstream infections caused by cefotaxime-resistant Escherichia coli or Klebsiella pneumoniae. Antimicrob Resist Infect Control. 2015 May
  25. Paterson DL, Harris PN. Editorial commentary: the new Acinetobacter equation:  hypervirulence plus antibiotic resistance equals big trouble. Clin Infect Dis. 2015 Jul 15;61(2):155-6.
  26. Harris PN, Tambyah PA, Paterson DL. β-lactam and β-lactamase inhibitor combinations in the treatment of extended-spectrum β-lactamase producing Enterobacteriaceae: time for a reappraisal in the era of few antibiotic options?  Lancet Infect Dis. 2015 Apr;15(4):475-85.
  27. Harris PN. Clinical management of infections caused by Enterobacteriaceae that express extended-spectrum β-lactamase and AmpC enzymes. Semin Respir Crit Care Med. 2015 Feb;36(1):56-73.
  28. Harris PN, Peleg AY, Iredell J, Ingram PR, Miyakis S, Stewardson AJ, Rogers BA, McBryde ES, Roberts JA, Lipman J, Athan E, Paul SK, Baker P, Harris-Brown T,  Paterson DL. Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp (the MERINO trial): study protocol for a randomised controlled trial. Trials. 2015 Jan 27;16:24
  29. Fisher DA, Harris PN. Melioidosis: refining management of a tropical time bomb. Lancet. 2014 Mar 1;383(9919):762-4. Epub 2013 Nov 25.
  30. Harris PN, Wang AD, Yin M, Lee CK, Archuleta S. Atypical hand, foot, and mouth disease: eczema coxsackium can also occur in adults. Lancet Infect Dis. 2014 Nov;14(11):1043.
  31. Harris PN, Alder L, Paterson DL. Antimicrobial susceptibility reporting and treatment selection for AmpC-producing Enterobacteriaceae: what do microbiologists and infectious disease practitioners actually practice? Pathology 2015; 47(4): 386-8.
  32. Harris P, Paterson D, Rogers B. Facing the challenge of multidrug-resistant gram-negative bacilli in Australia. The Medical journal of Australia 2015; 202(5): 243-7.
  33. Harris P, Eales KM, Squires R, Govan B, Norton R. Acute Q fever in northern Queensland: variation in incidence related to rainfall and geographical location. Epidemiol Infect 2013; 141(5): 1034-8.
  34. Harris PN, Ferguson JK. Antibiotic therapy for inducible AmpC beta-lactamase-producing Gram-negative bacilli: what are the alternatives to carbapenems, quinolones and aminoglycosides? International journal of antimicrobial agents 2012; 40(4): 297-305.

View full list of publications 

Publications

Book Chapters (2)
Journal Articles (215)
Conference Papers (20)
Data Collections (2)

Book Chapters

Bennett, Harrison Y., Harris, Patrick N., Holmes, Michael, Grummet, Jeremy and Roberts, Matthew (2018). Prostate biopsy related infection – risk factors, prevention strategies and management approaches. Urogenital infections and inflammations. (pp. 1-30) edited by T.E. Bjerklund Johansen, F. M.E. Wagenlehner, Y.-H. Cho, T. Matsumoto, J. N. Krieger, D. Shoskes and K. Naber. Berlin, Germany: GMS Publishing House. doi: 10.5680/lhuii000040
Peleg, A. Y. and Harris, P. (2017). Meropenem / Meropenem-vaborbactam. Kucers' the Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic and Antiviral Drugs. (pp. 697-722) edited by Lindsay Grayson. Boca Raton, FL United States: Taylor & Francis. doi: 10.1201/9781315152110

Journal Articles

Edwards, Felicity, Edwards, Kristin H., Tabah, Alexis, Harris, Patrick N.A. and Laupland, Kevin B. (2025). Differentiation of Providencia species bloodstream infections: A population-based analysis. Diagnostic Microbiology and Infectious Disease, 111 (1) 116602. doi: 10.1016/j.diagmicrobio.2024.116602
Peri, Anna Maria, O’Callaghan, Kevin, Rafiei, Nastaran, Bergh, Haakon, Tabah, Alexis, Chatfield, Mark D, Harris, Patrick NA and Paterson, David L (2024). Integrating omics techniques and culture-independent systems may improve the detection of persistent candidemia: data from an observational study. Annals of Clinical Microbiology and Antimicrobials, 23 (1) 75. doi: 10.1186/s12941-024-00736-w
Hardy, Melissa J., Harris, Patrick N. A., Chatfield, Mark D., Mo, Yin and Paterson, David L. (2024). Exploring desirability of outcome ranking and generalised pairwise comparisons as endpoints in serious infections: post hoc application with the MERINO trial. CMI Communications, 1 (2) 105040, 1-7. doi: 10.1016/j.cmicom.2024.105040
Gibbs, Anna A.M., Laupland, Kevin B., Edwards, Felicity, Ling, Weiping, Channon-Wells, Samuel, Harley, David, Falster, Kathleen, Paterson, David L., Harris, Patrick N.A. and Irwin, Adam D. (2024). Trends in Enterobacterales Bloodstream Infections in Children. Pediatrics, 154 (4) e2023063532. doi: 10.1542/peds.2023-063532
Wen, Sophie C. H., Harris, Patrick N. A., Forde, Brian, Permana, Budi, Chatfield, Mark D., Lau, Colleen L., Spurling, Geoffrey, Bauer, Michelle J., Balch, Ross, Chambers, Henry, Schlapbach, Luregn J., Clark, Julia E., Dougherty, Sonia, Blyth, Christopher C., Britton, Philip N., Clifford, Vanessa, Haeusler, Gabrielle M., McMullan, Brendan, Wadia, Ushma, Paterson, David L., Irwin, Adam D., on behalf of the PAEDS network, Carr, Jeremy, Vasilunas, Nan, Francis, Joshua R., Macartney, Kristine, Crawford, Nigel W., Wood, Nicholas, Buttery, Jim ... Glover, Catherine (2024). Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomes. Clinical Infectious Diseases, 79 (3), 734-743. doi: 10.1093/cid/ciae341
Liborio, Mariana P., Harris, Patrick N. A., Ravi, Chitra and Irwin, Adam D. (2024). Getting up to speed: Rapid pathogen and antimicrobial resistance diagnostics in sepsis. Microorganisms, 12 (9) 1824, 1-29. doi: 10.3390/microorganisms12091824
Subedi, Shradha, Isler, Burcu, Ezure, Yukiko, Furuya-Kanamori, Luis, Eriksson, Lars, Paterson, David L and Harris, Patrick N. A. (2024). Performance characteristics of genus or species-specific Polymerase Chain Reaction (PCR) for the microbial diagnosis of joint infections: a systematic review and meta-analysis. Diagnostic Microbiology and Infectious Disease, 110 (1) 116422, 1-8. doi: 10.1016/j.diagmicrobio.2024.116422
Peri, Anna Maria, Chatfield, Mark D., Ling, Weiping, Furuya-Kanamori, Luis, Harris, Patrick N. A. and Paterson, David L. (2024). Rapid diagnostic tests and antimicrobial stewardship programs for the management of bloodstream infection: What is their relative contribution to improving clinical outcomes? A systematic review and network meta-analysis. Clinical Infectious Diseases, 79 (2), 502-515. doi: 10.1093/cid/ciae234
Gassiep, Ian, Chatfield, Mark D., Permana, Budi, Burnard, Delaney, Bauer, Michelle J., Cuddihy, Thom, Forde, Brian M., Mayer-Coverdale, Johanna, Norton, Robert E. and Harris, Patrick N. A. (2024). The genomic epidemiology of clinical Burkholderia pseudomallei isolates in North Queensland, Australia. Pathogens, 13 (7) 584. doi: 10.3390/pathogens13070584
Langham, Freya, Tsai, Danny, Forde, Brian M., Camilleri, Shayne, Harris, Patrick N.A., Roberts, Jason A. and Chiong, Fabian (2024). Demographic, clinical and molecular epidemiology of extended-spectrum beta-lactamase-producing Escherichia coli bloodstream infections in Central Australia. Pathology, 56 (7), 1012-1020. doi: 10.1016/j.pathol.2024.04.013
Laupland, Kevin B., Edwards, Felicity and Harris, Patrick N.A. (2024). Proteus species bloodstream infections: Comparative epidemiology of three species. Diagnostic Microbiology and Infectious Disease, 109 (2) 116286, 116286. doi: 10.1016/j.diagmicrobio.2024.116286
Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Hancock, Steven J., Peters, Kate M., Alvarez-Fraga, Laura, Forde, Brian M., Andersen, Stacey B., Miliya, Thyl, Harris, Patrick N. A., Beatson, Scott A., Schlebusch, Sanmarie, Bergh, Haakon, Turner, Paul, Brauner, Annelie, Westerlund-Wikström, Benita, Irwin, Adam D. and Schembri, Mark A (2024). High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection. eLife, 12 ARTN RP91853. doi: 10.7554/elife.91853.3
Chai, Ming G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., Mcwhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (5), 810-810. doi: 10.1007/s00134-024-07393-9
Horcajada, Juan P., Edwards, Felicity, Fonio, Silvia, Montero, Milagro, Harris, Patrick, Paterson, David L. and Laupland, Kevin B. (2024). Pseudomonas stutzeri bloodstream infection is a prevailing community-onset disease with important mortality rates: results from a retrospective observational study in Australia. Infectious Diseases, ahead-of-print (ahead-of-print), 1-10. doi: 10.1080/23744235.2024.2333979
Nong, Yi, Steinig, Eike, Pollock, Georgina L., Taiaroa, George, Carter, Glen P., Monk, Ian R., Pang, Stanley, Daley, Denise A., Coombs, Geoffrey W., Forde, Brian M., Harris, Patrick N. A., Sherry, Norelle L., Howden, Benjamin P., Pasricha, Shivani, Baines, Sarah L. and Williamson, Deborah A. (2024). Emergence and clonal expansion of a qacA-harbouring sequence type 45 lineage of methicillin-resistant Staphylococcus aureus. Communications Biology, 7 (1) 349, 349. doi: 10.1038/s42003-024-06012-z
Chai, Gene G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., McWhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (4), 1-9. doi: 10.1007/s00134-024-07353-3
Laupland, Kevin B., Edwards, Felicity, Dettrick, Zoe and Harris, Patrick N.A. (2024). Time to positivity is a risk factor for death among patients with bloodstream infections: A population-based cohort. Clinical Microbiology and Infection, 30 (7), 899-904. doi: 10.1016/j.cmi.2024.03.032
Peri, Anna Maria, O’Callaghan, Kevin, Rafiei, Nastaran, Graves, Bianca, Sinclair, Holly, Brischetto, Anna, Lim, Karen, Parkes-Smith, Jill, Eustace, Matthew, Davidson, Natalie, Tabah, Alexis, Stewart, Adam, Chatfield, Mark D, Harris, Patrick NA and Paterson, David L (2024). Persistence of detectable pathogens by culture independent systems (T2 Magnetic Resonance) in patients with bloodstream infection: prognostic role and possible clinical implications. Clinical Infectious Diseases, 78 (2), 283-291. doi: 10.1093/cid/ciad663
Permana, Budi, Harris, Patrick N. A., Roberts, Leah W., Cuddihy, Thom, Paterson, David L., Beatson, Scott A. and Forde, Brian M. (2024). HAIviz: an interactive dashboard for visualising and integrating healthcare-associated genomic epidemiological data. Microbial Genomics, 10 (2) 001200. doi: 10.1099/mgen.0.001200
Hardy, Melissa, Harris, Patrick N. A., Paterson, David L., Chatfield, Mark D., Mo, Yin, for the MERINO trial investigators, Tambyah, Paul A., Lye, David C., Lee, Tau H., Yilmaz, Mesut, Alenazi, Thamer H., Arabi, Yaseen, Falcone, Marco, Bassetti, Matteo, Righi, Elda, Rogers, Benjamin A., Kanj, Souha, Bhally, Hasan, Iredell, Jon, Mendelson, Marc, Boyles, Tom H., Looke, David, Miyakis, Spiros, Walls, Genevieve, Al Khamis, Mohammed, Zikri, Ahmed, Crowe, Amy, Ingram, Paul, Daneman, Nick ... Peleg, Anton Y. (2024). Win ratio analyses of piperacillin-tazobactam versus meropenem for ceftriaxone non-susceptible Escherichia coli or Klebsiella pneumoniae bloodstream infections: Post-hoc insights from the MERINO trial. Clinical Infectious Diseases, 78 (6), 1482-1489. doi: 10.1093/cid/ciae050
Li, Yixuan, Roberts, Jason A., Walker, Mikaela M., Aslan, Abdullah Tarik, Harris, Patrick N. A. and Sime, Fekade (2024). The global epidemiology of ventilator-associated pneumonia caused by multi-drug resistant Pseudomonas aeruginosa: a systematic review and meta-analysis. International Journal of Infectious Diseases, 139, 78-85. doi: 10.1016/j.ijid.2023.11.023
Stewart, Adam G., Harris, Patrick N.A., Graham, Rikki M.A., Jennison, Amy V., Schlebusch, Sanmarie, Harris-Brown, Tiffany, Paterson, David L. and Forde, Brian M. (2024). Differences in antimicrobial resistance gene abundance and microbial diversity of the gut microbiome in patients on antibiotics enrolled in a clinical trial. Pathology, 56, S36-S37. doi: 10.1016/j.pathol.2023.12.137
Aslan, Abdullah Tarik, Ezure, Yukiko, Harris, Patrick N. A. and Paterson, David L. (2024). Scoping review of risk-scoring tools for early prediction of bloodstream infections caused by carbapenem-resistant Enterobacterales: do we really have a reliable risk-scoring tool?. JAC-Antimicrobial Resistance, 6 (1) dlae032, 1-9. doi: 10.1093/jacamr/dlae032
Harris, Patrick N. A., Bauer, Michelle J., Lüftinger, Lukas, Beisken, Stephan, Forde, Brian M., Balch, Ross, Cotta, Menino, Schlapbach, Luregn, Raman, Sainath, Shekar, Kiran, Kruger, Peter, Lipman, Jeff, Bialasiewicz, Seweryn, Coin, Lachlan, Roberts, Jason A., Paterson, David L. and Irwin, Adam D. (2024). Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis. Microbiology spectrum, 12 (2) e0306523, e0306523. doi: 10.1128/spectrum.03065-23
Peri, Anna Maria, Harris, Patrick N. A. and Paterson, David L. (2024). Host response signature trends in bacteraemia–authors’ response. Infectious Diseases, 56 (5), 1-3. doi: 10.1080/23744235.2024.2326591
Davidson, Natalie, Edwards, Felicity, Harris, Patrick N.A. and Laupland, Kevin B. (2024). Vibrio species bloodstream infections in Queensland, Australia. Internal Medicine Journal, 54 (1), 157-163. doi: 10.1111/imj.16187
Ling, Weiping, Paterson, David L., Harris, Patrick N. A., Furuya-Kanamori, Luis, Edwards, Felicity and Laupland, Kevin B. (2024). Mortality, hospital length of stay and recurrent bloodstream infections associated with extended-spectrum beta-lactamase producing Escherichia coli (ESBL-Ec) in a low prevalence region: a 20-year population-based large cohort study. International Journal of Infectious Diseases, 138, 84-90. doi: 10.1016/j.ijid.2023.11.007
Peri, Anna Maria, Rafiei, Nastaran, O’Callaghan, Kevin, Brischetto, Anna, Graves, Bianca, Sinclair, Holly, Eustace, Matthew, Lim, Karen, Parkes-Smith, Jill, Stewart, Adam, Davidson, Natalie, Tabah, Alexis, Bergh, Haakon, Chatfield, Mark D., Harris, Patrick N. A. and Paterson, David L. (2023). Host response signature trends in persistent bacteraemia and metastatic infection due to Staphylococcus aureus and Gram-negative bacilli: a prospective multicentre observational study. Infectious Diseases, 56 (4), 268-276. doi: 10.1080/23744235.2023.2294122
Lowry, Kym, Bauer, Michelle J., Buckley, Cameron, Wang, Claire, Bordin, Amanda, Badman, Steven, Harris, Patrick N.A., Mackay, Ian and Whiley, David (2023). Evaluation of Illumina® COVIDSeq™ as a Tool for Omicron SARS-CoV-2 Characterisation. Journal of Virological Methods, 322 114827, 1-5. doi: 10.1016/j.jviromet.2023.114827
Tamma, Pranita D., Harris, Patrick N. A., Mathers, Amy J., Wenzler, Eric and Humphries, Romney M. (2023). Breaking Down the Breakpoints: Rationale for the 2022 Clinical and Laboratory Standards Institute Revised Piperacillin-Tazobactam Breakpoints Against Enterobacterales. Clinical Infectious Diseases, 77 (11), 1585-1590. doi: 10.1093/cid/ciac688
Aslan, Abdullah Tarik, Permana, Budi, Harris, Patrick N. A., Naidoo, Kuban D., Pienaar, Michael A. and Irwin, Adam D. (2023). The opportunities and challenges for artificial intelligence to improve sepsis outcomes in the paediatric intensive care unit. Current Infectious Disease Reports, 25 (11), 243-253. doi: 10.1007/s11908-023-00818-4
Blaskovich, Mark A. T. and Harris, Patrick N. A. (2023). Bugs in floods. Microbiology Australia, 44 (4), 176-180. doi: 10.1071/ma23051
Gassiep, Ian, Burnard, Delaney, Permana, Budi, Bauer, Michelle J., Cuddihy, Thom, Forde, Brian M., Chatfield, Mark D., Ling, Weiping, Norton, Robert and Harris, Patrick N. A. (2023). Melioidosis Queensland: an analysis of clinical outcomes and genomic factors. PLoS Neglected Tropical Diseases, 17 (10) e0011697, 1-13. doi: 10.1371/journal.pntd.0011697
Peri, Anna Maria, Edwards, Felicity, Henden, Andrea, Harris, Patrick N. A., Chatfield, Mark D., Paterson, David L. and Laupland, Kevin B. (2023). Bloodstream infections in neutropenic and non-neutropenic patients with haematological malignancies: epidemiological trends and clinical outcomes in Queensland, Australia over the last 20 years. Clinical and Experimental Medicine, 23 (8), 4563-4573. doi: 10.1007/s10238-023-01206-x
Aslan, Abdullah Tarık, Ezure, Yukiko, Horcajada, Juan Pablo, Harris, Patrick N. A. and Paterson, David L. (2023). In vitro, in vivo and clinical studies comparing the efficacy of ceftazidime-avibactam monotherapy with ceftazidime-avibactam-containing combination regimens against carbapenem-resistant Enterobacterales and multidrug-resistant Pseudomonas aeruginosa isolates or infections: a scoping review. Frontiers in Medicine, 10 1249030, 1-16. doi: 10.3389/fmed.2023.1249030
Stewart, Adam G., Heney, Claire, Paterson, David L., Harris, Patrick N.A., Edwards, Felicity and Laupland, Kevin B. (2023). Scedosporium species and Lomentospora prolificans fungaemia is uniformly fatal in patients with haematological malignancy. Internal Medicine Journal, 53 (8), 1489-1491. doi: 10.1111/imj.16198
Isler, Burcu, Vatansever, Cansel, Özer, Berna, Çınar, Güle, Aslan, Abdullah Tarık, Falconer, Caitlin, Bauer, Michelle J., Forde, Brian, Şimşek, Funda, Tülek, Necla, Demirkaya, Hamiyet, Menekşe, Şirin, Akalin, Halis, Balkan, İlker İnanç, Aydın, Mehtap, Tigen, Elif Tükenmez, Demir, Safiye Koçulu, Kapmaz, Mahir, Keske, Şiran, Doğan, Özlem, Arabacı, Çiğdem, Yağcı, Serap, Hazırolan, Gülşen, Bakır, Veli Oğuzalp, Gönen, Mehmet, Saltoğlu, Neşe, Azap, Alpay, Azap, Özlem, Akova, Murat ... Harris, Patrick N. A. (2023). Higher rates of cefiderocol resistance among NDM producing Klebsiella bloodstream isolates applying EUCAST over CLSI breakpoints. Infectious Diseases, 55 (9), 607-613. doi: 10.1080/23744235.2023.2226709
Rogers, Benjamin A., Fowler, Robert, Harris, Patrick N. A., Davis, Joshua S., Pinto, Ruxandra L., Bhatia Dwivedi, Dhiraj, Rishu, Asgar, Shehabi, Yahya and Daneman, Nick (2023). Non-inferiority trial of a shorter (7 days) compared with a longer (14 days) duration of antimicrobial therapy for the treatment of bacteraemic urinary sepsis, measured by microbiological success after the completion of therapy: a substudy protocol for the Bacteraemia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) multicentre randomised controlled trial. BMJ Open, 13 (6) e069708. doi: 10.1136/bmjopen-2022-069708
Peters, Nathan, Williamson, Frances, Bauer, Michelle J., Llewellyn, Stacey, Snelling, Peter J., Marsh, Nicole, Harris, Patrick N. A., Stewart, Adam G. and Rickard, Claire M. (2023). Comparison of low‐level to high‐level disinfection in eliminating microorganisms from ultrasound transducers used on skin : a noninferiority randomized controlled trial. Journal of Ultrasound in Medicine, 42 (11), 2525-2534. doi: 10.1002/jum.16286
Permana, Budi, Harris, Patrick N. A., Runnegar, Naomi, Lindsay, Margaret, Henderson, Belinda C., Playford, E. G., Paterson, David L., Beatson, Scott A. and Forde, Brian M. (2023). Using genomics to investigate an outbreak of vancomycin-resistant Enterococcus faecium ST78 at a large tertiary hospital in Queensland. Microbiology Spectrum, 11 (3) e0420422, 1-10. doi: 10.1128/spectrum.04204-22
Tamma, Pranita D., Harris, Patrick N. A., Mathers, Amy J., Wenzler, Eric and Humphries, Romney M. (2023). Deconstructing the 2023 Clinical and Laboratory Standards revised piperacillin-tazobactam breakpoints against Pseudomonas aeruginosa. Clinical Infectious Diseases, 76 (10), 1868-1870. doi: 10.1093/cid/ciad012
Gassiep, Ian, Grey, Victoria, Thean, Li Jun, Farquhar, Drew, Clark, Julia E., Ariotti, Lawrence, Graham, Rikki, Jennison, Amy V., Bergh, Haakon, Anuradha, Satyamurthy, Dyer, Wendy, James, Christian, Huang, Andrea, Putt, Elise, Pakeerathan, Veenaa, Griffin, Paul M. and Harris, Patrick N. A. (2023). Expanding the geographic boundaries of Melioidosis in Queensland, Australia. The American Journal of Tropical Medicine and Hygiene, 108 (6), 1215-1219. doi: 10.4269/ajtmh.23-0002
Laupland, Kevin B., Edwards, Felicity, Furuya-Kanamori, Luis, Paterson, David L. and Harris, Patrick N. A. (2023). Bloodstream infection and colorectal cancer risk in Queensland Australia, 2000-2019. The American Journal of Medicine, 136 (9), 896-901. doi: 10.1016/j.amjmed.2023.05.003
Stewart, Adam G., Bauer, Michelle J., Butkiewicz, Dominika, Hinton, Alexandra, Henderson, Andrew, Harris, Patrick N.A. and Paterson, David L. (2023). In vitro activity of oral third-generation cephalosporins plus clavulanate against ESBL-producing Enterobacterales isolates from the MERINO trial. International Journal of Antimicrobial Agents, 62 (2) 106858, 1-4. doi: 10.1016/j.ijantimicag.2023.106858
Ertl, Nicole G., Irwin, Adam D., Macdonald, Joanne, Bauer, Michelle J., Wang, Claire Y. T., Harris, Patrick N. A., Heney, Claire, Zowawi, Hosam M. and Whiley, David M. (2023). Rapid molecular detection of CMY-2, and CTX-M group 1 and 9 variants via recombinase polymerase amplification. JAC - Antimicrobial Resistance, 5 (2) dlad023, dlad023. doi: 10.1093/jacamr/dlad023
Dong, Xiaomin, Deng, Yi-Mo, Aziz, Ammar, Whitney, Paul, Clark, Julia, Harris, Patrick, Bautista, Catherine, Costa, Anna-Maria, Waller, Gregory, Daley, Andrew J, Wieringa, Megan, Korman, Tony and Barr, Ian G. (2023). A simplified, amplicon-based method for whole genome sequencing of human respiratory syncytial viruses. Journal of Clinical Virology, 161 105423, 1-6. doi: 10.1016/j.jcv.2023.105423
Laupland, Kevin B., Edwards, Felicity, Harris, Patrick N. A. and Paterson, David L. (2023). Significant clinical differences but not outcomes between Klebsiella aerogenes and Enterobacter cloacae bloodstream infections: a comparative cohort study. Infection, 51 (5), 1445-1451. doi: 10.1007/s15010-023-02010-1
Ling, Weiping, Paterson, David L., Harris, Patrick N. A., Furuya-Kanamori, Luis, Edwards, Felicity and Laupland, Kevin B. (2023). Population-based incidence and characteristics of adult Escherichia coli bloodstream infection in Queensland, Australia from 2000 to 2019. Open Forum Infectious Diseases, 10 (3) ofad071, ofad071. doi: 10.1093/ofid/ofad071
Kwok, M., McGeorge, S., Mayer-Coverdale, J., Graves, B., Paterson, D. L., Harris, P. N. A., Esler, R., Dowling, C., Britton, S. and Roberts, M. J. (2023). Infection and inflammation of the genitourinary tract. Journal of Urology, 209 (3), 617-617. doi: 10.1097/JU.0000000000003090
Stewart, Adam G., Roberts, Jason A., Forde, Brian M., Bergh, Haakon, Kidd, Timothy J., Wright, Hugh and Harris, Patrick N. A. (2023). Treatment Failure Due to Adaptive Resistance Mechanisms in a Severe and Complicated Bloodstream Infection Due to . Microbial Drug Resistance, 29 (4), 145-149. doi: 10.1089/mdr.2022.0179
Parkes-Smith, Jill, Bergh, Haakon and Harris, Patrick N.A. (2023). Assessing the performance of the Cepheid Xpert in identifying and differentiating methicillin-susceptible Staphylococcus aureus and methicillin-resistant Staphylococcus aureus from blood culture bottles. Pathology, 55 (1), 113-116. doi: 10.1016/j.pathol.2022.07.006
Schults, Jessica, Edwards, Felicity, Charles, Karina, Irwin, Adam D., Rickard, Claire M., Harris, Patrick N. A., Paterson, David L. and Laupland, Kevin (2023). Evolving insights into the epidemiology of Moraxella species bloodstream infection from two decades of surveillance in Queensland, Australia. European Journal of Clinical Microbiology and Infectious Diseases, 42 (2), 209-216. doi: 10.1007/s10096-022-04540-2
Corley, Amanda, Ullman, Amanda J., Marsh, Nicole, Genzel, Jodie, Larsen, Emily N., Young, Emily, Booker, Catriona, Harris, Patrick N. A. and Rickard, Claire M. (2023). A pilot randomized controlled trial of securement bundles to reduce peripheral intravenous catheter failure. Heart and Lung, 57, 45-53. doi: 10.1016/j.hrtlng.2022.07.015
Sinclair, Holly A., Edwards, Felicity, Harris, Patrick N. A., Heney, Claire and Laupland, Kevin B. (2023). Epidemiology of Aeromonas species bloodstream infection in Queensland, Australia: association with regional and climate zones. Microorganisms, 11 (1) 36, 36. doi: 10.3390/microorganisms11010036
Isler, Burcu, Falconer, Caitlin, Vatansever, Cansel, Özer, Berna, Çınar, Güle, Aslan, Abdullah Tarık, Forde, Brian, Harris, Patrick, Şimşek, Funda, Tülek, Necla, Demirkaya, Hamiyet, Menekşe, Şirin, Akalin, Halis, Balkan, İlker İnanç, Aydın, Mehtap, Tigen, Elif Tükenmez, Demir, Safiye Koçulu, Kapmaz, Mahir, Keske, Şiran, Doğan, Özlem, Arabacı, Çiğdem, Yağcı, Serap, Hazırolan, Gülşen, Bakır, Veli Oğuzalp, Gönen, Mehmet, Saltoğlu, Neşe, Azap, Alpay, Azap, Özlem, Akova, Murat ... Paterson, David L. (2022). High prevalence of ArmA-16S rRNA methyltransferase among aminoglycoside-resistant Klebsiella pneumoniae bloodstream isolates. Journal of Medical Microbiology, 71 (12) 001629, 1-8. doi: 10.1099/jmm.0.001629
Walker, Mikaela M., Roberts, Jason A., Rogers, Benjamin A., Harris, Patrick N. A. and Sime, Fekade B. (2022). Current and emerging treatment options for multidrug resistant Escherichia coli urosepsis: a review. Antibiotics, 11 (12) 1821, 1-20. doi: 10.3390/antibiotics11121821
Griskaitis, Matas, Furuya-Kanamori, Luis, Allel, Kasim, Stabler, Richard, Harris, Patrick, Paterson, David L. and Yakob, Laith (2022). β-lactam-resistant Streptococcus pneumoniae dynamics following treatment: a dose-response meta-analysis. Clinical Infectious Diseases, 75 (11), 1962-1970. doi: 10.1093/cid/ciac293
Parkes-Smith, Jill, Bauer, Michelle J., Bergh, Haakon, Eidan, Anthony, Forde, Brian M., Hilton, John, Kidd, Timothy J., Schmidt, Campbell, Stewart, Adam G. and Harris, Patrick N. A. (2022). Case report: a fatal case of Aspergillus felis infection in an immunocompetent host. Access Microbiology, 4 (11) acmi000453, 1-4. doi: 10.1099/acmi.0.000453
Laupland, Kevin B., Harris, Patrick N. A., Stewart, Adam G., Edwards, Felicity and Paterson, David L. (2022). Culture-based determinants and outcome of Staphylococcus aureus bloodstream infections. Diagnostic Microbiology and Infectious Disease, 104 (3) 115772, 1-5. doi: 10.1016/j.diagmicrobio.2022.115772
Bauer, Michelle J., Peri, Anna Maria, Lüftinger, Lukas, Beisken, Stephan, Bergh, Haakon, Forde, Brian M., Buckley, Cameron, Cuddihy, Thom, Tan, Patrice, Paterson, David L., Whiley, David M. and Harris, Patrick N. A. (2022). Optimized method for bacterial nucleic acid extraction from positive blood culture broth for whole-genome sequencing, resistance phenotype prediction, and downstream molecular applications. Journal of Clinical Microbiology, 60 (11) e01012-22, 1-11. doi: 10.1128/jcm.01012-22
Ling, Weiping, Cadavid-Restrepo, Angela, Furuya-Kanamori, Luis, Harris, Patrick N.A. and Paterson, David L. (2022). Incidence and predictors of Escherichia coli producing extended-spectrum beta-lactamase (ESBL-Ec) in Queensland, Australia from 2010 to 2019: a population-based spatial analysis. Epidemiology and Infection, 150 e178, 1-27. doi: 10.1017/s0950268822001637
Peri, Anna Maria, Ling, Weiping, Furuya-Kanamori, Luis, Harris, Patrick N. A. and Paterson, David L. (2022). Performance of BioFire Blood Culture Identification 2 Panel (BCID2) for the detection of bloodstream pathogens and their associated resistance markers: a systematic review and meta-analysis of diagnostic test accuracy studies. BMC Infectious Diseases, 22 (1) 794, 1-14. doi: 10.1186/s12879-022-07772-x
Edwards, Felicity, Glen, Kate, Harris, Patrick N. A., Paterson, David L. and Laupland, Kevin B. (2022). Determinants and outcomes of bloodstream infections related to obesity. European Journal of Clinical Microbiology and Infectious Diseases, 41 (11), 1347-1353. doi: 10.1007/s10096-022-04501-9
Ranasinghe, Ama, Henderson, Andrew, Cottrell, Kyra, Tan, Cindy S. E., Burnard, Delaney, Kato, Hideo, Paterson, David L. and Harris, Patrick N. A. (2022). Determining the in vitro susceptibility of tebipenem, an oral carbapenem, against third-generation cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae isolated from bloodstream infections. JAC-Antimicrobial Resistance, 4 (5) dlac105, 1-6. doi: 10.1093/jacamr/dlac105
Forde, Brian M., Bergh, Haakon, Cuddihy, Thom, Hajkowicz, Krispin, Hurst, Trish, Playford, E Geoffrey, Henderson, Belinda C., Runnegar, Naomi, Clark, Julia, Jennison, Amy V., Moss, Susan, Hume, Anna, Leroux, Hugo, Beatson, Scott A., Paterson, David L. and Harris, Patrick N. A. (2022). Clinical implementation of routine whole-genome sequencing for hospital infection control of multi-drug resistant pathogens. Clinical Infectious Diseases, 76 (3), e1277-e1284. doi: 10.1093/cid/ciac726
Isler, Burcu, Vatansever, Cansel, Özer, Berna, Çınar, Güle, Aslan, Abdullah Tarık, Stewart, Adam, Simos, Peter, Falconer, Caitlin, Bauer, Michelle J., Forde, Brian, Harris, Patrick, Şimşek, Funda, Tülek, Necla, Demirkaya, Hamiyet, Menekşe, Şirin, Akalin, Halis, Balkan, İlker İnanç, Aydın, Mehtap, Tigen, Elif Tükenmez, Demir, Safiye Koçulu, Kapmaz, Mahir, Keske, Şiran, Doğan, Özlem, Arabacı, Çiğdem, Yağcı, Serap, Hazırolan, Gülşen, Bakır, Veli Oğuzalp, Gönen, Mehmet, Saltoğlu, Neşe ... Can, Füsun (2022). Comparison of ceftazidime-avibactam susceptibility testing methods against OXA-48-like carrying Klebsiella blood stream isolates. Diagnostic Microbiology and Infectious Disease, 104 (1) 115745, 1-4. doi: 10.1016/j.diagmicrobio.2022.115745
Browne, Daniel J., Liang, Fang, Gartlan, Kate H., Harris, Patrick N. A., Hill, Geoffrey R., Corrie, Simon R. and Markey, Kate A. (2022). Multiplex microsphere PCR (mmPCR) allows simultaneous gram typing, detection of fungal DNA, and antibiotic resistance genes. Laboratory Medicine, 53 (5), 459-464. doi: 10.1093/labmed/lmac023
Sumi, Chandra Datta, Heffernan, Aaron J., Naicker, Saiyuri, Cottrell, Kyra, Wallis, Steven C., Lipman, Jeffrey, Harris, Patrick N. A., Sime, Fekade B. and Roberts, Jason A. (2022). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Escherichia coli clinical isolates. Journal of Antimicrobial Chemotherapy, 77 (11), 3026-3034. doi: 10.1093/jac/dkac273
Lowry, Kym, Wang, Claire, Bordin, Amanda, Buckley, Cameron, Badman, Steven, Harris, Patrick, Mackay, Ian and Whiley, David (2022). SARS-CoV-2 RT-PCR to screen for B.1.617.2 (Delta) Variant of Concern. Diagnostics, 12 (9) 2056, 1-7. doi: 10.3390/diagnostics12092056
Islam, Kamrul, Sime, Fekade B., Wallis, Steven C., Bauer, Michelle J., Naicker, Saiyuri, Won, Hayoung, Zowawi, Hosam M., Choudhury, Md Abu, Shirin, Tahmina, Habib, Zakir H., Harris, Patrick N. A., Flora, Meerjady S. and Roberts, Jason A. (2022). Pharmacodynamics of Piperacillin-Tazobactam/Amikacin Combination versus Meropenem against Extended-Spectrum β-Lactamase-Producing Escherichia coli in a Hollow Fiber Infection Model. Antimicrobial Agents and Chemotherapy, 66 (9), e0016222. doi: 10.1128/aac.00162-22
Islam, Kamrul, Sime, Fekade B., Bauer, Michelle J., Forde, Brian M., Wallis, Steven C., Harris, Patrick, Naicker, Saiyuri, Shirin, Tahmina, Habib, Zakir H., Flora, Meerjady S. and Roberts, Jason A. (2022). Pharmacodynamic evaluation of piperacillin/tazobactam against extended-spectrum β-lactamase-producing versus non-producing Escherichia coli in a hollow-fibre infection model. International Journal of Antimicrobial Agents, 60 (2) 106623, 1-7. doi: 10.1016/j.ijantimicag.2022.106623
Isler, Burcu, Paterson, David L., Harris, Patrick N. A., Ling, Weiping, Edwards, Felicity, Rickard, Claire M., Kidd, Timothy J., Gassiep, Ian and Laupland, Kevin B. (2022). Achromobacter species: an emerging cause of community-onset bloodstream infections. Microorganisms, 10 (7) 1449, 1-9. doi: 10.3390/microorganisms10071449
Peri, Anna Maria, Bauer, Michelle J., Bergh, Haakon, Butkiewicz, Dominika, Paterson, David L. and Harris, Patrick N. A. (2022). Performance of the BioFire Blood Culture Identification 2 Panel for the diagnosis of bloodstream infections. Heliyon, 8 (7) e09983, 1-6. doi: 10.1016/j.heliyon.2022.e09983
Ling, Weiping, Peri, Anna Maria, Furuya-Kanamori, Luis, Harris, Patrick N.A. and Paterson, David L. (2022). Carriage duration and household transmission of Enterobacterales producing extended-spectrum beta-lactamase in the community: a systematic review and meta-analysis. Microbial Drug Resistance, 28 (7), 1-11. doi: 10.1089/mdr.2022.0035
Islam, Kamrul, Sime, Fekade B., Wallis, Steven C., Bauer, Michelle J., Forde, Brian M., Harris, Patrick, Shirin, Tahmina, Habib, Zakir H., Flora, Meerjady S. and Roberts, Jason A. (2022). Pharmacodynamic evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum β-lactamase-producing and non-producing Escherichia coli clinical isolates in a hollow-fibre infection model. Journal of Antimicrobial Chemotherapy, 77 (9), 2448-2455. doi: 10.1093/jac/dkac186
Burnard, Delaney, Bauer, Michelle J., Falconer, Caitlin, Gassiep, Ian, Norton, Robert E., Paterson, David L. and Harris, Patrick NA (2022). Clinical Burkholderia pseudomallei isolates from north Queensland carry diverse bimABm genes that are associated with central nervous system disease and are phylogenomically distinct from other Australian strains. PLoS Neglected Tropical Diseases, 16 (6) e0009482, 1-12. doi: 10.1371/journal.pntd.0009482
Laupland, Kevin B., Paterson, David L., Stewart, Adam G., Edwards, Felicity and Harris, Patrick N. A. (2022). Sphingomonas paucimobilis bloodstream infection is a predominantly community-onset disease with significant lethality. International Journal of Infectious Diseases, 119, 172-177. doi: 10.1016/j.ijid.2022.03.060
Kwok, Michael, McGeorge, Stephen, Mayer‐Coverdale, Johanna, Graves, Bianca, Paterson, David L., Harris, Patrick N.A., Esler, Rachel, Dowling, Caroline, Britton, Sumudu and Roberts, Matthew J. (2022). Guideline of guidelines: management of recurrent urinary tract infections in women. BJU International, 11 (2), 104-107. doi: 10.1111/bju.15756
Ezure, Yukiko, Rico, Veronica, Paterson, David L., Hall, Lisa, Harris, Patrick N. A., Soriano, Alex, Roberts, Jason A., Bassetti, Matteo, Roberts, Matthew J., Righi, Elda and Wright, Hugh (2022). Efficacy and safety of carbapenems versus new antibiotics for treatment of adult patients with complicated urinary tract infections: a systematic review and meta-analysis. Open Forum Infectious Diseases, 9 (5) ofaa480, ofaa480. doi: 10.1093/ofid/ofaa480
Laupland, Kevin B., Paterson, David L., Edwards, Felicity, Stewart, Adam G. and Harris, Patrick N. A. (2022). Morganella morganii, an emerging cause of bloodstream infections. Microbiology Spectrum, 10 (3), e0056922. doi: 10.1128/spectrum.00569-22
Gassiep, Ian, Bauer, Michelle J., Harris, Patrick N. A. and Norton, Robert (2022). Speed and safety of mass spectrometry for identification of Burkholderia pseudomallei directly from spiked blood cultures. Journal of Medical Microbiology, 71 (4) 001521. doi: 10.1099/jmm.0.001521
Schlebusch, Sanmarié, Graham, Rikki M. A., Jennison, Amy V., Lassig-Smith, Melissa M., Harris, Patrick N. A., Lipman, Jeffrey, Ó Cuív, Páraic and Paterson, David L. (2022). Standard rectal swabs as a surrogate sample for gut microbiome monitoring in intensive care. BMC Microbiology, 22 (1) 99, 1-14. doi: 10.1186/s12866-022-02487-0
Laupland, Kevin B, Stewart, Adam G, Edwards, Felicity, Paterson, David L, Coulter, Sonali, Heney, Claire, George, Narelle and Harris, Patrick (2022). Shewanella spp. bloodstream infections in Queensland, Australia. Emerging Infectious Diseases, 28 (4), 701-706. doi: 10.3201/eid2804.212193
Gassiep, Ian, Bauer, Michelle J., Page, Melissa, Harris, Patrick N. A. and Norton, Robert (2022). Comparative evaluation of Panther Fusion and real-time PCR for detection of Burkholderia pseudomallei in spiked human blood. Access Microbiology, 4 (3) 000333, 1-6. doi: 10.1099/acmi.0.000333
Laupland, Kevin B., Stewart, Adam G., Edwards, Felicity, Harris, Patrick, Heney, Claire, George, Narelle, Coulter, Sonali and Paterson, David L. (2022). Pasteurella species bloodstream infections in Queensland, Australia, 2000–2019. European Journal of Clinical Microbiology and Infectious Diseases, 41 (4), 609-614. doi: 10.1007/s10096-022-04411-w
McNamara, John F, Harris, Patrick NA, Chatfield, Mark D and Paterson, David L (2022). Long term sepsis readmission, mortality and cause of death following Gram negative bloodstream infection: a propensity matched observational linkage study. International Journal of Infectious Diseases, 114, 34-44. doi: 10.1016/j.ijid.2021.10.047
Gassiep, Ian, Ganeshalingam, Vibooshini, Chatfield, Mark D., Harris, Patrick N A and Norton, Robert E. (2022). Melioidosis: laboratory investigations and association with patient outcomes. The American Journal of Tropical Medicine and Hygiene, 106 (1), 54-59. doi: 10.4269/ajtmh.21-0548
Hem, Sopheak, Jarocki, Veronica M., Baker, Dave J., Charles, Ian G., Drigo, Barbara, Aucote, Sarah, Donner, Erica, Burnard, Delaney, Bauer, Michelle J., Harris, Patrick N.A., Wyrsch, Ethan R. and Djordjevic, Steven P. (2022). Genomic analysis of Elizabethkingia species from aquatic environments: evidence for potential clinical transmission. Current Research in Microbial Sciences, 3 100083, 100083. doi: 10.1016/j.crmicr.2021.100083
Peri, Anna Maria, Bauer, Michelle J., Bergh, Haakon, Butkiewicz, Dominika, Paterson, David L. and Harris, Patrick N.A. (2022). Performance of the BioFire Blood Culture Identification 2 Panel for the diagnosis of bloodstream infections on blood cultures from the intensive care unit and emergency department. SSRN Electronic Journal. doi: 10.2139/ssrn.4003859
Cuddihy, Thom, Harris, Patrick N. A., Permana, Budi, Beatson, Scott A. and Forde, Brian M. (2022). CATHAI: cluster analysis tool for healthcare-associated infections. Bioinformatics Advances, 2 (1) vbac040, vbac040. doi: 10.1093/bioadv/vbac040
Isler, Burcu, Aslan, Abdullah Tarık, Akova, Murat, Harris, Patrick and Paterson, David L. (2022). Treatment strategies for OXA-48-like and NDM producing Klebsiella pneumoniae infections. Expert Review of Anti-Infective Therapy, 20 (11), 1389-1400. doi: 10.1080/14787210.2022.2128764
Kwok, Michael, Yaxley, William, Ranasinghe, Sachinka, Morton, Leanne, Perera, Sachin, Ponen, Kreyen, Pelecanos, Anita, Britton, Sumudu, Harris, Patrick N. A., Paterson, David L., Esler, Rachel, Hussey, David, Yaxley, John W. and Roberts, Matthew J. (2022). Determining risk factors for symptomatic urinary tract infection following trial of void: A retrospective analysis. Journal of Clinical Urology, 17 (6), 205141582210998-587. doi: 10.1177/20514158221099856
Stewart, Adam G, Henderson, Andrew, Bauer, Michelle J, Paterson, David L and Harris, Patrick N A (2021). Activity of temocillin against third-generation cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae bloodstream isolates from a clinical trial. JAC-Antimicrobial Resistance, 4 (1) dlab192, dlab192. doi: 10.1093/jacamr/dlab192
Stewart, Adam G., Harris, Patrick N. A., Chatfield, Mark D., Littleford, Roberta and Paterson, David L. (2021). Ceftolozane-tazobactam versus meropenem for definitive treatment of bloodstream infection due to extended-spectrum beta-lactamase (ESBL) and AmpC-producing Enterobacterales (“MERINO-3”): study protocol for a multicentre, open-label randomised non-inferiority trial. Trials, 22 (1) 301, 301. doi: 10.1186/s13063-021-05206-8
Henderson, Andrew, Bursle, Evan, Stewart, Adam, Harris, Patrick N. A., Paterson, David, Chatfield, Mark D., Paul, Mical, Dickstein, Yaakov, Rodriguez-Baño, Jesus, Turnidge, John D. and Kahlmeter, Gunnar (2021). A systematic review of antimicrobial susceptibility testing as a tool in clinical trials assessing antimicrobials against infections due to Gram negative pathogens. Intended category: systematic review. Clinical Microbiology and Infection, 27 (12), 1746-1753. doi: 10.1016/j.cmi.2021.03.019
Wright, Hugh, Harris, Patrick N. A., Chatfield, Mark D., Lye, David, Henderson, Andrew, Harris-Brown, Tiffany, Donaldson, Anna and Paterson, David L. (2021). Investigator-Driven Randomised Controlled Trial of Cefiderocol versus Standard Therapy for Healthcare-Associated and Hospital-Acquired Gram-negative Bloodstream Infection: Study protocol (the GAME CHANGER trial): study protocol for an open-label, randomised controlled trial. Trials, 22 (1) 889. doi: 10.1186/s13063-021-05870-w
Peri, Anna Maria, Harris, Patrick N. A. and Paterson, David L. (2021). Culture-independent detection systems for bloodstream infection. Clinical Microbiology and Infection, 28 (2), 195-201. doi: 10.1016/j.cmi.2021.09.039
Isler, Burcu, Harris, Patrick, Stewart, Adam G. and Paterson, David L. (2021). An update on cefepime and its future role in combination with novel β-lactamase inhibitors for MDR Enterobacterales and Pseudomonas aeruginosa–—authors’ response. Journal of Antimicrobial Chemotherapy, 76 (12), 3327-3328. doi: 10.1093/jac/dkab366
Ling, Weiping, Furuya-Kanamori, Luis, Ezure, Yukiko, Harris, Patrick N. A. and Paterson, David L. (2021). Adverse clinical outcomes associated with carbapenem-resistant Acinetobacter (CRA) infections: a systematic review and meta-analysis. JAC-Antimicrobial Resistance, 3 (4) dlab157, 1-12. doi: 10.1093/jacamr/dlab157
Gassiep, Ian, Ganeshalingam, Vibooshini, Chatfield, Mark D., Harris, Patrick N. A. and Norton, Robert E. (2021). The epidemiology of melioidosis in Townsville, Australia. Transactions of The Royal Society of Tropical Medicine and Hygiene, 116 (4), 328-335. doi: 10.1093/trstmh/trab125
Stewart, Adam G., Paterson, David L., Young, Barnaby, Lye, David C, Davis, Joshua S., Schneider, Kellie, Yilmaz, Mesut, Dinleyici, Rumeysa, Runnegar, Naomi, Henderson, Andrew, Archuleta, Sophia, Kalimuddin, Shirin, Forde, Brian M., Chatfield, Mark D., Bauer, Michelle J., Lipman, Jeffrey, Harris-Brown, Tiffany, Harris, Patrick N. A. and for the MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN) (2021). Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections caused by AmpC beta-lactamase producing Enterobacter spp., Citrobacter freundii, Morganella morganii, Providencia spp., or Serratia marcescens: a pilot multi-center randomized controlled trial (MERINO-2). Open Forum Infectious Diseases, 8 (8) ofab387, ofab387. doi: 10.1093/ofid/ofab387
Elliott, Thomas M., Hurst, Cameron, Doidge, Michelle, Hurst, Trish, Harris, Patrick NA. and Gordon, Louisa G. (2021). Unexpected benefit of COVID-19 hospital restrictions: Reduction in patients isolating with multidrug resistant organisms after restrictions were lifted. Infection, Disease and Health, 27 (1), 10-14. doi: 10.1016/j.idh.2021.08.001
Stewart, Adam G., Cottrell, Kyra, Henderson, Andrew, Vemuri, Kanthi, Bauer, Michelle J., Paterson, David L. and Harris, Patrick N. A. (2021). In vitro activity of Cefotetan against ESBL-producing Escherichia coli and Klebsiella pneumoniae bloodstream isolates from the MERINO Trial. Microbiology Spectrum, 9 (1) e00226-21, 1-6. doi: 10.1128/spectrum.00226-21
Hancock, Steven J., Phan, Minh‐Duy, Roberts, Leah, Vu, Thu Ngoc Minh, Harris, Patrick N.A., Beatson, Scott A. and Schembri, Mark A. (2021). Characterisation of DtrJ as an IncC plasmid conjugative DNA transfer component. Molecular Microbiology, 116 (1), 154-167. doi: 10.1111/mmi.14697
Murigneux, Valentine, Roberts, Leah W., Forde, Brian M., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Irwin, Adam D., Harris, Patrick N. A., Paterson, David L., Schembri, Mark A., Whiley, David M. and Beatson, Scott A. (2021). MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction. BMC Genomics, 22 (1) 474, 474. doi: 10.1186/s12864-021-07767-z
Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680
Gassiep, Ian, Bauer, Michelle J., Harris, Patrick N. A., Chatfield, Mark D. and Norton, Robert (2021). Laboratory safety: handling B. pseudomallei isolates without a biosafety cabinet. Journal of Clinical Microbiology, 59 (7) e0042421, 1-6. doi: 10.1128/jcm.00424-21
Peri, Anna Maria, Stewart, Adam, Hume, Anna, Irwin, Adam and Harris, Patrick N A (2021). New microbiological techniques for the diagnosis of bacterial infections and sepsis in ICU including point of care. Current Infectious Disease Reports, 23 (8) 12, 12. doi: 10.1007/s11908-021-00755-0
Stewart, Adam G., Satlin, Michael J., Schlebusch, Sanmarié, Isler, Burcu, Forde, Brian M., Paterson, David L. and Harris, Patrick N. A. (2021). Completing the picture - capturing the resistome in antibiotic clinical trials. Clinical Infectious Diseases, 72 (12), e1122-e1129. doi: 10.1093/cid/ciaa1877
Stewart, A. G., Price, E. P., Schabacker, K., Birikmen, M., Harris, P. N. A., Choong, K., Subedi, S. and Sarovich, D. S. (2021). Molecular epidemiology of third-generation cephalosporin-resistant Enterobacteriaceae in Southeast Queensland, Australia. Antimicrobial Agents and Chemotherapy, 65 (6) e00130-21, 1-13. doi: 10.1128/AAC.00130-21
Ayfan, Abdulrahman K. S., Macdonald, Joanne, Harris, Patrick N. A., Heney, Claire, Paterson, David L., Trembizki, Ella, Wang, Claire Y. T., Whiley, David M., Zowawi, Hosam M. and Irwin, Adam D. (2021). Rapid detection of NDM and VIM carbapenemase encoding genes by recombinase polymerase amplification and lateral flow–based detection. European Journal of Clinical Microbiology & Infectious Diseases, 40 (11), 2447-2453. doi: 10.1007/s10096-021-04267-6
Ling, Weiping, Furuya-Kanamori, Luis, Ezure, Yukiko, Harris, Patrick N A and Paterson, David L (2021). Adverse clinical outcomes associated with infections by Enterobacterales producing ESBL (ESBL-E): a systematic review and meta-analysis. JAC-Antimicrobial Resistance, 3 (2) dlab068, dlab068. doi: 10.1093/jacamr/dlab068
Ullman, Amanda J., August, Deanne, Kleidon, Tricia, Walker, Rachel, Marsh, Nicole M., Bulmer, Andrew, Pearch, Benjamin, Runnegar, Naomi, Schults, Jessica A., Leema, Joanne, Lee-Archer, Paul, Biles, Cathy, Southam, Katrina, Gibson, Victoria, Byrnes, Joshua, Ware, Robert S., Chopra, Vineet, Coulthard, Alan, Mollee, Peter, Rickard, Claire M. and Harris, Patrick N. A. (2021). Peripherally Inserted Central catheter iNnovation to reduce Infections and Clots (the PICNIC trial): a randomised controlled trial protocol. BMJ Open, 11 (4) e042475, 1-7. doi: 10.1136/bmjopen-2020-042475
Roberts, Leah W., Forde, Brian M., Hurst, Trish, Ling, Weiping, Nimmo, Graeme R., Bergh, Haakon, George, Narelle, Hajkowicz, Krispin, McNamara, John F., Lipman, Jeffrey, Permana, Budi, Schembri, Mark A., Paterson, David, Beatson, Scott A. and Harris, Patrick N. A. (2021). Genomic surveillance, characterization and intervention of a polymicrobial multidrug-resistant outbreak in critical care. Microbial Genomics, 7 (3) 000530. doi: 10.1099/mgen.0.000530
Gassiep, Ian, Burnard, Delaney, Bauer, Michelle J., Norton, Robert E. and Harris, Patrick N. (2021). Diagnosis of melioidosis: the role of molecular techniques. Future Microbiology, 16 (4) fmb-2020-0202, 271-288. doi: 10.2217/fmb-2020-0202
Burnard, Delaney, Robertson, Gemma, Henderson, Andrew, Falconer, Caitlin, Bauer, Michelle J., Cottrell, Kyra, Gassiep, Ian, Norton, Robert, Paterson, David L. and Harris, Patrick N. A. (2021). Burkholderia pseudomallei clinical isolates are highly susceptible in vitro to cefiderocol, a siderophore cephalosporin. Antimicrobial Agents and Chemotherapy, 65 (2) e00685-20. doi: 10.1128/aac.00685-20
Vardanega, John, Maggacis, Raquel, Runnegar, Naomi, Harris, Patrick N.A. and Sehu, Marjoree M. (2021). Discrepancy between VITEK2 and Etest aminoglycoside susceptibility testing for multidrug-resistant Acinetobacter baumannii. Pathology, 53 (6), 1-3. doi: 10.1016/j.pathol.2020.10.021
Paterson, David L., Isler, Burcu and Harris, Patrick N. A. (2021). PRO: Carbapenems should be used for ALL infections caused by ceftriaxone-resistant Enterobacterales. JAC-Antimicrobial Resistance, 3 (1). doi: 10.1093/jacamr/dlab013
Nesporova, Kristina, Wyrsch, Ethan R., Valcek, Adam, Bitar, Ibrahim, Chaw, Khin, Harris, Patrick, Hrabak, Jaroslav, Literak, Ivan, Djordjevic, Steven P. and Dolejska, Monika (2021). Escherichia coli sequence type 457 is an emerging extended-spectrum-β-lactam-resistant lineage with reservoirs in wildlife and food-producing animals. Antimicrobial Agents and Chemotherapy, 65 (1) e01118-20, 1-18. doi: 10.1128/AAC.01118-20
Carrara, Elena, Savoldi, Alessia, Piddock, Laura J. V., Franceschi, Francois, Ellis, Sally, Sharland, Mike, Brink, Adrian John, Harris, Patrick N. A., Levy-Hara, Gabriel, Rohit, Anusha, Tsioutis, Constantinos, Zayyad, Hiba, Giske, Christian, Chiamenti, Margherita, Bragantini, Damiano, Righi, Elda, Gorska, Anna and Tacconelli, Evelina (2021). Clinical management of severe infections caused by carbapenem-resistant gram-negative bacteria: a worldwide cross-sectional survey addressing the use of antibiotic combinations. Clinical Microbiology and Infection, 28 (1), 66-72. doi: 10.1016/j.cmi.2021.05.002
Wijesinghe, Hewa G. S., Hare, Dominic J., Mohamed, Ahmed, Shah, Alok K., Harris, Patrick N. A. and Hill, Michelle M. (2021). Detecting antimicrobial resistance in Escherichia coli using benchtop attenuated total reflectance-Fourier transform infrared spectroscopy and machine learning. The Analyst, 146 (20), 6211-6219. doi: 10.1039/d1an00546d
Elliott, Thomas M., Harris, Patrick N., Roberts, Leah W., Doidge, Michelle, Hurst, Trish, Hajkowicz, Krispin, Forde, Brian, Paterson, David L. and Gordon, Louisa G. (2021). Cost-effectiveness analysis of whole-genome sequencing during an outbreak of carbapenem-resistant Acinetobacter baumannii. Antimicrobial Stewardship and Healthcare Epidemiology, 1 (1) e62, e62. doi: 10.1017/ash.2021.233
Forde, Brian M., De Oliveira, David M. P., Falconer, Caitlin, Graves, Bianca and Harris, Patrick N. A. (2021). Strengths and caveats of identifying resistance genes from whole genome sequencing data. Expert Review of Anti-Infective Therapy, 20 (4), 1-15. doi: 10.1080/14787210.2022.2013806
Isler, Burcu, Harris, Patrick, Stewart, Adam G. and Paterson, David L. (2020). An update on cefepime and its future role in combination with novel β-lactamase inhibitors for MDR Enterobacterales and Pseudomonas aeruginosa. The Journal of Antimicrobial Chemotherapy, 76 (3), 550-560. doi: 10.1093/jac/dkaa511
Gordon, Louisa G., Elliott, Thomas M., Forde, Brian, Mitchell, Brett, Russo, Philip L., Paterson, David L. and Harris, Patrick N. A. (2020). Budget impact analysis of routinely using whole-genomic sequencing of six multidrug-resistant bacterial pathogens in Queensland, Australia. BMJ Open, 11 (2) e041968, e041968. doi: 10.1136/bmjopen-2020-041968
Isler, Burcu, Kidd, Timothy J., Stewart, Adam G., Harris, Patrick and Paterson, David L. (2020). Achromobacter infections and treatment options. Antimicrobial Agents and Chemotherapy, 64 (11) e01025, 1-16. doi: 10.1128/aac.01025-20
Henderson, A., Paterson, D. L., Chatfield, M. D., Tambyah, P. A., Lye, D. C., De, P. P., Lin, R. T. P., Chew, K. L., Yin, M., Lee, T. H., Yilmaz, M., Cakmak, R., Alenazi, T. H., Arabi, Y. M., Falcone, M., Bassetti, M., Righi, E., Rogers, B.A., Kanj, S. S., Bhally, H., Iredell, J., Mendelson, M., Boyles, T. H., Looke, D. F. M., Runnegar, N. J., Miyakis, S., Walls, G., AI Khamis, M., Zikri, A. ... For the MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN) (2020). Association between minimum inhibitory concentration, beta-lactamase genes and mortality for patients treated with piperacillin/tazobactam or meropenem from the MERINO study. Clinical Infectious Diseases, 73 (11), e3842-e3850. doi: 10.1093/cid/ciaa1479
Corley, Amanda, Ullman, Amanda J., Marsh, Nicole, Larsen, Emily N., Mihala, Gabor, Harris, Patrick N.A. and Rickard, Claire M. (2020). SECUREment bundles to prevent peripheral intravenous catheter failure-the SECURE-PIVC trial: Study protocol for a pilot randomized controlled trial. British Journal of Nursing, 29 (19), S40-S46. doi: 10.12968/bjon.2020.29.19.S40
Isler, Burcu, Ezure, Yukiko, García-Fogeda Romero, Jose Luis, Harris, Patrick, Stewart, Adam G. and Paterson, David L. (2020). Is ceftazidime/avibactam an option for serious infections due to ESBL and AmpC producing Enterobacterales?: a systematic review and meta-analysis. Antimicrobial Agents and Chemotherapy, 65 (1) e01052-20. doi: 10.1128/AAC.01052-20
McNamara, John F., Harris, Patrick N. A., Chatfield, Mark D. and Paterson, David L. (2020). Reply to Rezahosseini and Nielsen. Clinical Infectious Diseases, 72 (11), e916-e916. doi: 10.1093/cid/ciaa1449
Burnard, Delaney, Gore, Letitia, Henderson, Andrew, Ranasinghe, Ama, Bergh, Haakon, Cottrell, Kyra, Sarovich, Derek S., Price, Erin P., Paterson, David L. and Harris, Patrick N. A. (2020). Comparative genomics and antimicrobial resistance profiling of Elizabethkingia isolates reveals nosocomial transmission and in vitro susceptibility to fluoroquinolones, tetracyclines and trimethoprim-sulfamethoxazole. Journal of Clinical Microbiology, 58 (9) e00730-20. doi: 10.1128/jcm.00730-20
Sumi, Chandra Datta, Heffernan, Aaron J., Naicker, Saiyuri, Islam, Kamrul, Cottrell, Kyra, Wallis, Steven C., Lipman, Jeffrey, Harris, Patrick N. A., Sime, Fekade B. and Roberts, Jason A. (2020). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae. Journal of Antimicrobial Chemotherapy, 75 (9), 2633-2640. doi: 10.1093/jac/dkaa211
McNamara, John F., Harris, Patrick N. A., Chatfield, Mark D. and Paterson, David L. (2020). Acute myocardial infarction and community-acquired Staphylococcus aureus bloodstream infection: an observational cohort study. Clinical Infectious Diseases, 73 (9), e2647-e2655. doi: 10.1093/cid/ciaa1197
Roberts, Matthew J., Macdonald, Alastair, Ranasinghe, Sachinka, Bennett, Harrison, Teloken, Patrick E., Harris, Patrick, Paterson, David, Coughlin, Geoff, Dunglison, Nigel, Esler, Rachel, Gardiner, Robert A., Elliott, Thomas, Gordon, Louisa and Yaxley, John (2020). Transrectal versus transperineal prostate biopsy under intravenous anaesthesia: a clinical, microbiological and cost analysis of 2048 cases over 11 years at a tertiary institution. Prostate Cancer and Prostatic Diseases, 24 (1), 169-176. doi: 10.1038/s41391-020-0263-x
Wang, Claire Y.T., Buckley, Cameron, Bletchly, Cheryl, Harris, Patrick and Whiley, David (2020). Contamination of SARS-CoV-2 RT-PCR probes at the oligonucleotide manufacturer. Pathology, 52 (7), 814-816. doi: 10.1016/j.pathol.2020.08.002
Stewart, Adam G., Harris, Patrick N. A., Chatfield, Mark, Evans, Scott R., van Duin, David and Paterson, David L. (2020). Modern clinician-initiated clinical trials to determine optimal therapy for multi-drug resistant Gram-negative infections. Clinical Infectious Diseases, 71 (2), 433-439. doi: 10.1093/cid/ciz1132
Heffernan, Aaron J., Sime, Fekade B., Sarovich, Derek S., Neely, Michael, Guerra-Valero, Yarmarly, Naicker, Saiyuri, Cottrell, Kyra, Harris, Patrick, Andrews, Katherine T., Ellwood, David, Wallis, Steven C., Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2020). Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model. Antimicrobial Agents and Chemotherapy, 64 (9) e00879-20. doi: 10.1128/aac.00879-20
De Oliveira, David M. P., Forde, Brian M., Kidd, Timothy J., Harris, Patrick N. A., Schembri, Mark A., Beatson, Scott A., Paterson, David L. and Walker, Mark J. (2020). Antimicrobial resistance in ESKAPE pathogens. Clinical Microbiology Reviews, 33 (3) e00181-19, e00181-19. doi: 10.1128/cmr.00181-19
Stewart, Adam G., Harris, Patrick N. A., Henderson, Andrew, Schembri, Mark A. and Paterson, David L. (2020). Oral cephalosporin and β-lactamase inhibitor combinations for ESBL-producing Enterobacteriaceae urinary tract infections. Journal of Antimicrobial Chemotherapy, 75 (9), 2384-2393. doi: 10.1093/jac/dkaa183
Chapman, Paul, Forde, Brian M., Roberts, Leah W., Bergh, Haakon, Vesey, Debra, Jennison, Amy V., Moss, Susan, Paterson, David L., Beatson, Scott A. and Harris, Patrick N. A. (2020). Genomic investigation reveals contaminated detergent as the source of an Extended-Spectrum-β-Lactamase-producing Klebsiella michiganensis outbreak in a neonatal unit. Journal of Clinical Microbiology, 58 (5) e01980. doi: 10.1128/jcm.01980-19
Harris, Patrick N. A. and Wailan, Alexander M. (2020). Beyond the Core Genome: Tracking Plasmids in Outbreaks of Multidrug-resistant Bacteria. Clinical Infectious Diseases, 72 (3), 421-422. doi: 10.1093/cid/ciaa052
Paterson, David L., Henderson, Andrew and Harris, Patrick N. A. (2020). Current evidence for therapy of ceftriaxone-resistant Gram-negative bacteremia. Current Opinion in Infectious Diseases, 33 (1), 78-85. doi: 10.1097/QCO.0000000000000623
McNamara, J. F., Harris, P. N. A., Chatfield, M. D., Lorenc, P. and Paterson, D. L. (2020). Measuring patient-centred long-term outcome following a bloodstream infection: a pilot study. Clinical Microbiology and Infection, 26 (2), 257.e1-257.e4. doi: 10.1016/j.cmi.2019.10.011
Roberts, Leah W., Harris, Patrick N. A., Forde, Brian M., Ben Zakour, Nouri L., Catchpoole, Elizabeth, Stanton-Cook, Mitchell, Phan, Minh-Duy, Sidjabat, Hanna E., Bergh, Haakon, Heney, Claire, Gawthorne, Jayde A., Lipman, Jeffrey, Allworth, Anthony, Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Schembri, Mark A., Paterson, David L. and Beatson, Scott A. (2020). Integrating multiple genomic technologies to investigate an outbreak of carbapenemase-producing Enterobacter hormaechei. Nature Communications, 11 (1) 466, 466. doi: 10.1038/s41467-019-14139-5
Elliott, Thomas M., Lee, Xing J., Foeglein, Anna, Harris, Patrick N. and Gordon, Louisa G. (2020). A hybrid simulation model approach to examine bacterial genome sequencing during a hospital outbreak. BMC Infectious Diseases, 20 (1) 72, 72. doi: 10.1186/s12879-019-4743-3
Denny, K. J., De Waele, J., Laupland, K. B., Harris, P. N.A. and Lipman, J. (2020). Erratum to ‘When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit’ [Clin Microbiol Infect 26 (1) (January 2020) 35–40](S1198743X19303969)(10.1016/j.cmi.2019.07.007). Clinical Microbiology and Infection, 26 (6), 801-801. doi: 10.1016/j.cmi.2020.01.016
Vickers, Mark L., Ballard, Emma L., Harris, Patrick N. A., Knibbs, Luke D., Jaiprakash, Anjali, Dulhunty, Joel M., Crawford, Ross W. and Parkinson, Benjamin (2020). Bacterial profile, multi-drug resistance and seasonality following lower limb orthopaedic surgery in tropical and subtropical Australian hospitals: an epidemiological cohort study. International Journal of Environmental Research and Public Health, 17 (2) 657, 1-15. doi: 10.3390/ijerph17020657
Denny, K. J., De Waele, J., Laupland, K. B., Harris, P. N. A. and Lipman, J. (2020). When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit. Clinical Microbiology and Infection, 26 (1), 35-40. doi: 10.1016/j.cmi.2019.07.007
Lee, Xing J., Elliott, Thomas M., Harris, Patrick N. A., Douglas, Joel, Henderson, Belinda, Watson, Catherine, Paterson, David L., Schofield, Deborah S., Graves, Nicholas and Gordon, Louisa G. (2020). Clinical and Economic Outcomes of Genome Sequencing Availability on Containing a Hospital Outbreak of Resistant Escherichia coli in Australia. Value in Health, 23 (8), 994-1002. doi: 10.1016/j.jval.2020.03.006
Elliott, Thomas M., Hare, Nicole, Hajkowicz, Krispin, Hurst, Trish, Doidge, Michelle, Harris, Patrick N. and Gordon, Louisa G. (2020). Evaluating the economic effects of genomic sequencing of pathogens to prioritise hospital patients competing for isolation beds. Australian Health Review, 45 (1), 59-65. doi: 10.1071/AH20071
Roberts, Leah W., Catchpoole, Elizabeth, Jennison, Amy V., Bergh, Haakon, Hume, Anna, Heney, Claire, George, Narelle, Paterson, David L., Schembri, Mark A., Beatson, Scott A. and Harris, Patrick N. A. (2019). Genomic analysis of carbapenemase-producing Enterobacteriaceae in Queensland reveals widespread transmission of blaIMP-4 on an IncHI2 plasmid. Microbial Genomics, 6 (1) 000321. doi: 10.1099/mgen.0.000321
Henderson, A., Harris, P., Hartel, G., Paterson, D., Turnidge, J., Davis, J. S. and Tong, S. Y. C. (2019). Benzylpenicillin versus flucloxacillin for penicillin susceptible Staphylococcus aureus bloodstream infections from a large retrospective cohort study. International Journal of Antimicrobial Agents, 54 (4), 491-495. doi: 10.1016/j.ijantimicag.2019.05.020
Fraser, Tamieka A., Bell, Mikaela G., Harris, Patrick N. A., Bell, Scott C., Bergh, Haakon, Thuy-Khanh Nguyen,, Kidd, Timothy J., Nimmo, Graeme R., Sarovich, Derek S. and Price, Erin P. (2019). Quantitative real-time PCR assay for the rapid identification of the intrinsically multidrug-resistant bacterial pathogen Stenotrophomonas maltophilia. Microbial Genomics, 5 (10) 000307. doi: 10.1099/mgen.0.000307
Vickers, Mark L., Malacova, Eva, Milinovich, Gabriel J., Harris, Patrick, Eriksson, Lars, Dulhunty, Joel M. and Cotta, Menino O. (2019). Modifiable risk factors for multidrug-resistant Gram-negative infection in critically ill burn patients: a systematic review and meta-analysis. ANZ Journal of Surgery, 89 (10) ans.15393, 1256-1260. doi: 10.1111/ans.15393
Huber, Charlotte A, Pflüger, Valentin, Reed, Sarah, Cottrell, Kyra, Sidjabat, Hanna E, Ranasinghe, Ama, Zowawi, Hosam, Harris, Patrick and Paterson, David L (2019). Bacterial identification using an Absciex 5800 TOF/TOF MALDI research instrument and an external database. Journal of Microbiological Methods, 164 105685, 105685. doi: 10.1016/j.mimet.2019.105685
Bordin, Amanda, Trembizki, Ella, Windsor, Madeline, Wee, Rachel, Tan, Lit Yeen, Buckley, Cameron, Syrmis, Melanie, Bergh, Haakon, Cottrell, Kyra, Zowawi, Hosam M., Sidjabat, Hanna E, Harris, Patrick N. A., Nimmo, Graeme R., Paterson, David L. and Whiley, David M. (2019). Evaluation of the SpeeDx Carba (beta) multiplex real-time PCR assay for detection of NDM, KPC, OXA-48-like, IMP-4-like and VIM carbapenemase genes. BMC Infectious Diseases, 19 (1) 571, 571. doi: 10.1186/s12879-019-4176-z
Cheng, Matthew P., Lee, Robyn S., Cheng, Alexandre P., De L'étoile-Morel, Samuel, Demir, Koray, Yansouni, Cedric P., Harris, Patrick, Mcdonald, Emily G. and Lee, Todd C. (2019). Beta-lactam/beta-lactamase inhibitor therapy for potential AmpC-producing organisms: a systematic review and meta-analysis. Open Forum Infectious Diseases, 6 (7) ofz248. doi: 10.1093/ofid/ofz248
Harris, Patrick N. A. (2019). By ZEUS!: can we use intravenous fosfomycin for complicated urinary tract infections?. Clinical Infectious Diseases, 69 (12), 2057-2058. doi: 10.1093/cid/ciz185
Vickers, Mark L., Pelecanos, Anita, Tran, Marie, Eriksson, Lars, Assoum, Mohamad, Harris, Patrick N., Jaiprakash, Anjali, Parkinson, Benjamin, Dulhunty, Joel and Crawford, Ross W. (2019). Association between higher ambient temperature and orthopaedic infection rates: a systematic review and meta-analysis. ANZ Journal of Surgery, 89 (9) ans.15089, 1028-1034. doi: 10.1111/ans.15089
Harris, Patrick N. A., Tambyah, Paul and Paterson, David L. (2019). Antibiotics for ceftriaxone resistant gram-negative bacterial bloodstream infections-reply. The Journal of the American Medical Association, 321 (6), 613-614. doi: 10.1001/jama.2018.19353
Koulenti, Despoina, Song, Andrew, Ellingboe, Aaron, Abdul-Aziz, Mohd Hafiz, Harris, Patrick, Gavey, Emile and Lipman, Jeffrey (2019). Infections by multidrug-resistant gram-negative bacteria: what's new in our arsenal and what's in the pipeline?. International Journal of Antimicrobial Agents, 53 (3), 211-224. doi: 10.1016/j.ijantimicag.2018.10.011
Roberts, M. J., Scott, S., Harris, P. N., Naber, K., Wagenlehner, F. M.E. and Doi, S. A.R. (2019). Re: Comparison of Fosfomycin against Fluoroquinolones for Transrectal Prostate Biopsy Prophylaxis: An Individual Patient-Data Meta-Analysis. Journal of Urology, 201 (5), 839-840. doi: 10.1016/j.juro.2018.05.090
Peri, Anna Maria, Doi, Yohei, Potoski, Brian A., Harris, Patrick N.A., Paterson, David L. and Righi, Elda (2019). Antimicrobial treatment challenges in the era of carbapenem resistance. Diagnostic Microbiology and Infectious Disease, 94 (4), 413-425. doi: 10.1016/j.diagmicrobio.2019.01.020
Avent, Minyon L., Rogers, Benjamin A., Cheng, Allen C., Athan, Eugene, Francis, Joshua R., Roberts, Matthew J., Paterson, David L. and Harris, Patrick N. A. (2018). Fosfomycin: what was old is new again. Internal Medicine Journal, 48 (12), 1425-1429. doi: 10.1111/imj.14122
Paterson, David L., Wright, Hugh and Harris, Patrick N.A. (2018). Health risks of flood disasters. Clinical Infectious Diseases, 67 (9), 1450-1454. doi: 10.1093/cid/ciy227
Sukumaran, Vichitra, Roberts, Matthew J. and Harris, Patrick N. A. (2018). Infectious complications following transrectal ultrasound-guided prostate biopsy: what additional diagnostic value do blood cultures provide?. Infectious Diseases, 50 (11-12), 1-3. doi: 10.1080/23744235.2018.1508886
Forde, Brian M., Zowawi, Hosam M., Harris, Patrick N. A., Roberts, Leah, Ibrahim, Emad, Shaikh, Nissar, Deshmukh, Anand, Sid Ahmed, Mazen A., Al Maslamani, Muna, Cottrell, Kyra, Trembizki, Ella, Sundac, Lana, Yu, Heidi H., Li, Jian, Schembri, Mark A., Whiley, David M., Paterson, David L. and Beatson, Scott A. (2018). Discovery of mcr-1-mediated colistin resistance in a highly virulent Escherichia coli lineage. mSphere, 3 (5) e00486-18. doi: 10.1128/msphere.00486-18
Harris, Patrick N. A., Tambyah, Paul A., Lye, David C., Mo, Yin, Lee, Tau H., Yilmaz, Mesut, Alenazi, Thamer H., Arabi, Yaseen, Falcone, Marco, Bassetti, Matteo, Righi, Elda, Rogers, Benjamin A., Kanj, Souha, Bhally, Hasan, Iredell, Jon, Mendelson, Marc, Boyles, Tom H., Looke, David, Miyakis, Spiros, Walls, Genevieve, Al Khamis, Mohammed, Zikri, Ahmed, Crowe, Amy, Ingram, Paul, Daneman, Nick, Griffin, Paul, Athan, Eugene, Lorenc, Penelope, Baker, Peter ... MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN) (2018). Effect of piperacillin-tazobactam vs meropenem on 30-day mortality for patients with E coli or Klebsiella pneumoniae bloodstream infection and ceftriaxone resistance: a randomized clinical trial. JAMA, 320 (10), 984-994. doi: 10.1001/jama.2018.12163
Stewart, Adam, Harris, Patrick, Henderson, Andrew and Paterson, David (2018). Treatment of infections with OXA-48 producing Enterobacteriaceae. Antimicrobial Agents and Chemotherapy, 62 (11) e01195-18, AAC.01195-18. doi: 10.1128/aac.01195-18
McNamara, John F., Righi, Elda, Wright, Hugh, Hartel, Gunter F., Harris, Patrick N. A. and Paterson, David L. (2018). Long-term morbidity and mortality following bloodstream infection: a systematic literature review. The Journal of Infection, 77 (1), 1-8. doi: 10.1016/j.jinf.2018.03.005
Scott, Susan, Harris, Patrick N., Williamson, Deborah A., Liss, Michael A., Doi, Suhail A. R. and Roberts, Matthew J. (2018). The effectiveness of targeted relative to empiric prophylaxis on infectious complications after transrectal ultrasound-guided prostate biopsy: a meta-analysis. World Journal of Urology, 36 (7), 1007-1017. doi: 10.1007/s00345-018-2217-7
Djoko, Karrera Y., Achard, Maud E. S., Phan, Minh-Duy, Lo, Alvin W., Miraula, Manfredi, Prombhul, Sasiprapa, Hancock, Steven J., Peters, Kate M., Sidjabat, Hanna E., Harris, Patrick N., Mitić, Nataša, Walsh, Timothy R., Anderson, Gregory J., Shafer, William M., Paterson, David L., Schenk, Gerhard, McEwan, Alastair G. and Schembri, Mark A. (2018). Copper ions and coordination complexes as novel carbapenem adjuvants. Antimicrobial Agents and Chemotherapy, 62 (2) e02280-17. doi: 10.1128/AAC.02280-17
Pang, Long, Harris, Patrick N. A., Seiler, Rachel L., Ooi, Peng Lim, Cutter, Jeffrey, Goh, Kee Tai, Cook, Alex R., Fisher, Dale and Chai, Louis Yi Ann (2018). Melioidosis, Singapore, 2003–2014. Emerging Infectious Diseases, 24 (1), 140-143. doi: 10.3201/eid2401.161449
Roberts, Matthew J, Scott, Susan, Harris, Patrick N, Naber, Kurt, Wagenlehner, Florian M E and Doi, Suhail A R (2017). Comparison of fosfomycin against fluoroquinolones for transrectal prostate biopsy prophylaxis: an individual patient-data meta-analysis. World journal of urology, 36 (3), 323-330. doi: 10.1007/s00345-017-2163-9
Harris, Patrick N. A., Ben Zakour, Nouri L., Roberts, Leah W., Wailan, Alexander M., Zowawi, Hosam M., Tambyah, Paul A., Lye, David C., Jureen, Roland, Lee, Tau H., Yin, Mo, Izharuddin, Ezlyn, Looke, David, Runnegar, Naomi, Rogers, Benjamin, Bhally, Hasan, Crowe, Amy, Schembri, Mark A., Beatson, Scott A. and Paterson, David L. (2017). Whole genome analysis of cephalosporin-resistant Escherichia coli from bloodstream infections in Australia, New Zealand and Singapore: high prevalence of CMY-2 producers and ST131 carrying blaCTX-M-15 and blaCTX-M-27. The Journal of Antimicrobial Chemotherapy, 73 (3), 634-642. doi: 10.1093/jac/dkx466
Harris, Patrick N. A., Pezzani, M. Diletta, Gutierrez-Gutierrez, Belen, Viale, Pierluigi, Hsueh, Po-Ren, Ruiz-Garbajosa, Patricia, Venditti, Mario, Tumbarello, Mario, Navarro-Francisco, Carolina, Calbo, Esther, Akova, Murat, Giamarellou, Helen, Oliver, Antonio, Almirante, Benito, Gasch, Oriol, Martinez-Martinez, Luis, Schwaber, Mitchell J., Daikos, George, Pitout, Johann, Pena, Carmen, Hernandez-Torres, Alicia, Doi, Yohei, Perez, Federico, Tuon, Felipe Francisco, Tacconelli, Evelina, Carmeli, Yehuda, Bonomo, Robert A., Pascual, Alvaro, Paterson, David L. and Rodriguez-Bano, Jesus (2017). Geographical variation in therapy for bloodstream infections due to multidrug-resistant Enterobacteriaceae: a post-hoc analysis of the INCREMENT study. International Journal of Antimicrobial Agents, 50 (5), 664-672. doi: 10.1016/j.ijantimicag.2017.08.005
Harris, P.N.A., McNamara, J.F., Lye, D.C., Davis, J.S., Bernard, L., Cheng, A.C., Doi, Y., Fowler, V.G., Kaye, K.S., Leibovici, L., Lipman, J., Llewelyn, M.J., Munoz-Price, S., Paul, M., Peleg, A.Y., Rodriguez-Bano, J., Rogers, B.A., Seifert, H., Thamlikitkul, V., Thwaites, G., Tong, S.Y.C., Turnidge, J., Utili, R., Webb, S.A.R. and Paterson, D.L. (2017). Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition. Clinical Microbiology and Infection, 23 (8), 533-541. doi: 10.1016/j.cmi.2016.10.023
Webster, J., Larsen, E., Marsh, N., Choudhury, A., Harris, P. and Rickard, C. M. (2017). Chlorhexidine gluconate or polyhexamethylene biguanide disc dressing to reduce the incidence of central-line-associated bloodstream infection: a feasibility randomized controlled trial (the CLABSI trial). Journal of Hospital Infection, 96 (3), 223-228. doi: 10.1016/j.jhin.2017.04.009
Righi, Elda, Peri, Anna Maria, Harris, Patrick N. A., Wailan, Alexander M., Liborio, Mariana, Lane, Steven W. and Paterson, David L. (2017). Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis. Journal of Antimicrobial Chemotherapy, 72 (3), 668-677. doi: 10.1093/jac/dkw459
Harris, Patrick N. A., Peri, Anna M., Pelecanos, Anita M., Hughes, Carly M., Paterson, David L. and Ferguson, John K. (2017). Risk factors for relapse or persistence of bacteraemia caused by Enterobacter spp.: a case-control study. Antimicrobial Resistance and Infection Control, 6 (1) 14, 14. doi: 10.1186/s13756-017-0177-0
Roberts, Matthew J., Bennett, Harrison Y., Harris, Patrick N., Holmes, Michael, Grummet, Jeremy, Naber, Kurt and Wagenlehner, Florian M. E. (2016). Prostate biopsy-related infection: a systematic review of risk factors, prevention strategies, and management approaches. Urology, 104, 11-21. doi: 10.1016/j.urology.2016.12.011
Huber, Charlotte A., Sidjabat, Hanna E., Zowawi, Hosam M., Kvaskoff, David, Reed, Sarah, McNamara, John F., McCarthy, Kate L., Harris, Patrick, Toh, Benjamin, Wailan, Alexander M. and Paterson, David L. (2016). Detection of carbapenemase activity in Enterobacteriaceae using LC-MS/MS in comparison with the neo-rapid CARB kit using direct visual assessment and colorimetry. Journal of Microbiological Methods, 131, 68-72. doi: 10.1016/j.mimet.2016.10.005
Rafiei, Nastaran, Peri, Anna Maria, Righi, Elda, Harris, Patrick and Paterson, David L. (2016). Central nervous system nocardiosis in Queensland: a report of 20 cases and review of the literature. Medicine, 95 (46) e5255, e5255. doi: 10.1097/MD.0000000000005255
Harris, Patrick N. A., Oltvolgyi, Csongor, Islam, Aminul, Hussain-Yusuf, Hazizul, Loewenthal, Mark R., Vincent, Gemma, Stenos, John and Graves, Stephen (2016). An outbreak of scrub typhus in military personnel despite protocols for antibiotic prophylaxis: doxycycline resistance excluded by a quantitative PCR-based susceptibility assay. Microbes and Infection, 18 (6), 406-411. doi: 10.1016/j.micinf.2016.03.006
Ng, Tat Ming, Khong, Wendy X., Harris, Patrick N. A., De, Partha P., Chow, Angela, Tambyah, Paul A. and Lye, David C. (2016). Empiric piperacillin-tazobactam versus carbapenems in the treatment of bacteraemia due to extended-spectrum beta-lactamase-producing enterobacteriaceae. Plos One, 11 (4) e0153696, e0153696. doi: 10.1371/journal.pone.0153696
Paterson, David L. and Harris, Patrick N. A. (2016). Colistin resistance: a major breach in our last line of defence. The Lancet Infectious Diseases, 16 (2), 132-133. doi: 10.1016/S1473-3099(15)00463-6
Harris, Patrick N. A., Wei, Jane Y., Shen, Andrew W., Abdile, Ahmed A., Paynter, Stuart, Huxley, Rachel R., Pandeya, Nirmala, Doi, Yohei, Huh, Kyungmin, O'Neal, Catherine S., Talbot, Thomas R. and Paterson, David L. (2016). Carbapenems versus alternative antibiotics for the treatment of bloodstream infections caused by Enterobacter, Citrobacter or Serratia species: a systematic review with meta-analysis. Journal of Antimicrobial Chemotherapy, 71 (2) dkv346, 296-306. doi: 10.1093/jac/dkv346
Zowawi, Hosam M., Harris, Patrick N. A., Roberts, Matthew J., Tambyah, Paul A., Schembri, Mark A., Pezzani, M. Diletta, Williamson, Deborah A. and Paterson, David L. (2015). The emerging threat of multidrug-resistant Gram-negative bacteria in urology. Nature Reviews Urology, 12 (10), 570-584. doi: 10.1038/nrurol.2015.199
Khatri, Asma, Murphy, Nina Naeger, Wiest, Peter, Osborn, Melissa, Garber, Kathleen, Hecker, Michelle, Hurless, Kelly, Rudin, Susan D., Jacobs, Michael R., Kalayjian, Robert C., Salata, Robert A., Van Duin, David, Perez, Federico, Bonomob, Robert A., Paterson, David L. and Harris, Patrick N. A. (2015). Community-acquired pyelonephritis in pregnancy caused by KPC-producing Klebsiella pneumoniae. Antimicrobial Agents and Chemotherapy, 59 (8), 4375-4378. doi: 10.1128/AAC.00553-15
Paterson, David L. and Harris, Patrick N. A. (2015). Editorial commentary: the new acinetobacter equation: hypervirulence plus antibiotic resistance equals big trouble. Clinical Infectious Diseases, 61 (2), 155-156. doi: 10.1093/cid/civ227
Harris, P. N. A., Alder, L. and Paterson, D. L. (2015). Antimicrobial susceptibility reporting and treatment selection for AmpC-producing Enterobacteriaceae: what do microbiologists and infectious disease practitioners actually practice?. Pathology, 47 (4), 386-388. doi: 10.1097/PAT.0000000000000255
Harris, Patrick N. A., Yin, Mo, Jureen, Roland, Chew, Jonathan, Ali, Jaminah, Paynter, Stuart, Paterson, David L. and Tambyah, Paul A. (2015). Comparable outcomes for β-lactam/β-lactamase inhibitor combinations and carbapenems in definitive treatment of bloodstream infections caused by cefotaxime-resistant Escherichia coli or Klebsiella pneumoniae. Antimicrobial Resistance and Infection Control, 4 (1) 14, 14.1-14.10. doi: 10.1186/s13756-015-0055-6
Harris, Patrick, Paterson, David and Rogers, Benjamin (2015). Facing the challenge of multidrug-resistant gram-negative bacilli in Australia. Medical Journal of Australia, 202 (5), 243-246. doi: 10.5694/mja14.01257
Harris, Patrick N. A., Le, Bich Diep, Tambyah, Paul, Hsu, Li Yang, Pada, Surinder, Archuleta, Sophia, Salmon, Sharon, Mukhopadhyay, Amartya, Dillon, Jasmine, Ware, Robert and Fisher, Dale A. (2015). Antiseptic body washes for reducing the transmission of methicillin-resistant Staphylococcus aureus: A cluster crossover study. Open Forum Infectious Diseases, 2 (2) ofv051, ofv051. doi: 10.1093/ofid/ofv051
Harris, Patrick N. A., Peleg, Anton Y., Iredell, Jon, Ingram, Paul R., Miyakis, Spiros, Stewardson, Andrew J., Rogers, Benjamin A., McBryde, Emma S., Roberts, Jason A., Lipman, Jeff, Athan, Eugene, Paul, Sanjoy K., Baker, Peter, Harris-Brown, Tiffany and Paterson, David L. (2015). Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp (the MERINO trial): study protocol for a randomised controlled trial. Trials, 16 (1) 24, 24.1-24.8. doi: 10.1186/s13063-014-0541-9
Harris, Patrick N. A. (2015). Clinical management of infections caused by enterobacteriaceae that express extended-spectrum β-Lactamase and AmpC enzymes. Seminars in Respiratory and Critical Care Medicine, 36 (1), 56-73. doi: 10.1055/s-0034-1398387
Harris, Patrick N. A., Tambyah, Paul A. and Paterson, David L. (2015). β-lactam and β-lactamase inhibitor combinations in the treatment of extended-spectrum β-lactamase producing Enterobacteriaceae: Time for a reappraisal in the era of few antibiotic options?. The Lancet Infectious Diseases, 15 (4), 475-485. doi: 10.1016/S1473-3099(14)70950-8
Harris, Patrick N. A., Wang, Alvin D., Yin, Mo, Lee, Chun Kiat and Archuleta, Sophia (2014). Atypical hand, foot, and mouth disease: eczema coxsackium can also occur in adults. Lancet Infectious Diseases, 14 (11), 1043-1043. doi: 10.1016/S1473-3099(14)70976-4
Ingram, P. R., Murray, Ronan J., Cheng, Allen C., Blyth, C. C., Walls, Tony, Fisher, D. A., Davis, Josh S., Abbott, Iain, Kanapathipillai, Rupa, Madigan, Victoria, McLellan, Duncan, Briggs, Simon, King, Claire, Hurley, James, Lim, Lyn-Li, Kennedy, Karina, Wilson, Heather, Evans, Thomas, Maze, Michael, Pithie, Alan, Chong, Lauren, Leung, Grace, McCann, Sarah, Lee, Lai-yang, Wolfgang, Jill, Day, Thomas, Silva, Gustinna De, Martinello, Marianne, Gliddon, Thomas ... on behalf of the Australasian Society for Infectious Diseases Clinical Research Network (2014). What do infectious diseases physicians do? A 2-week snapshot of inpatient consultative activities across Australia, New Zealand and Singapore. Clinical Microbiology and Infection, 20 (10), O737-O744. doi: 10.1111/1469-0691.12581
Fisher, Dale A. and Harris, Patrick N. A. (2014). Melioidosis: refining management of a tropical time bomb. The Lancet, 383 (9919), 762-764. doi: 10.1016/S0140-6736(13)62143-1
Harris, P., Eales, K. M., Squires, R., Govan, B. and Norton, R. (2013). Acute Q fever in northern Queensland: variation in incidence related to rainfall and geographical location. Epidemiology and Infection, 141 (5), 1034-1038. doi: 10.1017/S0950268812001495
Harris, P. N. A. and Ferguson, J. K. (2012). Antibiotic therapy for inducible AmpC β-lactamase-producing Gram-negative bacilli: what are the alternatives to carbapenems, quinolones and aminoglycosides?. International Journal of Antimicrobial Agents, 40 (4), 297-305. doi: 10.1016/j.ijantimicag.2012.06.004
Harris, Patrick N. A., Ashhurst-Smith, Chris, Berenger, Sandy J. and Ferguson, John K. (2012). Adhesive tape in the health care setting: another high-risk fomite?. Medical Journal of Australia, 196 (1), 34-34. doi: 10.5694/mja11.11211
Harris, Patrick, Winney, Ian, Ashhurst-Smith, Chris, O'Brien, Mark and Graves, Stephen (2012). Comparison of Vitek MS (MALDI-TOF) to standard routine identification methods: an advance but no panacea. Pathology, 44 (6), 583-585. doi: 10.1097/PAT.0b013e328358343c
Harris, P., Dixit, R. and Norton, R. (2011). Coxiella burnetii causing haemophagocytic syndrome: a rare complication of an unusual pathogen. Infection, 39 (6), 579-582. doi: 10.1007/s15010-011-0142-4
Norton, R., Harris, P. and Senthuran, S. (2011). Reply. Internal Medicine Journal, 41 (9), 710-710. doi: 10.1111/j.1445-5994.2011.02558.x
Harris, Patrick N. A., Williams, Natasha L., Morris, Jodie L., Ketheesan, Natkunam and Norton, Robert E. (2011). Evidence of Burkholderia pseudomallei-specific immunity in patient sera persistently nonreactive by the indirect hemagglutination assay. Clinical and Vaccine Immunology, 18 (8), 1288-1291. doi: 10.1128/CVI.00077-11
Harris, P., Siew, D-A., Proud, M., Buettner, P. and Norton, R. (2011). Bacteraemia caused by beta-haemolytic streptococci in North Queensland: changing trends over a 14-year period. Clinical Microbiology and Infection, 17 (8), 1216-1222. doi: 10.1111/j.1469-0691.2010.03427.x
Cheong, Jenny Wan Sai, Harris, Patrick, Oman, Kimberly and Norton, Robert (2011). Challenges in the microbiological diagnosis and management of hVISA infections. Pathology, 43 (4), 357-361. doi: 10.1097/PAT.0b013e3283464ca3
Harris, Patrick, Engler, Cathy and Norton, Robert (2011). Comparative in vitro susceptibility of Burkholderia pseudomallei to doripenem, ertapenem, tigecycline and moxifloxacin. International Journal of Antimicrobial Agents, 37 (6), 547-549. doi: 10.1016/j.ijantimicag.2011.02.001
Harris, P., Price, S., Senthuran, S., Cochupanachimootil, J. and Norton, R. (2011). Automated erythrocytapheresis for severe falciparum malaria. Internal Medicine Journal, 41 (1A), 60-63. doi: 10.1111/j.1445-5994.2010.02362.x
Norton, Robert, Harris, Patrick, Ryan, Pat and Simpson, Scott (2010). Another killer of the Australian Bush: a rapidly fatal meningoencephalitis in a child. Clinical Infectious Diseases, 50 (10), 1375-1376. doi: 10.1086/652146
Douglas, A., Harris, P., Francis, F. and Norton, R. (2010). Herpes zoster meningoencephalitis: Not only a disease of the immunocompromised?. Infection, 38 (1), 73-75. doi: 10.1007/s15010-009-9092-5
Harris, Patrick N., Dixit, Rashmi, Francis, Fleur, Buettner, Petra G., Leahy, Clinton, Burgher, Bjorn, Egan, Angela, Proud, Michelle, Jayalath, Ruvinka, Grewal, Amrit and Norton, Robert E. (2010). Pandemic influenza H1N1 2009 in north Queensland – risk factors for admission in a region with a large indigenous population.. Communicable Diseases Intelligence Quarterly Report, 34 (2), 102-109.
Harris, Patrick N. A., Ketheesan, Natkunam, Owens, Leigh and Norton, Robert E. (2009). Clinical features that affect indirect-hemagglutination-assay responses to Burkholderia pseudomallei. Clinical and Vaccine Immunology, 16 (6), 924-930. doi: 10.1128/CVI.00026-09

Conference Papers

Gassiep, Ian, Burnard, Delaney, Permana, Budi, Bauer, Michelle J., Cuddihy, Thom, Forde, Brian M., Chatfield, Mark D., Ling, Weiping, Mayer-Coverdale, Johanna, Norton, Robert and Harris, Patrick N.A. (2024). The molecular epidemiology of Burkholderia pseudomallei in North Queensland. Pathology Update 2024, Adelaide, VIC, Australia, 1 - 3 March 2024. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2023.12.133
Demir, Mervenur, Aslan, Abdullah Tarik, Seren Tanrıverdi, Elif, Otlu, Barış, Akova, Murat, Paterson, David, Harris, Patrick N. A. and Hazırolan, Gülşen (2023). Assessment of in vitro synergy between piperacillin-tazobactam-meropenem and imipenem-meropenem against OXA-48 producing Klebsiella pneumoniae using time-kill assays. IDWeek 2023, Boston, MA USA, 11-15 October 2023. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ofid/ofad500.2357
Stewart, Adam, Laupland, Kevin, Edwards, Felicity, Paterson, David and Harris, Patrick N. A. (2023). Elizabethkingia species: an emerging cause of healthcare-associated bloodstream infection among immunocompromised hosts. IDWeek 2023, Boston, MA USA, 11-15 October 2023. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ofid/ofad500.310
Peters, Nathan, Williamson, Frances, Bauer, Michelle, Llewellyn, Stacey, Snelling, Peter, Marsh, Nicole, Harris, Patrick, Stewart, Adam and Rickard, Claire (2023). A comparison of low-level to high-level disinfection in eliminating microorganisms from ultrasound transducers used on skin: a non-inferiority randomised controlled trial. 2023 ACIPC International Conference, Adelaide, SA Australia, 12-15 November 2023. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.idh.2023.09.002
Jung, Jeeyong and Harris, Patrick N.A. (2023). Proof of concept: artificial intelligence clustering of Burkholderia species according to antibiograms. Pathology Update 2023, Melbourne, VIC Australia, 24-26 February 2023. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2022.12.333
Ling, Weiping, Cadavid-Restrepo, Angela, Furuya-Kanamori, Luis, Harris, Patrick N.A. and Paterson, David L. (2023). Incidence and predictors of Escherichia coli–producing extended-spectrum beta-lactamase (ESBL-Ec) in Queensland, Australia, from 2010 to 2019: A population-based spatial analysis. 10th International Congress of the Asia Pacific Society of Infection Control 2022 (APSIC 2022), Singapore, 28 - 31 July 2022. Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/ash.2023.71
Langham, Freya, Tsai, Danny, Camilleri, Shayne, Forde, Brian, Harris, Patrick, Roberts, Jason A. and Chiong, Fabian (2022). Demographic, clinical and molecular epidemiology of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli bloodstream infections in Central Australia. 32nd International Congress of Antimicrobial Chemotherapy (ICC), Perth, WA Australia, 27-30 November 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1016/s2213-7165(22)00286-7
Gassiep, Ian, Bauer, Michelle J., Harris, Patrick N.A. and Norton, Robert (2022). Can mass spectrometry be used to identify burkholderia pseudomallei directly from spiked blood cultures?. Pathology Update 2022, Sydney, NSW Australia, 4-6 March 2022. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2021.12.274
Gassiep, Ian, Ganeshalingam, Vibooshini, Chatfield, Mark D., Harris, Patrick N.A. and Norton, Robert (2022). Burkholderia pseudomallei serology: Worth the hassle?. RCPA Quality Assurance Programs Presentations, Unknown, Unknown. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2021.12.276
Harris, Patrick N. A. (2021). Con) Piperacillin-tazobactam for ESBL-producing Enterobacterales. 13th International Symposium on Antimicrobial Agents and Resistance (ISAAR 2021), Online, 9-10 September 2021. Amsterdam, Netherlands: Elsevier . doi: 10.1016/j.ijantimicag.2021.106420.27
Gassiep, Ian, Bauer, Michelle J., Harris, Patrick N. A., Chatfield, Mark D. and Norton, Robert (2021). Laboratory safety: handling B. pseudomallei isolates without a biosafety cabinet. Pathology Update 2021, Online, 2-4 July 2021. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2021.06.105
Sumi, Chandra Datta, B.Sime, Fekade, Heffernan, Aaron J., Naicker, Saiyuri, Islam, Kamrul, Cottrell, Kyra, Harris, Patrick N.A. and Roberts, Jason A. (2020). Pharmacodynamic evaluation of intermittent versus prolonged infusion dosing regimens of piperacillin/tazobactam in a hollow-fiber infection model against two susceptible Klebsiella pneumoniae clinical isolates. Federation of Infection Societies Conference 2019, Edinburgh, United Kingdom, 11-14 November 2019. London, United Kingdom: The Microbiology Society. doi: 10.1099/acmi.fis2019.po0103
Stewart, Adam, Sarovich, Derek, Price, Erin, Burnard, Delaney, Harris, Patrick, Choong, Keat and Subedi, Shradha (2020). Molecular epidemiology and hospital spread of ceftriaxone non-susceptible enterobacterales in the Sunshine Coast region, Australia. RACP Congress 2020: Balancing medical science with humanity, Online, May 2020. Richmond, VIC Australia: Wiley-Blackwell. doi: 10.1111/imj.4_14846
Ayfan, A., Ertl, N., Whiley, D., Paterson, D., Heney, C., Harris, P., Macdonald, J., Irwin, A. and Zowawi, H. (2020). Rapid and sensitive molecular detection of antimicrobial resistance (AMR); towards point-of-care testing in low resource settings. GCCMID 2019, Dubai, United Arab Emirates, 6-9 November 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jiph.2020.01.059
Cuddihy, Thom, Forde, Brian, Rhodes, Nicholas, Paterson, David, Gorse, Dominique, Beatson, Scott and Harris, Patrick (2019). SRA down under: cache and analysis platform for infectious disease. Australian national conference for Health Informatics (HIC 2019), Melbourne, Australia, 12-14 August 2019. Amsterdam, Netherlands: IOS Press. doi: 10.3233/SHTI190776
Zowawi, H., Thomas, M., Abdelrahman, S., Shabban, M., Harris, P. and Paterson, D. (2019). Molecular Characterization of Multidrug-Resistant Gram-negative Bacilli in Egypt: A Snapshot Study. GCCMID 2018, Dubai, United Arab Emirates, 7-10 November 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jiph.2018.10.081
Roberts, Matthew, Scott, Susan, Harris, Patrick, Naber, Kurt, Wagenlehner, Florian and Doi, Suhail (2017). FOSFOMYCIN PROPHYLAXIS FOR TRANSRECTAL PROSTATE BIOPSY REDUCES INFECTIOUS COMPLICATIONS: A SYSTEMATIC REVIEW AND META-ANALYSIS. HOBOKEN: WILEY.
Ng, Oon Tek , Lee, Jia Jun , Harris, Patrick , Sidjabat, Hanna Evelina , Zowawi, Hosam , Shan Rajahram, Giri , Abdul Hameed, Ahneez Bt , Menon, Jayaram , Fong, Fennie Kah Ling , Hopkins, Katie , Wareham, David , Ho, Pak-Leung , Lo, Stephanie , Lau, Andes , Isozumi, Rie , Patel, Robin , Cunningham, Scott A. , Vasoo, Shawn , Kojic, Milan and Khong, Wei Xin (2017). Ability of blaNDM to disseminate worldwide into extensively drug-resistant bacterial hosts poses a major challenge to infection control and treatment: a global multi-centred whole-genome sequencing analysis. The 27th European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), Vienna Austria, 22-25 April 2017.
Harris, Patrick N. A., Zowawi, Hosam M., Banu, Shahera and Paterson, David L. (2016). Mapping the global prevalence of resistance to antimicrobials in gram-negative urinary pathogens: a meta-analysis of contemporary studies. The 55th Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC) / International Society of Chemotherapy (ISC)’s International Congress of Chemotherapy and Infection (ICC) - ICAAC/ICC, San Diego, CA, United States, 18-22 September 2016.
Harris, Patrick N. A., Wailan, Alexander, Buckley, Cameron, Catchpoole, Elizabeth, Zowawi, Hosam M., Whiley, David, Tshokey, Tshokey, Sharma, Ragunath, Chong, Smathi and Paterson, David L. (2016). Multi-drug Resistant Enterobacteriaceae from Bhutan: Whole Genome Sequencing of ESBL and Carbapenemase-producing Strains. International Congress for Tropical Medicine and Malaria (ICTMM 2016), Brisbane Australia, 18-22 September 2016.

Data Collections

Harris, Patrick N.A. (2017). Clinical meta-data from patients with bloodstream infections caused by 3GC-resistant E. coli. Harvard Dataverse. (Dataset)
Harris, Patrick N.A. (2017). Risk factors for relapse or persistence of bacteraemia caused by Enterobacter spp.: a case-control study. Harvard Dataverse. (Dataset)