My research interest is in the field of neuroimmunology, both in how the immune system causes disease of the nervous system, and more recently in how the immune system might contribute to recovery from damage. Much of my work in neuroimmunology has been done in the fields of MS and in neuromuscular disorders. In MS I have been interested in the regulation of inflammation. My interest in neuromuscular diseases led to studies of ALS, both in neurophysiology and in immunology. An overarching theme of my work has been an interest in how gender and pregnancy influence diseases of the nervous system.

Professor Pamela McCombe is a network member of the MND Collective at UQ.