Professor Pamela McCombe
Professor
UQ Centre for Clinical Research
+61 7 334 66017
My research interest is in the field of neuroimmunology, both in how the immune system causes disease of the nervous system, and more recently in how the immune system might contribute to recovery from damage. Much of my work in neuroimmunology has been done in the fields of MS and in neuromuscular disorders. In MS I have been interested in the regulation of inflammation. My interest in neuromuscular diseases led to studies of ALS, both in neurophysiology and in immunology. An overarching theme of my work has been an interest in how gender and pregnancy influence diseases of the nervous system.
Professor Pamela McCombe is a network member of the MND Collective at UQ.
Publications
Book
Pender, Michael P. and McCombe, Pamela A. Autoimmune neurological disease. Cambridge, United Kingdom: Cambridge University Press, 2009. doi:10.1017/cbo9780511526916
Book Chapters
Holdom, Cory J., Steyn, Frederik J., Henderson, Robert D., McCombe, Pamela A., Rogers, Mary-Louise and Ngo, Shyuan T. (2022). Biofluid biomarkers of amyotrophic lateral sclerosis. Neurodegenerative diseases biomarkers: towards translating research to clinical practice. (pp. 263-306) edited by Philip V. Peplow, Bridget Martinez and Thomas A. Gennarelli. New York, United States: Springer . doi: 10.1007/978-1-0716-1712-0_11
McCombe, Pamela A. and Greer, Judith M. (2019). Sexual dimorphism in the immune system. The autoimmune diseases. (pp. 419-428) edited by Noel R. Rose and Ian R. Mackay. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-812102-3.00024-5
Ngo, Shyuan T., Steyn, Frederik J., McCombe, Pamela A. and Borges, Karin (2015). High Caloric diets for amyotrophic lateral sclerosis. Bioactive nutraceuticals and dietary supplements in neurological and brain disease: prevention and therapy. (pp. 355-361) edited by Ronald Ross Watson and Victor R. Preedy. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-411462-3.00036-9
McCombe, Pamela A. and Greer, Judith M. (2014). Sexual dimorphism in the immune system. The Autoimmune Diseases. (pp. 319-328) edited by Ian R. Mackay and Noel R. Rose. San Diego, United States: Academic Press. doi: 10.1016/B978-0-12-384929-8.00024-1
Journal Articles
Lee, Aven, Henderson, Robert, Arachchige, Buddhika Jayakody, Robertson, Thomas and McCombe, Pamela Ann (2023). Proteomic investigation of ALS motor cortex identifies known and novel pathogenetic mechanisms. Journal of the Neurological Sciences, 452 120753, 120753. doi: 10.1016/j.jns.2023.120753
Howe, Stephanie L., Holdom, Cory J., McCombe, Pamela A., Henderson, Robert D., Zigman, Jeffrey M., Ngo, Shyuan T. and Steyn, Frederik J. (2023). Associations of postprandial ghrelin, liver‐expressed antimicrobial peptide 2 and leptin levels with body composition, disease progression and survival in patients with amyotrophic lateral sclerosis. European Journal of Neurology. doi: 10.1111/ene.16052
Diouf, Ibrahima, Malpas, Charles B, Sharmin, Sifat, Roos, Izanne, Horakova, Dana, Kubala Havrdova, Eva, Patti, Francesco, Shaygannejad, Vahid, Ozakbas, Serkan, Eichau, Sara, Onofrj, Marco, Lugaresi, Alessandra, Alroughani, Raed, Prat, Alexandre, Duquette, Pierre, Terzi, Murat, Boz, Cavit, Grand'Maison, Francois, Sola, Patrizia, Ferraro, Diana, Grammond, Pierre, Yamout, Bassem, Altintas, Ayse, Gerlach, Oliver, Lechner-Scott, Jeannette, Bergamaschi, Roberto, Karabudak, Rana, Iuliano, Gerardo, McGuigan, Christopher ... Kalincik, Tomas (2023). Effectiveness of multiple disease-modifying therapies in relapsing-remitting multiple sclerosis: causal inference to emulate a multiarm randomised trial. Journal of Neurology, Neurosurgery & Psychiatry, jnnp-2023. doi: 10.1136/jnnp-2023-331499
Sharmin, Sifat, Roos, Izanne, Simpson-Yap, Steve, Malpas, Charles, Sánchez, Marina M, Ozakbas, Serkan, Horakova, Dana, Havrdova, Eva K, Patti, Francesco, Alroughani, Raed, Izquierdo, Guillermo, Eichau, Sara, Boz, Cavit, Zakaria, Magd, Onofrj, Marco, Lugaresi, Alessandra, Weinstock-Guttman, Bianca, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Terzi, Murat, Amato, Maria Pia, Karabudak, Rana, Grand'Maison, Francois, Khoury, Samia J, Grammond, Pierre, Lechner-Scott, Jeannette, Buzzard, Katherine, Skibina, Olga ... Kalincik, Tomas (2023). The risk of secondary progressive multiple sclerosis is geographically determined but modifiable. Brain. doi: 10.1093/brain/awad218
Daruwalla, Cyrus, Shaygannejad, Vahid, Ozakbas, Serkan, Havrdova, Eva Kubala, Horakova, Dana, Alroughani, Raed, Boz, Cavit, Patti, Francesco, Onofrj, Marco, Lugaresi, Alessandra, Eichau, Sara, Girard, Marc, Prat, Alexandre, Duquette, Pierre, Yamout, Bassem, Khoury, Samia J., Sajedi, Seyed Aidin, Turkoglu, Recai, Altintas, Ayse, Skibina, Olga, Buzzard, Katherine, Grammond, Pierre, Karabudak, Rana, van der Walt, Anneke, Butzkueven, Helmut, Maimone, Davide, Lechner-Scott, Jeannette, Soysal, Aysun, John, Nevin ... Brown, J William L (2023). Early non-disabling relapses are important predictors of disability accumulation in people with relapsing-remitting multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England), 29 (7), 875-883. doi: 10.1177/13524585231151951
Kalincik, Tomas, Sharmin, Sifat, Roos, Izanne, Freedman, Mark S., Atkins, Harold, Burman, Joachim, Massey, Jennifer, Sutton, Ian, Withers, Barbara, Macdonell, Richard, Grigg, Andrew, Torkildsen, Øivind, Bo, Lars, Lehmann, Anne Kristine, Havrdova, Eva Kubala, Krasulova, Eva, Trněný, Marek, Kozak, Tomas, van der Walt, Anneke, Butzkueven, Helmut, McCombe, Pamela, Skibina, Olga, Lechner-Scott, Jeannette, Willekens, Barbara, Cartechini, Elisabetta, Ozakbas, Serkan, Alroughani, Raed, Kuhle, Jens, Patti, Francesco ... MSBase Study Group Authors (2023). Comparative effectiveness of autologous hematopoietic stem cell transplant vs fingolimod, natalizumab, and ocrelizumab in highly active relapsing-remitting multiple sclerosis. JAMA Neurology, 80 (7), 702-713. doi: 10.1001/jamaneurol.2023.1184
Harding-Forrester, Sam, Roos, Izanne, Nguyen, Ai-Lan, Malpas, Charles B, Diouf, Ibrahima, Moradi, Nahid, Sharmin, Sifat, Izquierdo, Guillermo, Eichau, Sara, Patti, Francesco, Horakova, Dana, Kubala Havrdova, Eva, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Grand'Maison, Francois, Onofrj, Marco, Lugaresi, Alessandra, Grammond, Pierre, Ozakbas,, Serkan, Amato, Maria Pia, Gerlach, Oliver, Sola, Patrizia, Ferraro, Diana, Buzzard, Katherine, Skibina, Olga, Lechner-Scott, Jeannette, Alroughani, Raed, Boz, Cavit ... Kalincik, Tomas (2023). Disability accrual in primary and secondary progressive multiple sclerosis. Journal of Neurology, Neurosurgery & Psychiatry, 94 (9) 330726, jnnp-2022. doi: 10.1136/jnnp-2022-330726
Tjokrowijoto, Priscilla, Phillips, Mia, Ceslis, Amelia, Henderson, Robert D., McCombe, Pamela A. and Robinson, Gail A. (2023). Sensitivity and specificity of the ECAS in identifying executive function and social cognition deficits in MND. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 24 (5-6), 466-474. doi: 10.1080/21678421.2023.2188053
Roos, Izanne, Diouf, Ibrahima, Sharmin, Sifat, Horakova, Dana, Havrdova, Eva Kubala, Patti, Francesco, Shaygannejad, Vahid, Ozakbas, Serkan, Izquierdo, Guillermo, Eichau, Sara, Onofrj, Marco, Lugaresi, Alessandra, Alroughani, Raed, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Terzi, Murat, Boz, Cavit, Grand’Maison, Francois, Sola, Patrizia, Ferraro, Diana, Grammond, Pierre, Turkoglu, Recai, Buzzard, Katherine, Skibina, Olga, Yamou, Bassem, Altintas, Ayse, Gerlach, Oliver, van Pesch, Vincent ... Kalincik, Tomas (2023). Comparative effectiveness in multiple sclerosis: a methodological comparison. Multiple Sclerosis Journal, 29 (3), 326-332. doi: 10.1177/13524585231151394
Katz, Matthew, Waddell, Leigh B., Yuen, Michaela, Bryen, Samantha J., Oates, Emily, Garton, Fleur C., Robertson, Thomas, Henderson, Robert David, Cooper, Sandra T. and McCombe, Pamela A. (2023). Case report: Adult-onset limb girdle muscular dystrophy in sibling pair due to novel homozygous LAMA2 missense variant. Frontiers in Neurology, 14 1055639. doi: 10.3389/fneur.2023.1055639
Noakes, Peter G., Phillips, William D., Jeffree, Rosalind L., Steyn, Frederik J., Wolvetang, Ernst J., Henderson, Rob D., McCombe, Pamela A. and Ngo, Shyuan T. (2023). Muscle and Its Neuromuscular Synapse – Players in the Pathogenesis of Motor Neuron Disease. Journal of Experimental Neurology, 4 (1), 1-5. doi: 10.33696/neurol.4.067
Yeow, Dennis, Katz, Matthew, Henderson, Robert, Prasad, Sandhir, Denman, Russell, Blum, Stefan, Davis, Mark, Robertson, Thomas and McCombe, Pamela (2023). Phenotypic variability within the desminopathies: A case series of three patients. Frontiers in Neurology, 13 1110934. doi: 10.3389/fneur.2022.1110934
Diouf, Ibrahima, Malpas, Charles B., Sharmin, Sifat, Roos, Izanne, Horakova, Dana, Havrdova, Eva Kubala, Patti, Francesco, Shaygannejad, Vahid, Ozakbas, Serkan, Izquierdo, Guillermo, Eichau, Sara, Onofrj, Marco, Lugaresi, Alessandra, Alroughani, Raed, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Terzi, Murat, Boz, Cavit, Grand'Maison, Francois, Hamdy, Sherif, Sola, Patrizia, Ferraro, Diana, Grammond, Pierre, Turkoglu, Recai, Buzzard, Katherine, Skibina, Olga, Yamout, Bassem, Altintas, Ayse ... Kalincik, Tomas (2023). Variability of the response to immunotherapy among subgroups of patients with multiple sclerosis. European Journal of Neurology, 30 (4), 1014-1024. doi: 10.1111/ene.15706
Signori, Alessio, Lorscheider, Johannes, Vukusic, Sandra, Trojano, Maria, Iaffaldano, Pietro, Hillert, Jan, Hyde, Robert, Pellegrini, Fabio, Magyari, Melinda, Koch-Henriksen, Nils, Sørensen, Per Soelberg, Spelman, Tim, van der Walt, Anneke, Horakova, Dana, Havrdova, Eva, Girard, Marc, Eichau, Sara, Grand'Maison, Francois, Gerlach, Oliver, Terzi, Murat, Ozakbas, Serkan, Skibina, Olga, Van Pesch, Vincent, Sa, Maria Jose, Prevost, Julie, Alroughani, Raed, McCombe, Pamela A, Gouider, Riadh, Mrabet, Saloua ... Butzkueven, Helmut (2023). Heterogeneity on long-term disability trajectories in patients with secondary progressive MS: a latent class analysis from Big MS Data network. Journal of Neurology, Neurosurgery and Psychiatry, 94 (1), 23-30. doi: 10.1136/jnnp-2022-329987
Nona, Robert J., Xu, Zhouwei, Robinson, Gail A., Henderson, Robert D. and McCombe, Pamela A. (2022). Age of onset and length of survival of Queensland patients with amyotrophic lateral sclerosis: with details of subjects with early onset and subjects with long survival. Neurodegenerative Diseases, 1-18. doi: 10.1159/000528875
McCombe, Pamela A., Hardy, Todd A., Nona, Robert J. and Greer, Judith M. (2022). Sex differences in Guillain Barré syndrome, chronic inflammatory demyelinating polyradiculoneuropathy and experimental autoimmune neuritis. Frontiers in Immunology, 13 1038411, 1-23. doi: 10.3389/fimmu.2022.1038411
Gillinder, Lisa, Papacostas, Jason, McCombe, Pamela and Chauvel, Patrick (2022). Effect of immunotherapy on intracranial EEG in patients with seronegative autoimmune-associated epilepsy. Epileptic Disorders, 24 (6), 1081-1086. doi: 10.1684/epd.2022.1488
Lefort, M., Sharmin, S., Andersen, J. B., Vukusic, S., Casey, R., Debouverie, M., Edan, G., Ciron, J., Ruet, A., De Sèze, J., Maillart, E., Zephir, H., Labauge, P., Defer, G., Lebrun-Frenay, C., Moreau, T., Berger, E., Clavelou, P., Pelletier, J., Stankoff, B., Gout, O., Thouvenot, E., Heinzlef, O., Al-Khedr, A., Bourre, B., Casez, O., Cabre, P., Montcuquet, A., Wahab, A. ... Leray, E. (2022). Impact of methodological choices in comparative effectiveness studies: application in natalizumab versus fingolimod comparison among patients with multiple sclerosis. BMC Medical Research Methodology, 22 (1) 155, 1-14. doi: 10.1186/s12874-022-01623-8
McCombe, Pamela A. and Greer, Judith M. (2022). Effects of biological sex and pregnancy in experimental autoimmune encephalomyelitis: It’s complicated. Frontiers in Immunology, 13 1059833, 1-24. doi: 10.3389/fimmu.2022.1059833
Cabrera-Serrano, Macarena, Caccavelli, Laure, Savarese, Marco, Vihola, Anna, Jokela, Manu, Johari, Mridul, Capiod, Thierry, Madrange, Marine, Bugiardini, Enrico, Brady, Stefen, Quinlivan, Rosaline, Merve, Ashirwad, Scalco, Renata, Hilton-Jones, David, Houlden, Henry, Aydin, Halil Ibrahim, Ceylaner, Serdar, Drewes, Sarah, Vockley, Jerry, Taylor, Rhonda L., Folland, Chiara, Kelly, Aasta, Goullee, Hayley, Ylikallio, Emil, Auranen, Mari, Tyynismaa, Henna, Udd, Bjarne, Forrest, Alistair R R, Davis, Mark R. ... Ravenscroft, Gianina (2022). Bi-allelic loss-of-function OBSCN variants predispose individuals to severe recurrent rhabdomyolysis. Brain, 145 (11), 3985-3998. doi: 10.1093/brain/awab484
Chang, Jeryn, Shaw, Thomas B., Holdom, Cory J., McCombe, Pamela A., Henderson, Robert D., Fripp, Jurgen, Barth, Markus, Guo, Christine C., Ngo, Shyuan T. and Steyn, Frederik J. (2022). Lower hypothalamic volume with lower BMI is associated with shorter survival in patients with ALS. European Journal of Neurology, 30 (1), 57-68. doi: 10.1111/ene.15589
Roos, Izanne, Malpas, Charles, Leray, Emmanuelle, Casey, Romain, Horakova, Dana, Havrdova, Eva Kubala, Debouverie, Marc, Patti, Francesco, De Seze, Jerome, Izquierdo, Guillermo, Eichau, Sara, Edan, Gilles, Prat, Alexandre, Girard, Marc, Ozakbas, Serkan, Grammond, Pierre, Zephir, Helene, Ciron, Jonathan, Maillart, Elisabeth, Moreau, Thibault, Amato, Maria Pia, Labauge, Pierre, Alroughani, Raed, Buzzard, Katherine, Skibina, Olga, Terzi, Murat, Laplaud, David Axel, Berger, Eric, Grand'maison, Francois ... Kalincik, Tomas (2022). Disease reactivation after cessation of disease-modifying therapy in patients with relapsing-remitting multiple sclerosis. Neurology, 99 (17), E1926-E1944. doi: 10.1212/WNL.0000000000201029
McDonald, Tanya S., Lerskiatiphanich, Titaya, Woodruff, Trent M., McCombe, Pamela A. and Lee, John D. (2022). Potential mechanisms to modify impaired glucose metabolism in neurodegenerative disorders. Journal of Cerebral Blood Flow and Metabolism, 43 (1), 26-43. doi: 10.1177/0271678x221135061
Vitkova, Marianna, Diouf, Ibrahima, Malpas, Charles, Horakova, Dana, Kubala Havrdova, Eva, Patti, Francesco, Ozakbas, Serkan, Izquierdo, Guillermo, Eichau, Sara, Shaygannejad, Vahid, Onofrj, Marco, Lugaresi, Alessandra, Alroughani, Raed, Prat, Alexandre, Larochelle, Catherine, Girard, Marc, Duquette, Pierre, Terzi, Murat, Boz, Cavit, Grand'maison, Francois, Sola, Patrizia, Ferraro, Diana, Grammond, Pierre, Butzkueven, Helmut, Buzzard, Katherine, Skibina, Olga, Yamout, Bassem I., Karabudak, Rana, Gerlach, Oliver ... Kalincik, Tomas (2022). Association of latitude and exposure to ultraviolet B radiation with severity of multiple sclerosis: An international registry study. Neurology, 98 (24), E2401-E2412. doi: 10.1212/WNL.0000000000200545
Sharmin, Sifat, Bovis, Francesca, Malpas, Charles, Horakova, Dana, Havrdova, Eva Kubala, Izquierdo, Guillermo, Eichau, Sara, Trojano, Maria, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Onofrj, Marco, Lugaresi, Alessandra, Grand'Maison, Francois, Grammond, Pierre, Sola, Patrizia, Ferraro, Diana, Terzi, Murat, Gerlach, Oliver, Alroughani, Raed, Boz, Cavit, Shaygannejad, Vahid, van Pesch, Vincent, Cartechini, Elisabetta, Kappos, Ludwig, Lechner-Scott, Jeannette, Bergamaschi, Roberto, Turkoglu, Recai, Solaro, Claudio ... Kalincik, Tomas (2022). Confirmed disability progression as a marker of permanent disability in multiple sclerosis. European Journal of Neurology, 29 (8), 2321-2334. doi: 10.1111/ene.15406
Lee, A., Klinkradt, S., McCombe, P. A. and Pow, D. V. (2022). Cloning of a new form of EAAT2/GLT-1 from human and rodent brains. Neuroscience Letters, 780 136637, 136637. doi: 10.1016/j.neulet.2022.136637
Nona, R. J., Greer, J. M., Henderson, R. D. and McCombe, P. A. (2022). HLA and amyotrophic lateral sclerosis: a systematic review and meta-analysis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 24 (1-2), 1-9. doi: 10.1080/21678421.2022.2078665
Ding, Qiao, Kesavan, Kaamini, Lee, Kah Meng, Wimberger, Elyse, Robertson, Thomas, Gill, Melinder, Power, Dominique, Chang, Jeryn, Fard, Atefeh T., Mar, Jessica C., Henderson, Robert D., Heggie, Susan, McCombe, Pamela A., Jeffree, Rosalind L., Colditz, Michael J., Hilliard, Massimo A., Ng, Dominic C. H., Steyn, Frederik J., Phillips, William D., Wolvetang, Ernst J., Ngo, Shyuan T. and Noakes, Peter G. (2022). Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease. Acta Neuropathologica Communications, 10 (1) 61, 61. doi: 10.1186/s40478-022-01360-5
Katz, Matthew, Garton, Fleur C., Davis, Mark, Henderson, Robert D. and McCombe, Pamela A. (2022). Novel variants of ANO5 in two patients with limb girdle muscular dystrophy: Case Report. Frontiers in Neurology, 13 868655, 868655. doi: 10.3389/fneur.2022.868655
McCombe, Pamela A. (2022). The role of sex and pregnancy in multiple sclerosis: what do we know and what should we do?. Expert Review of Neurotherapeutics, 22 (5), 377-392. doi: 10.1080/14737175.2022.2060079
Hop, Paul J., Zwamborn, Ramona A.J., Hannon, Eilis, Shireby, Gemma L., Nabais, Marta F., Walker, Emma M., van Rheenen, Wouter, van Vugt, Joke J.F.A., Dekker, Annelot M., Westeneng, Henk-Jan, Tazelaar, Gijs H.P., van Eijk, Kristel R., Moisse, Matthieu, Baird, Denis, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Ticozzi, Nicola, Ratti, Antonia, Cooper-Knock, Jonathan, Morrison, Karen E., Shaw, Pamela J., Basak, A. Nazli, Chiò, Adriano, Calvo, Andrea, Moglia, Cristina, Canosa, Antonio, Brunetti, Maura, Grassano, Maurizio, Gotkine, Marc ... Brain MEND Consortium (2022). Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Science Translational Medicine, 14 (633) eabj0264, 1-15. doi: 10.1126/scitranslmed.abj0264
Clarke, Laura, Bukhari, Wajih, O'Gorman, Cullen M., Khalilidehkordi, Elham, Arnett, Simon, Woodhall, Mark, Prain, Kerri M., Parratt, John D.E., Barnett, Michael H., Marriott, Mark P., McCombe, Pamela A., Sutton, Ian, Boggild, Mike, Brownlee, Wallace, Carroll, William M., Hodgkinson, Suzanne, Macdonell, Richard A.L., Mason, Deborah F., Pereira, Jennifer, Slee, Mark, Das, Chandi, Henderson, Andrew P.D., Kermode, Allan G., Lechner-Scott, Jeannette, Waters, Patrick, Sun, Jing and Broadley, Simon A. (2022). Response to treatment in NMOSD: the Australasian experience. Multiple Sclerosis and Related Disorders, 58 103408, 1-10. doi: 10.1016/j.msard.2021.103408
van Rheenen, Wouter, van der Spek, Rick A. A., Bakker, Mark K., van Vugt, Joke J. F. A., Hop, Paul J., Zwamborn, Ramona A. J., de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B., Deelen, Patrick, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu, Baird, Denis, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M., Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs H. P., van Eijk, Kristel R., Kooyman, Maarten, Byrne, Ross P., Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Ticozzi, Nicola ... SLAP Consortium (2022). Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nature Genetics, 54 (3), 361-361. doi: 10.1038/s41588-022-01020-3
Restuadi, Restuadi, Steyn, Frederik J., Kabashi, Edor, Ngo, Shyuan T., Cheng, Fei-Fei, Nabais, Marta F., Thompson, Mike J., Qi, Ting, Wu, Yang, Henders, Anjali K., Wallace, Leanne, Bye, Chris R., Turner, Bradley J., Ziser, Laura, Mathers, Susan, McCombe, Pamela A., Needham, Merrilee, Schultz, David, Kiernan, Matthew C., van Rheenen, Wouter, van den Berg, Leonard H., Veldink, Jan H., Ophoff, Roel, Gusev, Alexander, Zaitlen, Noah, McRae, Allan F., Henderson, Robert D., Wray, Naomi R., Giacomotto, Jean and Garton, Fleur C. (2022). Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1. Genome Medicine, 14 (1) 7, 7. doi: 10.1186/s13073-021-01006-6
van Rheenen, Wouter, van der Spek, Rick A. A., Bakker, Mark K., van Vugt, Joke J. F. A., Hop, Paul J., Zwamborn, Ramona A. J., de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B., Deelen, Patrick, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu, Baird, Denis, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M., Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs H. P., van Eijk, Kristel R., Kooyman, Maarten, Byrne, Ross P., Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Ticozzi, Nicola ... SLAP Consortium (2021). Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nature Genetics, 53 (12), 1636-1648. doi: 10.1038/s41588-021-00973-1
Holdom, Cory J., Janse van Mantgem, Mark R., van Eijk, Ruben P.A., Howe, Stephanie L., van den Berg, Leonard H., McCombe, Pamela A., Henderson, Robert D., Ngo, Shyuan T. and Steyn, Frederik J. (2021). Venous creatinine as a biomarker for loss of fat‐free mass and disease progression in patients with Amyotrophic Lateral Sclerosis. European Journal of Neurology, 28 (11) ene.15003, 3615-3625. doi: 10.1111/ene.15003
Henderson, Robert D., Agosti, Jan M., McCombe, Pamela A., Thorpe, Kathryn, Heggie, Susan, Heshmat, Saman, Appleby, Mark W., Ziegelaar, Brian W., Crowe, David T. and Redlich, Garry L. (2021). Phase 1b dose-escalation, safety, and pharmacokinetic study of IC14, a monoclonal antibody against CD14, for the treatment of amyotrophic lateral sclerosis. Medicine, 100 (42), e27421. doi: 10.1097/MD.0000000000027421
Maltby, Vicki E, Lea, Rodney A, Monif, Mastura, Fabis-Pedrini, Marzena J, Buzzard, Katherine, Kalincik, Tomas, Kermode, Allan G, Taylor, Bruce, Hodgkinson, Suzanne, McCombe, Pamela, Butzkueven, Helmut, Barnett, Michael and Lechner-Scott, Jeannette (2021). Efficacy of Cladribine Tablets as a Treatment for People With Multiple Sclerosis: Protocol for the CLOBAS Study (Cladribine, a Multicenter, Long-term Efficacy and Biomarker Australian Study). JMIR Research Protocols, 10 (10) e24969, e24969. doi: 10.2196/24969
Gillinder, Lisa, McCombe, Pamela, Powell, Tamara, Hartel, Gunter, Gillis, David, Rojas, Ingrid Leal and Radford, Kristen (2021). Cytokines as a marker of central nervous system autoantibody associated epilepsy. Epilepsy Research, 176 106708, 1-7. doi: 10.1016/j.eplepsyres.2021.106708
Holdom, Cory J., Ngo, Shyuan T., McCombe, Pamela A., Henderson, Robert D. and Steyn, Frederik J. (2021). Low plasma hyaluronan is associated with faster functional decline in patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (1-2), 1-7. doi: 10.1080/21678421.2021.1918721
Clarke, Laura, Arnett, Simon, Bukhari, Wajih, Khalilidehkordi, Elham, Jimenez Sanchez, Sofia, O'Gorman, Cullen, Sun, Jing, Prain, Kerri M., Woodhall, Mark, Silvestrini, Roger, Bundell, Christine S., Abernethy, David A., Bhuta, Sandeep, Blum, Stefan, Boggild, Mike, Boundy, Karyn, Brew, Bruce J., Brownlee, Wallace, Butzkueven, Helmut, Carroll, William M., Chen, Cella, Coulthard, Alan, Dale, Russell C., Das, Chandi, Fabis-Pedrini, Marzena J., Gillis, David, Hawke, Simon, Heard, Robert, Henderson, Andrew P. D. ... Broadley, Simon A. (2021). MRI patterns distinguish AQP4 antibody positive neuromyelitis optica spectrum disorder from multiple sclerosis. Frontiers in Neurology, 12 722237, 722237. doi: 10.3389/fneur.2021.722237
Sharmin, Sifat, Lefort, Mathilde, Andersen, Johanna Balslev, Leray, Emmanuelle, Horakova, Dana, Havrdova, Eva Kubala, Alroughani, Raed, Izquierdo, Guillermo, Ozakbas, Serkan, Patti, Francesco, Onofrj, Marco, Lugaresi, Alessandra, Terzi, Murat, Grammond, Pierre, Grand’Maison, Francois, Yamout, Bassem, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Boz, Cavit, Trojano, Maria, McCombe, Pamela, Slee, Mark, Lechner-Scott, Jeannette, Turkoglu, Recai, Sola, Patrizia, Ferraro, Diana, Granella, Franco, Prevost, Julie ... Kalincik, Tomas (2021). Natalizumab versus fingolimod in patients with relapsing-remitting multiple sclerosis: a subgroup analysis from three international cohorts. CNS Drugs, 35 (11), 1217-1232. doi: 10.1007/s40263-021-00860-7
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Lee, Aven, Arachchige, Buddhika Jayakody, Henderson, Robert, Aylward, James and McCombe, Pamela Ann (2021). Elevated levels of homocysteinesulfinic acid in the plasma of patients with amyotrophic lateral sclerosis: a potential source of excitotoxicity?. Neurodegenerative Diseases, 20 (5-6), 200-206. doi: 10.1159/000517964
Yeh, Wei Zhen, Widyastuti, Putu Ayu, Van der Walt, Anneke, Stankovich, Jim, Havrdova, Eva, Horakova, Dana, Vodehnalova, Karolina, Ozakbas, Serkan, Eichau, Sara, Duquette, Pierre, Kalincik, Tomas, Patti, Francesco, Boz, Cavit, Terzi, Murat, Yamout, Bassem I., Lechner-Scott, Jeannette, Sola, Patrizia, Skibina, Olga G., Barnett, Michael, Onofrj, Marco, Sá, Maria José, McCombe, Pamela Ann, Grammond, Pierre, Ampapa, Radek, Grand'Maison, Francois, Bergamaschi, Roberto, Spitaleri, Daniele L.A., Van Pesch, Vincent, Cartechini, Elisabetta ... Jokubaitis, Vilija G. (2021). Natalizumab, Fingolimod, and Dimethyl Fumarate use and pregnancy-related relapse and disability in women with multiple sclerosis. Neurology, 96 (24), E2989-E3002. doi: 10.1212/WNL.0000000000012084
Ishaq, Hira, Durrani, Talha, Umar, Zainab, Khan, Nemat, McCombe, Pamela and Ul Haq, Mian Ayaz (2021). Post-COVID opsoclonus myoclonus syndrome: a case report from Pakistan. Frontiers in Neurology, 12 672524, 672524. doi: 10.3389/fneur.2021.672524
Restuadi, Restuadi, Garton, Fleur C., Benyamin, Beben, Lin, Tian, Williams, Kelly L., Vinkhuyzen, Anna, van Rheenen, Wouter, Zhu, Zhihong, Laing, Nigel G., Mather, Karen A., Sachdev, Perminder S., Ngo, Shyuan T., Steyn, Frederik J., Wallace, Leanne, Henders, Anjali K., Visscher, Peter M., Needham, Merrilee, Mathers, Susan, Nicholson, Garth, Rowe, Dominic B., Henderson, Robert D., McCombe, Pamela A., Pamphlett, Roger, Blair, Ian P., Wray, Naomi R. and McRae, Allan F. (2021). Polygenic risk score analysis for amyotrophic lateral sclerosis leveraging cognitive performance, educational attainment and schizophrenia. European Journal of Human Genetics, 30 (5), 1-8. doi: 10.1038/s41431-021-00885-y
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Swayne, Andrew, Warren, Nicola, Prain, Kerri, Gillis, David, O'Gorman, Cullen, Tsang, Benjamin K-T., Muller, Claire, Broadley, Simon, Adam, Robert J., McCombe, Pamela, Wong, Richard C. and Blum, Stefan (2021). An Australian state-based cohort study of autoimmune encephalitis cases detailing clinical presentation, investigation results, and response to therapy. Frontiers in Neurology, 12 607773, 607773. doi: 10.3389/fneur.2021.607773
Kalincik, Tomas, Diouf, Ibrahima, Sharmin, Sifat, Malpas, Charles, Spelman, Tim, Horakova, Dana, Havrdova, Eva Kubala, Trojano, Maria, Izquierdo, Guillermo, Lugaresi, Alessandra, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Grammond, Pierre, Jokubaitis, Vilija, van der Walt, Anneke, Grand'Maison, Francois, Sola, Patrizia, Ferraro, Diana, Shaygannejad, Vahid, Alroughani, Raed, Hupperts, Raymond, Terzi, Murat, Boz, Cavit, Lechner-Scott, Jeannette, Pucci, Eugenio, Van Pesch, Vincent, Granella, Franco, Bergamaschi, Roberto ... Butzkueven, Helmut (2021). Effect of disease-modifying therapy on disability in relapsing-remitting multiple sclerosis over 15 years. Neurology, 96 (5), e783-e797. doi: 10.1212/WNL.0000000000011242
Bovis, Francesca, Kalincik, Tomas, Lublin, Fred, Cutter, Gary, Malpas, Charles, Horakova, Dana, Havrdova, Eva Kubala, Trojano, Maria, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Onofrj, Marco, Lugaresi, Alessandra, Izquierdo, Guillermo, Eichau, Sara, Patti, Francesco, Terzi, Murat, Grammond, Pierre, Bergamaschi, Roberto, Sola, Patrizia, Ferraro, Diana, Ozakbas, Serkan, Iuliano, Gerardo, Boz, Cavit, Hupperts, Raymond, Grand'Maison, Francois, Oreja-Guevara, Celia, van Pesch, Vincent, Cartechini, Elisabetta ... Sormani, Maria Pia (2021). Treatment response score to glatiramer acetate or interferon beta-1a. Neurology, 96 (2), e214-e227. doi: 10.1212/WNL.0000000000010991
Roos, Izanne, Leray, Emmanuelle, Frascoli, Federico, Casey, Romain, Brown, J William L, Horakova, Dana, Havrdova, Eva Kubala, Debouverie, Marc, Trojano, Maria, Patti, Francesco, Izquierdo, Guillermo, Eichau, Sara, Edan, Gilles, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Onofrj, Marco, Lugaresi, Alessandra, Grammond, Pierre, Ciron, Jonathan, Ruet, Aurélie, Ozakbas, Serkan, De Seze, Jérôme, Louapre, Céline, Zephir, Hélène, Sá, Maria José, Sola, Patrizia, Ferraro, Diana, Labauge, Pierre ... Kalincik, Tomas (2021). Determinants of therapeutic lag in multiple sclerosis. Multiple Sclerosis Journal, 27 (12), 1352458520981300-1851. doi: 10.1177/1352458520981300
Lee, John D., Heshmat, Saman, Heggie, Susan, Thorpe, Kathryn A., McCombe, Pamela A. and Henderson, Robert D. (2021). Clinical and electrophysiological examination of pinch strength in patients with amyotrophic lateral sclerosis. Muscle and Nerve, 63 (1) mus.27111, 108-113. doi: 10.1002/mus.27111
Zhong, Michael, van der Walt, Anneke, Stankovich, Jim, Kalincik, Tomas, Buzzard, Katherine, Skibina, Olga, Boz, Cavit, Hodgkinson, Suzanne, Slee, Mark, Lechner-Scott, Jeannette, Macdonell, Richard, Prevost, Julie, Kuhle, Jens, Laureys, Guy, Van Hijfte, Liesbeth, Alroughani, Raed, Kermode, Allan G, Butler, Ernest, Barnett, Michael, Eichau, Sara, van Pesch, Vincent, Grammond, Pierre, McCombe, Pamela, Karabudak, Rana, Duquette, Pierre, Girard, Marc, Taylor, Bruce, Yeh, Wei, Monif, Mastura ... Jokubaitis, Vilija G (2021). Prediction of multiple sclerosis outcomes when switching to ocrelizumab. Multiple Sclerosis Journal, 28 (6), 958-969. doi: 10.1177/13524585211049986
Hildebrand, Joanne M., Kauppi, Maria, Majewski, Ian J., Liu, Zikou, Cox, Allison J., Miyake, Sanae, Petrie, Emma J., Silk, Michael A., Li, Zhixiu, Tanzer, Maria C., Brumatti, Gabriela, Young, Samuel N., Hall, Cathrine, Garnish, Sarah E., Corbin, Jason, Stutz, Michael D., Di Rago, Ladina, Gangatirkar, Pradnya, Josefsson, Emma C., Rigbye, Kristin, Anderton, Holly, Rickard, James A., Tripaydonis, Anne, Sheridan, Julie, Scerri, Thomas S., Jackson, Victoria E., Czabotar, Peter E., Zhang, Jian-Guo, Varghese, Leila ... Silke, John (2020). A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction. Nature Communications, 11 (1) 3150, 3150. doi: 10.1038/s41467-020-16819-z
Lucia, Diana, McCombe, Pamela A., Henderson, Robert D. and Ngo, Shyuan T. (2020). Disorders of sleep and wakefulness in amyotrophic lateral sclerosis (ALS): a systematic review. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22 (3-4), 1-9. doi: 10.1080/21678421.2020.1844755
Ceslis, Amelia, Argall, Rosemary, Henderson, Robert D., McCombe, Pamela A. and Robinson, Gail A. (2020). The spectrum of language impairments in amyotrophic lateral sclerosis. Cortex, 132, 349-360. doi: 10.1016/j.cortex.2020.09.003
Lee, Aven, Arachchige, Buddhika Jayakody, Henderson, Robert, Pow, David, Reed, Sarah, Aylward, James and McCombe, Pamela Ann (2020). Elevated plasma levels of D-serine in some patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22 (3-4), 206-210. doi: 10.1080/21678421.2020.1832120
Iacoangeli, Alfredo, Lin, Tian, Al Khleifat, Ahmad, Jones, Ashley R., Opie-Martin, Sarah, Coleman, Jonathan R.I., Shatunov, Aleksey, Sproviero, William, Williams, Kelly L., Garton, Fleur, Restuadi, Restuadi, Henders, Anjali K., Mather, Karen A., Needham, Merilee, Mathers, Susan, Nicholson, Garth A., Rowe, Dominic B., Henderson, Robert, McCombe, Pamela A., Pamphlett, Roger, Blair, Ian P., Schultz, David, Sachdev, Perminder S., Newhouse, Stephen J., Proitsi, Petroula, Fogh, Isabella, Ngo, Shyuan T., Dobson, Richard J.B., Wray, Naomi R. ... Al-Chalabi, Ammar (2020). Genome-wide meta-analysis finds the ACSL5-ZDHHC6 locus is associated with ALS and links weight loss to the disease genetics. Cell Reports, 33 (4) 108323, 1-9. doi: 10.1016/j.celrep.2020.108323
Steyn, Frederik J., Li, Rui, Kirk, Siobhan E., Tefera, Tesfaye W, Xie, Teresa Y., Tracey, Timothy J., Kelk, Dean, Wimberger, Elyse, Garton, Fleur C., Roberts, Llion, Chapman, Sarah E., Coombes, Jeff S., Leevy, W. Matthew, Ferri, Alberto, Valle, Cristiana, René, Frédérique, Loeffler, Jean-Philippe, McCombe, Pamela A., Henderson, Robert D. and Ngo, Shyuan T. (2020). Altered skeletal muscle glucose-fatty acid flux in amyotrophic lateral sclerosis. Brain Communications, 2 (2) fcaa154, fcaa154. doi: 10.1093/braincomms/fcaa154
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McCombe, Pamela A., Garton, Fleur C., Katz, Matthew, Wray, Naomi R. and Henderson, Robert D. (2020). What do we know about the variability in survival of patients with amyotrophic lateral sclerosis?. Expert Review of Neurotherapeutics, 20 (9), 921-941. doi: 10.1080/14737175.2020.1785873
Yan, Jun, McCombe, Pamela A., Pender, Michael P. and Greer, Judith M. (2020). Reduced IκB-α protein levels in peripheral blood cells of patients with multiple sclerosis — a possible cause of constitutive NF-κB activation. Journal of Clinical Medicine, 9 (8) 2534, 2534-13. doi: 10.3390/jcm9082534
Alruwaili, Ashwag R., Pannek, Kerstin, Henderson, Robert D., Gray, Marcus, Kurniawan, Nyoman D. and McCombe, Pamela A. (2020). Serial MRI studies over 12 months using manual and atlas-based region of interest in patients with amyotrophic lateral sclerosis. BMC Medical Imaging, 20 (1) 90, 90. doi: 10.1186/s12880-020-00489-w
Oh, Jiwon, Achiron, Anat, Celius, Elisabeth G., Chambers, Christina, Derwenskus, Joy, Devonshire, Virginia, Hellwig, Kerstin, Hutton, George J., McCombe, Pamela, Moore, Marie, Rog, David, Schneider, Jean-Raphael, Simm, Renata Faria, Sousa, Livia, Vincent, Stephen G., Chung, Luke, Daizadeh, Nadia, Mitchell, Colin and Compston, D. Alastair S. (2020). Pregnancy outcomes and postpartum relapse rates in women with RRMS treated with alemtuzumab in the phase 2 and 3 clinical development program over 16 years. Multiple Sclerosis and Related Disorders, 43 102146, 102146. doi: 10.1016/j.msard.2020.102146
Kunchok, Amy, Lechner-Scott, Jeannette, Granella, Franco, Trojano, Maria, Alroughani, Raed, Sola, Patrizia, Ferraro, Diana, Lugaresi, Alessandra, Onofrj, Marco, Ozakbas, Serkan, Izquierdo, Guillermo, Grammond, Pierre, Luis Sanchez-Menoyo, Jose, Van Wijmeersch, Bart, Boz, Cavit, Pucci, Eugenio, McCombe, Pamela, Grand'Maison, Francois, Spitaleri, Daniele, Vucic, Steve, Hupperts, Raymond, Jokubaitis, Vilija, Sormani, Maria Pia, Butzkueven, Helmut and Kalincik, Tomas (2020). Prediction of on-treatment disability worsening in RRMS with the MAGNIMS score. Multiple Sclerosis Journal, 27 (5), 1352458520936823-705. doi: 10.1177/1352458520936823
Mohanty, Lipsa, Henderson, Robert D., McCombe, Pamela A. and Lee, Aven (2020). Levels of clusterin, CD5L, ficolin-3, and gelsolin in ALS patients and controls. Amyotrophic lateral sclerosis & frontotemporal degeneration, 21 (7-8), 1-4. doi: 10.1080/21678421.2020.1779303
Khalilidehkordi, Elham, Clarke, Laura, Arnett, Simon, Bukhari, Wajih, Jimenez Sanchez, Sofia, O'Gorman, Cullen, Sun, Jing, Prain, Kerri M., Woodhall, Mark, Silvestrini, Roger, Bundell, Christine S., Abernethy, David, Bhuta, Sandeep, Blum, Stefan, Boggild, Mike, Boundy, Karyn, Brew, Bruce J., Brown, Matthew, Brownlee, Wallace, Butzkueven, Helmut, Carroll, William M., Chen, Celia, Coulthard, Alan, Dale, Russell C., Das, Chandi, Fabis-Pedrini, Marzena J., Fulcher, David, Gillis, David, Hawke, Simon ... Broadley, Simon A. (2020). Relapse patterns in NMOSD: evidence for earlier occurrence of optic neuritis and possible seasonal variation. Frontiers in Neurology, 11 537, 537. doi: 10.3389/fneur.2020.00537
Katz, Matthew, Davis, Mark, Garton, Fleur C., Henderson, Robert, Bharti, Vanda, Wray, Naomi and McCombe, Pamela (2020). Mutations in heat shock protein beta-1 (HSPB1) are associated with a range of clinical phenotypes related to different patterns of motor neuron dysfunction: a case series. Journal of the Neurological Sciences, 413 116809, 116809. doi: 10.1016/j.jns.2020.116809
Lizak, Nathaniel, Hodgkinson, Suzanne, Butler, Ernest, Lechner-Scott, Jeannette, Slee, Mark, McCombe, Pamela Ann, Shaw, Cameron, Skibina, Olga, Vucic, Steve, Shuey, Neil, Barnett, Michael H, Parratt, John, Butzkueven, Helmut, Jack, Dominic, Fabris, Jessica and Kalincik, Tomas (2020). Real-world effectiveness of cladribine for Australian patients with multiple sclerosis: An MSBase registry substudy. Multiple Sclerosis Journal, 27 (3), 1352458520921087-474. doi: 10.1177/1352458520921087
Katz, Matthew, Walsh, Stephen, Tsang, Ben, Corbett, Joel, Sabet, Arman and McCombe, Pamela (2020). Takotsubo Cardiomyopathy in Myasthenic Crisis. Journal of Clinical Neuromuscular Disease, 21 (4), 244-245. doi: 10.1097/CND.0000000000000284
Malpas, Charles B., Manouchehrinia, Ali, Sharmin, Sifat, Roos, Izanne, Horakova, Dana, Havrdova, Eva Kubala, Trojano, Maria, Izquierdo, Guillermo, Eichau, Sara, Bergamaschi, Roberto, Sola, Patrizia, Ferraro, Diana, Lugaresi, Alessandra, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Grammond, Pierre, Grand'Maison, Francois, Ozakbas, Serkan, Van Pesch, Vincent, Granella, Franco, Hupperts, Raymond, Pucci, Eugenio, Boz, Cavit, Sidhom, Youssef, Gouider, Riadh, Spitaleri, Daniele, Soysal, Aysun, Petersen, Thor ... Kalincik, Tomas (2020). Early clinical markers of aggressive multiple sclerosis. Brain , 143 (5), 1400-1413. doi: 10.1093/brain/awaa081
McCombe, Pamela A., Lee, John D., Woodruff, Trent M. and Henderson, Robert D. (2020). The peripheral immune system and amyotrophic lateral sclerosis. Frontiers in Neurology, 11 279, 279. doi: 10.3389/fneur.2020.00279
McDonald, Tanya S., McCombe, Pamela A., Woodruff, Trent M. and Lee, John D. (2020). The potential interplay between energy metabolism and innate complement activation in amyotrophic lateral sclerosis. The FASEB Journal, 34 (6) fj.201901781, 7225-7233. doi: 10.1096/fj.201901781
Nabais, Marta F., Lin, Tian, Benyamin, Beben, Williams, Kelly L., Garton, Fleur C., Vinkhuyzen, Anna A. E., Zhang, Futao, Vallerga, Costanza L., Restuadi, Restuadi, Freydenzon, Anna, Zwamborn, Ramona A. J., Hop, Paul J., Robinson, Matthew R., Gratten, Jacob, Visscher, Peter M., Hannon, Eilis, Mill, Jonathan, Brown, Matthew A., Laing, Nigel G., Mather, Karen A., Sachdev, Perminder S., Ngo, Shyuan T., Steyn, Frederik J., Wallace, Leanne, Henders, Anjali K., Needham, Merrilee, Veldink, Jan H., Mathers, Susan, Nicholson, Garth ... Wray, Naomi R. (2020). Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. npj Genomic Medicine, 5 (1) 10, 1-9. doi: 10.1038/s41525-020-0118-3
Lee, Aven, Arachchige, Buddhika Jayakody, Reed, Sarah, Henderson, Robert, Aylward, James and McCombe, Pamela Ann (2020). Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levels. Journal of the Neurological Sciences, 409 116589, 116589. doi: 10.1016/j.jns.2019.116589
McGill, Raquel B., Steyn, Frederik J., Ngo, Shyuan T., Thorpe, Kathryn A., Heggie, Susan, Ruitenberg, Marc J., Henderson, Robert D., McCombe, Pamela A. and Woodruff, Trent M. (2020). Monocytes and neutrophils are associated with clinical features in amyotrophic lateral sclerosis. Brain Communications, 2 (1) fcaa013, fcaa013. doi: 10.1093/braincomms/fcaa013
Kunchok, Amy, Malpas, Charles, Nytrova, Petra, Havrdova, Eva Kubala, Alroughani, Raed, Terzi, Murat, Yamout, Bassem, Hor, Jyh Yung, Karabudak, Rana, Boz, Cavit, Ozakbas, Serkan, Olascoaga, Javier, Simo, Magdolna, Granella, Franco, Patti, Francesco, McCombe, Pamela, Csepany, Tunde, Singhal, Bhim, Bergamaschi, Roberto, Fragoso, Yara, Al-Harbi, Talal, Turkoglu, Recai, Lechner-Scott, Jeannette, Laureys, Guy, Oreja-Guevara, Celia, Pucci, Eugenio, Sola, Patrizia, Ferraro, Diana, Altintas, Ayse ... Kalincik, Tomas (2020). Clinical and therapeutic predictors of disease outcomes in AQP4-IgG+ neuromyelitis optica spectrum disorder. Multiple Sclerosis and Related Disorders, 38 101868, 1-8. doi: 10.1016/j.msard.2019.101868
Beecroft, Sarah J., Olive, Montse, Gonzalez Quereda, Lidia, Gallano, Pia, Ojanguren, Isabel, McLean, Catriona, McCombe, Pamela, Laing, Nigel G. and Ravenscroft, Gianina (2020). Cylindrical spirals in two families: clinical and genetic investigations. Neuromuscular Disorders, 30 (2), 151-158. doi: 10.1016/j.nmd.2019.12.006
Bukhari, Wajih, Clarke, Laura, O’Gorman, Cullen, Khalilidehkordi, Elham, Arnett, Simon, Prain, Kerri M., Woodhall, Mark, Silvestrini, Roger, Bundell, Christine S., Ramanathan, Sudarshini, Abernethy, David, Bhuta, Sandeep, Blum, Stefan, Boggild, Mike, Boundy, Karyn, Brew, Bruce J., Brownlee, Wallace, Butzkueven, Helmut, Carroll, William M., Chen, Celia, Coulthard, Alan, Dale, Russell C., Das, Chandi, Dear, Keith, Fabis-Pedrini, Marzena J., Fulcher, David, Gillis, David, Hawke, Simon, Heard, Robert ... Broadley, Simon A. (2020). The clinical profile of NMOSD in Australia and New Zealand. Journal of Neurology, 267 (5), 1431-1443. doi: 10.1007/s00415-020-09716-4
Lee, Aven, Balcar, Vladimir J., McCombe, Pamela and Pow, David V. (2020). Human brain neurons express a novel splice variant of excitatory amino acid transporter 5 (hEAAT5v). Journal of Comparative Neurology, 528 (17) cne.24907, 3134-3142. doi: 10.1002/cne.24907
Ngo, Shyuan T., Restuadi, Restuadi, McCrea, Allan F., Van Eijk, Ruben P., Garton, Fleur, Henderson, Robert D., Wray, Naomi R., McCombe, Pamela A. and Steyn, Frederik J. (2020). Progression and survival of patients with motor neuron disease relative to their fecal microbiota. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 21 (7-8), 1-14. doi: 10.1080/21678421.2020.1772825
Tea, Fiona, Lopez, Joseph A., Ramanathan, Sudarshini, Merheb, Vera, Lee, Fiona X. Z., Zou, Alicia, Pilli, Deepti, Patrick, Ellis, van der Walt, Anneke, Monif, Mastura, Tantsis, Esther M., Yiu, Eppie M., Vucic, Steve, Henderson, Andrew P. D., Fok, Anthony, Fraser, Clare L., Lechner-Scott, Jeanette, Reddel, Stephen W., Broadley, Simon, Barnett, Michael H., Brown, David A., Lunemann, Jan D., Dale, Russell C., Brilot, Fabienne, Sinclair, Adriane, Kermode, Allan G., Kornberg, Andrew, Bye, Annie, McGettigan, Benjamin ... Australasian and New Zealand MOG Study Group (2019). Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination. Acta Neuropathologica Communications, 7 (1) 145. doi: 10.1186/s40478-019-0786-3
Fambiatos, Adam, Jokubaitis, Vilija, Horakova, Dana, Havrdova, Eva Kubala, Trojano, Maria, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Lugaresi, Alessandra, Izquierdo, Guillermo, Grand'Maison, Francois, Grammond, Pierre, Sola, Patrizia, Ferraro, Diana, Alroughani, Raed, Terzi, Murat, Hupperts, Raymond, Boz, Cavit, Lechner-Scott, Jeannette, Pucci, Eugenio, Bergamaschi, Roberto, Van Pesch, Vincent, Ozakbas, Serkan, Granella, Franco, Turkoglu, Recai, Iuliano, Gerardo, Spitaleri, Daniele, McCombe, Pamela, Solaro, Claudio ... Kalincik, Tomas (2019). Risk of secondary progressive multiple sclerosis: A longitudinal study. Multiple Sclerosis Journal, 26 (1), 135245851986899-90. doi: 10.1177/1352458519868990
Chan, Fiona, Swayne, Andrew, Gillis, David, Walsh, Michael, Henderson, Robert D., McCombe, Pamela A., Wong, Richard C. and Blum, Stefan (2019). Long-term follow-up of patients with myasthenia gravis treated with low-dose rituximab. Journal of Neurology, Neurosurgery and Psychiatry, 90 (8), 1-2. doi: 10.1136/jnnp-2018-319410
Kerage, Daniel, Sloan, Erica K., Mattarollo, Stephen R. and McCombe, Pamela A. (2019). Interaction of neurotransmitters and neurochemicals with lymphocytes. Journal of Neuroimmunology, 332, 99-111. doi: 10.1016/j.jneuroim.2019.04.006
McCombe, Pamela A., Henderson, Robert D., Lee, Aven, Lee, John D., Woodruff, Trent M., Restuadi, Restuadi, McRae, Allan, Wray, Naomi R., Ngo, Shyuan and Steyn, Frederik J. (2019). Gut microbiota in ALS: possible role in pathogenesis?. Expert Review of Neurotherapeutics, 19 (9), 1-21. doi: 10.1080/14737175.2019.1623026
Ngo, Shyuan T., Van Eijk, Ruben P. A., Chachay, V. , Van Den Berg, Leonard H., Mccombe, Pamela A., Henderson, Robert D. and Steyn, Frederik J. (2019). Loss of appetite is associated with a loss of weight and fat mass in patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 20 (7-8), 1-9. doi: 10.1080/21678421.2019.1621346
McCombe, Pamela A. (2019). Women who contributed to past research in multiple sclerosis. Multiple Sclerosis Journal, 25 (11), 1352458519846101-1443. doi: 10.1177/1352458519846101
Mehta, Divya, Wani, Shivangi, Wallace, Leanne, Henders, Anjali K., Wray, Naomi R. and McCombe, Pamela A. (2019). Cumulative influence of parity-related genomic changes in multiple sclerosis. Journal of Neuroimmunology, 328, 38-49. doi: 10.1016/j.jneuroim.2018.12.004
Alruwaili, Ashwag R., Pannek, Kerstin, Henderson, Robert D., Gray, Marcus, Kurniawan, Nyoman D. and McCombe, Pamela A. (2019). Tract integrity in amyotrophic lateral sclerosis: 6–month evaluation using MR diffusion tensor imaging. BMC Medical Imaging, 19 (1) 19, 19. doi: 10.1186/s12880-019-0319-3
Nguyen, Ai-Lan, Havrdova, Eva Kubala, Horakova, Dana, Izquierdo, Guillermo, Kalincik, Tomas, van der Walt, Anneke, Terzi, Murat, Alroughani, Raed, Duquette, Pierre, Girard, Marc, Prat, Alexandre, Boz, Cavit, Sola, Patrizia, Ferraro, Diana, Lugaresi, Alessandra, Lechner-Scott, Jeannette, Barnett, Michael, Grand'Maison, Francois, Grammond, Pierre, Ramo-Tello, Cristina, Turkoglu, Recai, McCombe, Pamela, Pucci, Eugenio, Trojano, Maria, Granella, Franco, Spitaleri, Daniele, Van Pesch, Vincent, Soysal, Aysun, Oreja-Guevara, Celia ... Jokubaitis, Vilija (2019). Incidence of pregnancy and disease-modifying therapy exposure trends in women with multiple sclerosis: a contemporary cohort study. Multiple Sclerosis and Related Disorders, 28, 235-243. doi: 10.1016/j.msard.2019.01.003
Brown, J. William L., Coles, Alasdair, Horakova, Dana, Havrdova, Eva, Izquierdo, Guillermo, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Trojano, Maria, Lugaresi, Alessandra, Bergamaschi, Roberto, Grammond, Pierre, Alroughani, Raed, Hupperts, Raymond, McCombe, Pamela, Van Pesch, Vincent, Sola, Patrizia, Ferraro, Diana, Grand'Maison, Francois, Terzi, Murat, Lechner-Scott, Jeannette, Flechter, Schlomo, Slee, Mark, Shaygannejad, Vahid, Pucci, Eugenio, Granella, Franco, Jokubaitis, Vilija, Willis, Mark, Rice, Claire ... Robertson, Neil (2019). Association of initial disease-modifying therapy with later conversion to secondary progressive multiple sclerosis. JAMA - Journal of the American Medical Association, 321 (2), 175-187. doi: 10.1001/jama.2018.20588
Kalincik, Tomas, Kubala Havrdova, Eva, Horakova, Dana, Izquierdo, Guillermo, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Grammond, Pierre, Onofrj, Marco, Lugaresi, Alessandra, Ozakbas, Serkan, Kappos, Ludwig, Kuhle, Jens, Terzi, Murat, Lechner-Scott, Jeannette, Boz, Cavit, Grand'Maison, Francois, Prevost, Julie, Sola, Patrizia, Ferraro, Diana, Granella, Franco, Trojano, Maria, Bergamaschi, Roberto, Pucci, Eugenio, Turkoglu, Recai, McCombe, Pamela A, Pesch, Vincent Van, Van Wijmeersch, Bart, Solaro, Claudio ... Butzkueven, Helmut (2019). Comparison of fingolimod, dimethyl fumarate and teriflunomide for multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 90 (4), 458-468. doi: 10.1136/jnnp-2018-319831
McCombe, Pamela A. (2018). The short and long-term effects of pregnancy on multiple sclerosis and experimental autoimmune encephalomyelitis. Journal of Clinical Medicine, 7 (12) 494, 494. doi: 10.3390/jcm7120494
Hughes, Jordana, Jokubaitis, Vilija, Lugaresi, Alessandra, Hupperts, Raymond, Izquierdo, Guillermo, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Grand'maison, Francois, Grammond, Pierre, Sola, Patrizia, Ferraro, DIana, Ramo-Tello, Cristina, Trojano, Maria, Slee, Mark, Shaygannejad, Vahid, Boz, Cavit, Lechner-Scott, Jeanette, Van Pesch, Vincent, Pucci, Eugenio, Solaro, Claudio, Verheul, Freek, Terzi, Murat, Granella, Franco, Spitaleri, Daniele, Alroughani, Raed, Jun, Jae-Kwan, Fambiatos, Adam, Van Der Walt, Anneke ... Hinson, Eloise (2018). Association of inflammation and disability accrual in patients with progressive-onset multiple sclerosis. JAMA Neurology, 75 (11), 1407-1415. doi: 10.1001/jamaneurol.2018.2109
Blum, Stefan, Ji, Ying, Pennisi, David, Li, Zhixiu, Leo, Paul, McCombe, Pamela and Brown, Matthew A. (2018). Genome-wide association study in Guillain-Barré syndrome. Journal of Neuroimmunology, 323, 109-114. doi: 10.1016/j.jneuroim.2018.07.016
Yan, Jun, Winterford, Clay M., Catts, Vibeke S., Pat, Betty K., Pender, Michael P., McCombe, Pamela A. and Greer, Judith M. (2018). Increased constitutive activation of NF-κB p65 (RelA) in peripheral blood cells of patients with progressive multiple sclerosis. Journal of Neuroimmunology, 320, 111-116. doi: 10.1016/j.jneuroim.2018.04.002
Steyn, Frederik J., Ioannides, Zara A., van Eijk, Ruben P. A., Heggie, Susan, Thorpe, Kathryn A., Ceslis, Amelia, Heshmat, Saman, Henders, Anjali K., Wray, Naomi R., van den Berg, Leonard H., Henderson, Robert D., McCombe, Pamela A. and Ngo, Shyuan T. (2018). Hypermetabolism in ALS is associated with greater functional decline and shorter survival. Journal of Neurology, Neurosurgery, and Psychiatry, 89 (10), jnnp-2017. doi: 10.1136/jnnp-2017-317887
Alruwaili, A. R., Pannek, K., Coulthard, A., Henderson, R., Kurniawan, N. D. and McCombe, P. (2018). A combined tract-based spatial statistics and voxel-based morphometry study of the first MRI scan after diagnosis of amyotrophic lateral sclerosis with subgroup analysis. Journal of Neuroradiology, 45 (1), 41-48. doi: 10.1016/j.neurad.2017.03.007
Xu, Zhouwei, Lee, Aven, Nouwens, Amanda, David Henderson, Robert and Mccombe, Pamela Ann (2018). Mass spectrometry analysis of plasma from amyotrophic lateral sclerosis and control subjects. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 19 (5-6), 1-15. doi: 10.1080/21678421.2018.1433689
McCombe, Pamela A., Ngo, Shyuan T., Guo, Christine Cong, Fazlollahi, Amir, Bollmann, Saskia, Wang, Liting, Hu, Xintao, Barth, Markus, Salvado, Olivier, Davis, Mark, Ceslis, Amelia, Robinson, Gail, Henderson, Robert D. and Steyn, Frederik J. (2018). Patient with ALS with a novel TBK1 mutation, widespread brain involvement, behaviour changes and metabolic dysfunction. Journal of Neurology, Neurosurgery and Psychiatry, 90 (8), 952-954. doi: 10.1136/jnnp-2018-318823
Benyamin, Beben, He, Ji, Zhao, Qiongyi, Gratten, Jacob, Garton, Fleur, Leo, Paul J., Liu, Zhijun, Mangelsdorf, Marie, Al-Chalabi, Ammar, Anderson, Lisa, Butler, Timothy J., Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Devine, Matthew, Edson, Janette, Fifita, Jennifer A., Furlong, Sarah, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jeffree, Rosalind L., Jin, Zi-Bing, Li, Zhongshan, Li, Ting, Li, Mengmeng, Lin, Yong, Liu, Xiaolu ... Fan, Dongsheng (2017). Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Nature Communications, 8 (1) 611, 611. doi: 10.1038/s41467-017-00471-1
Lorscheider, Johannes, Jokubaitis, Vilija G., Spelman, Tim, Izquierdo, Guillermo, Lugaresi, Alessandra, Havrdova, Eva, Horakova, Dana, Trojano, Maria, Duquette, Pierre, Girard, Marc, Prat, Alexandre, Grand'Maison, Francois, Grammond, Pierre, Pucci, Eugenio, Boz, Cavit, Sola, Patrizia, Ferraro, Diana, Spitaleri, Daniele, Lechner-Scott, Jeanette, Terzi, Murat, Van Pesch, Vincent, Iuliano, Gerardo, Bergamaschi, Roberto, Ramo-Tello, Cristina, Granella, Franco, Oreja-Guevara, Celia, Butzkueven, Helmut, Kalincik, Tomas, MSBase Study Group and McCombe, Pamela A. (2017). Anti-inflammatory disease-modifying treatment and short-term disability progression in SPMS. Neurology, 89 (10), 1050-1059. doi: 10.1212/WNL.0000000000004330
Kalincik, Tomas, Manouchehrinia, Ali, Sobisek, Lukas, Jokubaitis, Vilija, Spelman, Tim, Horakova, Dana, Havrdova, Eva, Trojano, Maria, Izquierdo, Guillermo, Lugaresi, Alessandra, Girard, Marc, Prat, Alexandre, Duquette, Pierre, Grammond, Pierre, Sola, Patrizia, Hupperts, Raymond, Grand'Maison, Francois, Pucci, Eugenio, Boz, Cavit, Alroughani, Raed, Van Pesch, Vincent, Lechner-Scott, Jeannette, Terzi, Murat, Bergamaschi, Roberto, Iuliano, Gerardo, Granella, Franco, Spitaleri, Daniele, Shaygannejad, Vahid, Oreja-Guevara, Celia ... Butzkueven, Helmut (2017). Towards personalized therapy for multiple sclerosis: prediction of individual treatment response. Brain, 140 (9), 2426-2443. doi: 10.1093/brain/awx185
Kalincik, Tomas, Jokubaitis, Vilija, Spelman, Tim, Horakova, Dana, Havrdova, Eva, Trojano, Maria, Lechner-Scott, Jeannette, Lugaresi, Alessandra, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Grammond, Pierre, Solaro, Claudio, Grand'Maison, Francois, Hupperts, Raymond, Prevost, Julie, Sola, Patrizia, Ferraro, Diana, Terzi, Murat, Butler, Ernest, Slee, Mark, Kermode, Allan, Fabis-Pedrini, Marzena, McCombe, Pamela, Barnett, Michael, Shaw, Cameron, Hodgkinson, Suzanne, Butzkueven, Helmut and MSBase Study Group (2017). Cladribine versus fingolimod, natalizumab and interferon β for multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England), 24 (12), 1352458517728812-1626. doi: 10.1177/1352458517728812
Bukhari, Wajih, Prain, Kerri M., Waters, Patrick, Woodhall, Mark, O'Gorman, Cullen M., Clarke, Laura, Silvestrini, Roger A., Bundell, Christine S., Abernethy, David, Bhuta, Sandeep, Blum, Stefan, Boggild, Mike, Boundy, Karyn, Brew, Bruce J., Brown, Matthew, Brownlee, Wallace J., Butzkueven, Helmut, Carroll, William M., Chen, Celia, Coulthard, Alan, Dale, Russell C., Das, Chandi, Dear, Keith, Fabis-Pedrini, Marzena J., Fulcher, David, Gillis, David, Hawke, Simon, Heard, Robert, Henderson, Andrew P. D. ... Broadley, Simon A. (2017). Incidence and prevalence of NMOSD in Australia and New Zealand. Journal of Neurology Neurosurgery and Psychiatry, 88 (8), 632-638. doi: 10.1136/jnnp-2016-314839
Ngo, Shyuan T., Mi, Jia D., Henderson, Robert D., McCombe, Pamela A. and Steyn, Frederik J. (2017). Exploring targets and therapies for amyotrophic lateral sclerosis: current insights into dietary interventions. Degenerative Neurological and Neuromuscular Disease, 7, 95-108. doi: 10.2147/DNND.S120607
Garton, Fleur C., Benyamin, Beben, Zhao, Qiongyi, Liu, Zhijun, Gratten, Jacob, Henders, Anjali K., Zhang, Zong-Hong, Edson, Janette, Furlong, Sarah, Morgan, Sarah, Heggie, Susan, Thorpe, Kathryn, Pfluger, Casey, Mather, Karen A., Sachdev, Perminder S., McRae, Allan F., Robinson, Matthew R., Shah, Sonia, Visscher, Peter M., Mangelsdorf, Marie, Henderson, Robert D., Wray, Naomi R. and McCombe, Pamela A. (2017). Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort. Molecular Genetics and Genomic Medicine, 5 (4), 418-428. doi: 10.1002/mgg3.302
Ioannides, Z. A., Steyn, F. J., Henderson, R. D., McCombe, P. A. and Ngo, S. T. (2017). Predictions of resting energy expenditure in amyotrophic lateral sclerosis are greatly impacted by reductions in fat free mass. Cogent Medicine, 4 (1), 1343000. doi: 10.1080/2331205X.2017.1343000
McCombe, P. A., Wray, N. R. and Henderson, R. D. (2017). Extra-motor abnormalities in amyotrophic lateral sclerosis: another layer of heterogeneity. Expert Review of Neurotherapeutics, 17 (6), 561-577. doi: 10.1080/14737175.2017.1273772
Xu, Zhouwei, Alruwaili, Ashwag Rafea S., Henderson, Robert David and McCombe, Pamela Ann (2017). Screening for cognitive and behavioural impairment in amyotrophic lateral sclerosis: frequency of abnormality and effect on survival. Journal of the Neurological Sciences, 376, 16-23. doi: 10.1016/j.jns.2017.02.061
Kalincik, Tomas, Brown, J. William L., Robertson, Neil, Willis, Mark, Scolding, Neil, Rice, Claire M., Wilkins, Alastair, Pearson, Owen, Ziemssen, Tjalf, Hutchinson, Michael, McGuigan, Christopher, Jokubaitis, Vilija, Spelman, Tim, Horakova, Dana, Havrdova, Eva, Trojano, Maria, Izquierdo, Guillermo, Lugaresi, Alessandra, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Grammond, Pierre, Alroughani, Raed, Pucci, Eugenio, Sola, Patrizia, Hupperts, Raymond, Lechner-Scott, Jeannette, Terzi, Murat, Van Pesch, Vincent ... Grp, MSBase Study (2017). Treatment effectiveness of alemtuzumab compared with natalizumab, fingolimod, and interferon beta in relapsing-remitting multiple sclerosis: a cohort study. Lancet Neurology, 16 (4), 271-281. doi: 10.1016/S1474-4422(17)30007-8
Ioannides, Zara A., Steyn, Frederik J., Henderson, Robert D., Mccombe, Pamela A. and Ngo, Shyuan T. (2017). Anthropometric measures are not accurate predictors of fat mass in ALS. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 18 (7-8), 486-491. doi: 10.1080/21678421.2017.1317811
Henderson, Robert D. and McCombe, Pamela A. (2017). Assessment of motor units in neuromuscular disease. Neurotherapeutics, 14 (1), 69-77. doi: 10.1007/s13311-016-0473-z
Tao, Chunrong, Simpson, Steve, van der Mei, Ingrid, Blizzard, Leigh, Havrdova, Eva, Horakova, Dana, Shaygannejad, Vahid, Lugaresi, Alessandra, Izquierdo, Guillermo, Trojano, Maria, Duquette, Pierre, Girard, Marc, Grand'Maison, Franois, Grammond, Pierre, Alroughani, Raed, Terzi, Murat, Oreja-Guevara, Celia, Sajedi, Seyed Aidin, Iuliano, Gerardo, Sola, Patrizia, Lechner-Scott, Jeannette, Van Pesch, Vincent, Pucci, Eugenio, Bergamaschi, Roberto, Barnett, Michael, Ramo, Cristina, Singhal, Bhim, Spitaleri, Daniele L. A., Slee, Mark ... Taylor, Bruce V. (2016). Higher latitude is significantly associated with an earlier age of disease onset in multiple sclerosis. JNNP Online, 87 (12), 1343-1349. doi: 10.1136/jnnp-2016-314013
Xu, Zhouwei, Henderson, Robert David, David, Michael and McCombe, Pamela Ann (2016). Neurofilaments as biomarkers for amyotrophic lateral sclerosis: a systematic review and meta-analysis. PLoS ONE, 11 (10) e0164625, e0164625. doi: 10.1371/journal.pone.0164625
Lorscheider, Johannes, Buzzard, Katherine, Jokubaitis, Vilija, Spelman, Tim, Havrdova, Eva, Horakova, Dana, Trojano, Maria, Izquierdo, Guillermo, Girard, Marc, Duquette, Pierre, Prat, Alexandre, Lugaresi, Alessandra, Grand'maison, Francois, Grammond, Pierre, Hupperts, Raymond, Alroughani, Raed, Sola, Patrizia, Boz, Cavit, Pucci, Eugenio, Lechner-Scott, Jeanette, Bergamaschi, Roberto, Oreja-Guevara, Celia, Iuliano, Gerardo, Van Pesch, Vincent, Granella, Franco, Ramo-Tello, Cristina, Spitaleri, Daniele, Petersen, Thor, Slee, Mark ... Kalincik, Tomas (2016). Defining secondary progressive multiple sclerosis. Brain, 139 (9), 2395-2405. doi: 10.1093/brain/aww173
Ioannides, Z. A., Ngo, S. T., Henderson, R. D., McCombe, P. A. and Steyn, F. J. (2016). Altered metabolic homeostasis in amyotrophic lateral sclerosis: mechanisms of energy imbalance and contribution to disease progression. Neurodegenerative Diseases, 15 (5-6), 382-397. doi: 10.1159/000446502
Talman, Paul, Thi Duong, Vucic, Steve, Mathers, Susan, Venkatesh, Svetha, Henderson, Robert, Rowe, Dominic, Schultz, David, Edis, Robert, Needham, Merrilee, Macdonnell, Richard, McCombe, Pamela, Birks, Carol and Kiernan, Matthew (2016). Identification and outcomes of clinical phenotypes in amyotrophic lateral sclerosis/motor neuron disease: Australian National Motor Neuron Disease observational cohort. BMJ Open, 6 (9) e012054, e012054. doi: 10.1136/bmjopen-2016-012054
Jokubaitis, Vilija G., Spelman, Tim, Kalincik, Tomas, Lorscheider, Johannes, Havrdova, Eva, Horakova, Dana, Duquette, Pierre, Girard, Marc, Prat, Alexandre, Izquierdo, Guillermo, Grammond, Pierre, Van Pesch, Vincent, Pucci, Eugenio, Grand'Maison, Francois, Hupperts, Raymond, Granella, Franco, Sola, Patrizia, Bergamaschi, Roberto, Iuliano, Gerardo, Spitaleri, Daniele, Boz, Cavit, Hodgkinson, Suzanne, Olascoaga, Javier, Verheul, Freek, McCombe, Pamela, Petersen, Thor, Rozsa, Csilla, Lechner-Scott, Jeannette, Laura Saladino, Maria ... Trojano, Maria (2016). Predictors of long-term disability accrual in relapse-onset multiple sclerosis. Annals of Neurology, 80 (1), 89-100. doi: 10.1002/ana.24682
Yan, J., Greer, J. M. and McCombe, P. A. (2016). Interleukin 6 promoter 174 G/C polymorphisms in acute ischemic stroke: G allele is protective but not associated with IL-6 levels or stroke outcome. Journal of Neuroimmunology, 293, 22-27. doi: 10.1016/j.jneuroim.2016.02.001
Stewart, Tamasine, Spelman, Tim, Havrdova, Eva, Horakova, Dana, Trojano, Maria, Izquierdo, Guillermo, Duquette, Pierre, Girard, Marc, Prat, Alexandre, Lugaresi, Alessandra, Grand'Maison, Francois, Grammond, Pierre, Sola, Patrizia, Shaygannejad, Vahid, Hupperts, Raymond, Alroughani, Raed, Oreja-Guevara, Celia, Pucci, Eugenio, Boz, Cavit, Lechner-Scott, Jeannette, Bergamaschi, Roberto, Van Pesch, Vincent, Iuliano, Gerardo, Ramo, Cristina, Taylor, Bruce, Slee, Mark, Spitaleri, Daniele, Granella, Franco, Verheul, Freek ... Kalincik, Tomas (2016). Contribution of different relapse phenotypes to disability in multiple sclerosis. Multiple Sclerosis Journal, 23 (2), 266-276. doi: 10.1177/1352458516643392
McCombe, Pamela, Raj, Meenakshi, Henderson, Robert and Blum, Stefan (2016). A case series of patients with autoimmune myasthenia gravis in association with invasive thymoma. Journal of Clinical Neuromuscular Disease, 17 (3), 129-134. doi: 10.1097/CND.0000000000000101
Devine, Matthew S., Ballard, Emma, O'Rourke, Peter, Kiernan, Matther C., Mccombe, Pamela A. and Henderson, Robert D. (2015). Targeted assessment of lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 17 (3-4), 1-7. doi: 10.3109/21678421.2015.1125502
Ngo, S. T., Steyn, F. J., Huang, L., Mantovani, S., Pfluger, C. M. M., Woodruff, T. M., O'Sullivan, J. D., Henderson, R. D. and McCombe, P. A. (2015). Altered expression of metabolic proteins and adipokines in patients with amyotrophic lateral sclerosis. Journal of the Neurological Sciences, 357 (1-2), 22-27. doi: 10.1016/j.jns.2015.06.053
Chan, Adeline, Yan, Jun, Csurhes, Peter, Greer, Judith and McCombe, Pamela (2015). Circulating brain derived neurotrophic factor (BDNF) and frequency of BDNF positive T cells in peripheral blood in human ischemic stroke: effect on outcome. Journal of Neuroimmunology, 286, 42-47. doi: 10.1016/j.jneuroim.2015.06.013
Ioannides, Z. A., Henderson, R. D., Robertson, T., Davis, M. and McCombe, P. A. (2015). When does ALS start? A novel SOD-1 p.Gly142Arg mutation causing motor neurone disease with prominent premorbid cramps and spasms. Journal of Neurology, Neurosurgery and Psychiatry, 87 (9), 1031-1032. doi: 10.1136/jnnp-2015-311582
Broadley, Simon A., Barnett, Michael H., Boggild, Mike, Brew, Bruce J., Butzkueven, Helmut, Heard, Robert, Hodgkinson, Suzanne, Kermode, Allan G., Lechner-Scott, Jeannette, Macdonell, Richard A. L., Marriott, Mark, Mason, Deborah F., Parratt, John, Reddel, Stephen W., Shaw, Cameron P., Slee, Mark, Spies, Judith M., Taylor, Bruce V., Carroll, William M., Kilpatrick, Trevor J., King, John, McCombe, Pamela A., Pollard, John D. and Willoughby, Ernest (2015). A new era in the treatment of multiple sclerosis. Medical Journal of Australia, 203 (3), 139-141e.1. doi: 10.5694/mja14.01218
Blum, Stefan, Csurhes, Peter and McCombe, Pamela (2015). The frequencies of Killer immunoglobulin-like receptors and their HLA ligands in chronic inflammatory demyelinating polyradiculoneuropathy are similar to those in Guillian Barre syndrome but differ from those of controls, suggesting a role for NK cells in. Journal of Neuroimmunology, 285, 53-56. doi: 10.1016/j.jneuroim.2015.05.017
Blum, Stefan, Lee, David, Gillis, David, McEniery, David F., Reddel, Stephen and McCombe, Pamela (2015). Clinical features and impact of myasthenia gravis disease in Australian patients. Journal of Clinical Neuroscience, 22 (7), 1164-1169. doi: 10.1016/j.jocn.2015.01.022
McCombe, P. A., Pfluger, C., Singh, P., Lim, C. Y. H., Airey, C. and Henderson, R. D. (2015). Serial measurements of phosphorylated neurofilament-heavy in the serum of subjects with amyotrophic lateral sclerosis. Journal of the Neurological Sciences, 353 (1-2), 122-129. doi: 10.1016/j.jns.2015.04.032
Kalincik, Tomas, Horakova, Dana, Spelman, Tim, Jokubaitis, Vilija, Trojano, Maria, Lugaresi, Alessandra, Izquierdo, Guillermo, Rozsa, Csilla, Grammond, Pierre, Alroughani, Raed, Duquette, Pierre, Girard, Marc, Pucci, Eugenio, Lechner-Scott, Jeannette, Slee, Mark, Fernandez-Bolanos, Ricardo, Grand'Maison, Francois, Hupperts, Raymond, Verheul, Freek, Hodgkinson, Suzanne, Oreja-Guevara, Celia, Spitaleri, Daniele, Barnett, Michael, Terzi, Murat, Bergamaschi, Roberto, McCombe, Pamela, Sanchez-Menoyo, Jose, Simo Magdolna, Csepany, Tunde ... and on behalf of the MSBase Study Group (2015). Switch to natalizumab versus fingolimod in active relapsing-remitting multiple sclerosis. Annals of Neurology, 77 (3), 425-435. doi: 10.1002/ana.24339
McCombe, Pamela A. and Stenager, Egon (2015). Female infertility and multiple sclerosis: is this an issue?. Multiple Sclerosis Journal, 21 (1), 5-7. doi: 10.1177/1352458514549406
Devine, Matthew S., Pannek, Kerstin, Coulthard, Alan, McCombe, Pamela A., Rose, Stephen E. and Henderson, Robert D. (2015). Exposing asymmetric gray matter vulnerability in amyotrophic lateral sclerosis. NeuroImage: Clinical, 7, 782-787. doi: 10.1016/j.nicl.2015.03.006
Devine, Matthew S., Kiernan, Matthew C., Heggie, Susan, McCombe, Pamela A. and Henderson, Robert D. (2014). Study of motor asymmetry in ALS indicates an effect of limb dominance on onset and spread of weakness, and an important role for upper motor neurons. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 15 (7-8), 481-487. doi: 10.3109/21678421.2014.906617
Broadley, Simon A., Barnett, Michael H., Boggild, Mike, Brew, Bruce J., Butzkueven, Helmut, Heard, Robert, Hodgkinson, Suzanne, Kermode, Allan G. i, Lechner-Scott, Jeannette, Macdonell, Richard A. L., Marriott, Mark, Mason, Deborah F., Parratt, John, Reddel, Stephen W., Shaw, Cameron P., Slee, Mark, Spies, Judith, Taylor, Bruce V., Carroll, William M., Kilpatrick, Trevor J., King, John, McCombe, Pamela A., Pollard, John D. and Willoughby, Ernest (2014). Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: An Australian and New Zealand perspective Part 1 Historical and established therapies. Journal of Clinical Neuroscience, 21 (11), 1835-1846. doi: 10.1016/j.jocn.2014.01.016
Broadley, Simon A., Barnett, Michael H., Boggild, Mike, Brew, Bruce J., Butzkueven, Helmut, Heard, Robert, Hodgkinson, Suzanne, Kermode, Allan G., Lechner-Scott, Jeannette, Macdonell, Richard A. L., Marriott, Mark, Mason, Deborah F., Parratt, John, Reddel, Stephen W., Shaw, Cameron P., Slee, Mark, Spies, Judith, Taylor, Bruce V., Carroll, William M., Kilpatrick, Trevor J., King, John, McCombe, Pamela A., Pollard, John D. and Willoughby, Ernest (2014). Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: an Australian and New Zealand perspective - part 3: treatment practicalities and recommendations. Journal of Clinical Neuroscience, 21 (11), 1857-1865. doi: 10.1016/j.jocn.2014.01.017
Broadley, Simon A, Barnett, Michael H, Boggild, Mike, Brew, Bruce J, Butzkueven, Helmut, Heard, Robert, Hodgkinson, Suzanne, Kermode, Allan G, Lechner-Scott, Jeannette, Macdonell, Richard A L, Marriott, Mark, Mason, Deborah F, Parratt, John, Reddel, Stephen W, Shaw, Cameron P, Slee, Mark, Spies, Judith, Taylor, Bruce V, Carroll, William M, Kilpatrick, Trevor J, King, John, McCombe, Pamela A, Pollard, John D, Willoughby, Ernest and MS Neurology Group of the Australian and New Zealand Association of Neurologists (2014). Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: an Australian and New Zealand perspective: part 2 new and emerging therapies and their efficacy. MS Neurology Group of the Australian and New Zealand Association of Neurologists. Journal of Clinical Neuroscience, 21 (11), 1847-1856. doi: 10.1016/j.jocn.2014.01.018
McCombe, P. A. and Callaway, L. K. (2014). Multiparity in women with multiple sclerosis causes less long-term disability: No. Multiple Sclerosis Journal, 20 (11), 1435-1436. doi: 10.1177/1352458514541979
Mantovani, S., Gordon, R., Macmaw, J. K., Plfluger, C. M., Henderson, R. D., Noakes, P. G., McCombe, P. A. and Woodruff, T. M. (2014). Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient blood. Journal of Neuroimmunology, 276 (1-2), 213-218. doi: 10.1016/j.jneuroim.2014.09.005
Ngo, S. T., Steyn, F. J. and McCombe, P. A. (2014). Gender differences in autoimmune disease. Frontiers in Neuroendocrinology, 35 (3), 347-369. doi: 10.1016/j.yfrne.2014.04.004
Blum, Stefan and McCombe, Pamela A. (2014). Genetics of Guillain-Barre syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): current knowledge and future directions. Journal of the Peripheral Nervous System, 19 (2), 88-103. doi: 10.1111/jns5.12074
Ngo, S.T., Steyn, F.J. and McCombe, P.A. (2014). Body mass index and dietary intervention: Implications for prognosis of amyotrophic lateral sclerosis. Journal of the Neurological Sciences, 340 (1-2), 5-12. doi: 10.1016/j.jns.2014.02.035
Drovandi, Christopher C., Pettitt, Anthony N., Henderson, Robert D. and McCombe, Pamela A. (2014). Marginal reversible jump Markov chain Monte Carlo with application to motor unit number estimation. Computational Statistics and Data Analysis, 72, 128-146. doi: 10.1016/j.csda.2013.11.003
Yan, Jun, Liu, Jia, Greer, Judith M. and McCombe, Pamela A. (2014). Increased expression of the hypoxia-related genes in peripheral blood leukocytes of human subjects with acute ischemic stroke. Clinical and Experimental Neuroimmunology, 5 (2), 216-226. doi: 10.1111/cen3.12104
Blum, Stefan, Csurhes, Peter, Reddel, Stephen, Spies, Judy and McCombe, Pamela (2014). Killer immunoglobulin-like receptor and their HLA ligands in Guillain-Barré Syndrome. Journal of Neuroimmunology, 267 (1-2), 92-96. doi: 10.1016/j.jneuroim.2013.12.007
Liu, Jia, Yan, Jun, Greer, Judith M., Read, Stephen J., Henderson, Robert D., Rose, Stephen E., Coulthard, Alan and McCombe, Pamela A. (2014). Correlation of adrenomedullin gene expression in peripheral blood leukocytes with severity of ischemic stroke. International Journal of Neuroscience, 124 (4), 271-280. doi: 10.3109/00207454.2013.837462
Forrest, Kimberley, O'Rourke, Peter, McCombe, Pamela and Henderson, Robert (2014). Venous thromboembolism in amyotrophic lateral sclerosis: Should we consider routine prophylactic anticoagulation?. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16 (3-4), 280-281. doi: 10.3109/21678421.2014.984724
Steyn, F. J., Lee, Kevin, Fogarty, M. J., Veldhuis, J. D., McCombe, P. A,, Bellingham, M. C., Ngo, S. T. and Chen, C (2013). Growth hormone secretion is correlated with neuromuscular innervation rather than motor neuron number in early-symptomatic male amyotrophic lateral sclerosis mice. Endocrinology, 154 (12), 4695-4706. doi: 10.1210/en.2013-1570
Devine, Matthew S., Farrell, Anna, Woodhouse, Helen, McCombe, Pamela A. and Henderson, Robert D. (2013). A developmental perspective on bulbar involvement in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14 (7-8), 638-639. doi: 10.3109/21678421.2013.812663
Blum, Stefan, Reddel, Stephen, Spies, Judy and McCombe, Pamela (2013). Clinical features of patients with Guillain-Barre syndrome at seven hospitals on the east coast of Australia. Journal of The Peripheral Nervous System, 18 (4), 316-320. doi: 10.1111/jns5.12045
Yan, Jun, Catts, Vibeke S., Chan, Anthony and McCombe, Pamela A. (2013). A simple and reliable immunohistochemical method for colocalization of 2 antigens in the same cells of paraffin-embedded tissues. Applied Immunohistochemistry and Molecular Morphol, 21 (5), 471-477. doi: 10.1097/PAI.0b013e3182795710
Ioannides, Z. A., Airey, C., Fagermo, N., Blum, S., McCombe, P. A. and Henderson, R. J. (2013). Erratum: Susac syndrome and multifocal motor neuropathy first manifesting in pregnancy (Australian and New Zealand Journal of Obstetrics and Gynaecology (2013) 53 (314-317)). Australian and New Zealand Journal of Obstetrics and Gynaecology, 53 (4). doi: 10.1111/ajo.12121
Ioannides, Zara A., Airey, Caroline, Fagermo, Narelle, Blum, Stefan, McCombe, Pamela A. and Henderson, Robert J. (2013). Susac syndrome and multifocal motor neuropathy first manifesting in pregnancy. Australian and New Zealand Journal of Obstetrics and Gynaecology, 53 (3), 314-317. doi: 10.1111/ajo.12069
McCombe, Pamela A. and Greer, Judith M. (2013). Female reproductive issues in multiple sclerosis. Multiple Sclerosis Journal, 19 (4), 392-402. doi: 10.1177/1352458512452331
Devine, Matthew S., Woodhouse, Helen, McCombe, Pam A. and Henderson, Robert D. (2013). The relationship between limb dominance, disease lateralization and spread of weakness in amyotrophic lateral sclerosis (ALS). Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14 (2), 150-151. doi: 10.3109/17482968.2012.725416
Yan, Jun, Lin, Clement Y. H., Pfluger, Casey M. and McCombe, Pamela A. (2013). Levels of interleukin 33 and soluble suppression of tumorigenicity 2 in acute ischemic stroke. Clinical and Experimental Neuroimmunology, 4 (3), 339-347. doi: 10.1111/cen3.12067
Baumann, F., Henderson, R. D., Ridall, P. G., Pettitt, A. N. and McCombe, Pamela A. (2012). Use of Bayesian MUNE to show differing rate of loss of motor units in subgroups of ALS. Clinical Neurophysiology, 123 (12), 2446-2453. doi: 10.1016/j.clinph.2012.04.022
Inglis, Hayley R., Greer, Judith M. and McCombe, Pamela A. (2012). Gene expression in the spinal cord in female Lewis rats with experimental autoimmune encephalomyelitis induced with myelin basic proteins. PLoS One, 7 (11), e48555.1-e48555.15. doi: 10.1371/journal.pone.0048555
Cohen, Jeffrey A., Coles, Alasdair J., Arnold, Douglas L., Confavreux, Christian, Fox, Edward J., Hartung, Hans-Peter, Havrdova, Eva, Selmaj, Krzysztof W., Weiner, Howard L., Fisher, Elizabeth, Brinar, Vesna V., Giovannoni, Gavin, Stojanovic, Miroslav, Ertik, Bella I., Lake, Stephen L., Margolin, David H., Panzara, Michael A., Compston, D. Alastair S., CARE-MS I investigators and McCombe, Pamela (2012). Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial. Lancet, 380 (9856), 1819-1828. doi: 10.1016/S0140-6736(12)61769-3
Coles, Alasdair J., Twyman, Cary L., Arnold, Douglas L., Cohen, Jeffrey A., Confavreux, Christian, Fox, Edward J., Hartung, Hans-Peter, Havrdova, Eva, Selmaj, Krzysztof W., Weiner, Howard L., Miller, Tamara, Fisher, Elizabeth, Sandbrink, Rupert, Lake, Stephen L., Margolin, David H., Oyuela, Pedro, Panzara, Michael A., Compston, D. Alastair S., CARE-MS II investigators and McCombe, Pamela Ann (2012). Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial. Lancet, 380 (9856), 1829-1839. doi: 10.1016/S0140-6736(12)61768-1
Baumann, F., Henderson, R. D., Ridall, P. Gareth, Pettitt, A. N. and McCombe, Pamela A. (2012). Quantitative studies of lower motor neuron degeneration in amyotrophic lateral sclerosis: evidence for exponential decay of motor unit numbers and greatest rate of loss at the site of onset. Clinical Neurophysiology, 123 (10), 2092-2098. doi: 10.1016/j.clinph.2012.03.007
Ngo, S. T., Baumann, F., Ridall, P. G., Pettitt, A. N., Henderson, R. D., Bellingham, M. C. and McCombe, P. A. (2012). The relationship between Bayesian motor unit number estimation and histological measurements of motor neurons in wild-type and SOD1(G93A) mice. Clinical Neurophysiology, 123 (10), 2080-2091. doi: 10.1016/j.clinph.2012.01.028
Greer, Judith M. and McCombe, Pamela A. (2012). The role of epigenetic mechanisms and processes in autoimmune disorders. Biologics: Targets and Therapy, 6, 307-327. doi: 10.2147/BTT.S24067
Lin, C. Y., Pfluger, C. M., Henderson, R. D. and McCombe, P. A. (2012). Reduced levels of interleukin 33 and increased levels of soluble ST2 in subjects with amyotrophic lateral sclerosis. Journal of Neuroimmunology, 249 (1-2), 93-95. doi: 10.1016/j.jneuroim.2012.05.001
Rose, S., Rowland, T., Pannek, K., Baumann, F., Coulthard, A., McCombe, P. and Henderson, R. (2012). Structural hemispheric asymmetries in the human precentral gyrus hand representation. Neuroscience, 210, 211-221. doi: 10.1016/j.neuroscience.2012.02.044
Yan, Jun, Greer, Judith M. and McCombe, Pamela A. (2012). Prolonged elevation of cytokine levels after human acute ischaemic stroke with evidence of individual variability. Journal of Neuroimmunology, 246 (1-2), 78-84. doi: 10.1016/j.jneuroim.2012.02.013
Yan, Jun, Read, Stephen J., Henderson, Robert D., Hull, Renee, O'Sullivan, John D., McCombe, Pamela A. and Greer, Judith M. (2012). Frequency and function of regulatory T cells after ischaemic stroke in humans. Journal of Neuroimmunology, 243 (1-2), 89-94. doi: 10.1016/j.jneuroim.2011.12.019
Rose, Stephen, Pannek, Kerstin, Bell, Christopher, Baumann, Fusun, Hutchinson, Nicole, Coulthard, Alan, McCombe, Pamela and Henderson, Robert (2012). Direct evidence of intra- and interhemispheric corticomotor network degeneration in amyotrophic lateral sclerosis: An automated MRI structural connectivity study. NeuroImage, 59 (3), 2661-2669. doi: 10.1016/j.neuroimage.2011.08.054
Steyn, F. J., Ngo, S. T, Lee, J. D., Leong, J. W., Buckley, A. J., Veldhuis, J. D., McCombe, P. A., Chen, C. and Bellingham, M. C. (2012). Impairments to the GH-IGF-I axis in hSOD1(G93A) mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis. Endocrinology, 153 (8), 3735-3746. doi: 10.1210/en.2011-2171
Yan, Jun, Liu, Jia, Lin, Clement Yihao, Australia and New Zealand Multiple Sclerorsis Genetics Consortium, Csurhes, Peter A., Pender, Michael P., McCombe, Pamela A. and Greer, Judith M. (2012). Interleukin-6 Gene Promoter-572 C Allele may play a role in rate of disease progression in Multiple Sclerosis. International Journal of Molecular Sciences, 13 (10), 13667-13679. doi: 10.3390/ijms131013667
Blum, Stefan, Gillis, David, Brown, Helen, Boyle, Richard, Henderson, Robert, Heyworth-Smith, David, Hogan, Patrick, Kubler, Paul, Lander, Cecilie, Limberg, Nicole, Pillans, Peter, Prain, Kerri, Staples, Christopher, Walsh, Michael, McCombe, Pamela and Wong, Richard (2011). Use and monitoring of low dose rituximab in myasthenia gravis. Journal of Neurology, Neurosurgery and Psychiatry, 82 (6), 659-663. doi: 10.1136/jnnp.2010.220475
Hardy, Todd A., Blum, Stefan, McCombe, Pamela A. and Reddel, Stephen W. (2011). Guillain-Barré Syndrome: Modern theories of etiology. Current Allergy and Asthma Reports, 11 (3), 197-204. doi: 10.1007/s11882-011-0190-y
Greer, Judith M. and McCombe, Pamela A. (2011). Role of gender in multiple sclerosis: Clinical effects and potential molecular mechanisms. Journal of Neuroimmunology, 234 (1-2), 7-18. doi: 10.1016/j.jneuroim.2011.03.003
Singh, P., Yan, J., Hull, R., Read, S., O'Sullivan, J., Henderson, R.D., Rose, S., Greer, J.M. and McCombe, P.A. (2011). Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke. Journal of the Neurological Sciences, 304 (1-2), 117-121. doi: 10.1016/j.jns.2011.01.025
McCombe, P. A. and Henderson, R. D. (2011). The role of immune and inflammatory mechanisms in ALS. Current Molecular Medicine, 11 (3), 246-254. doi: 10.2174/156652411795243450
Blum, S., Robertson, T., Klingberg, S., Henderson, R.D. and McCombe, P. (2011). Atypical clinical presentations of the A3243G mutation, usually associated with MELAS. Internal Medicine Journal, 41 (2), 200-202. doi: 10.1111/j.1445-5994.2010.02379.x
McCombe, PA and Henderson, RD (2010). Effects of gender in amyotrophic lateral sclerosis. Gender Medicine, 7 (6), 557-570. doi: 10.1016/j.genm.2010.11.010
Baumann, Fusun, Rose, Stephen E., Nicholson, Garth A., Hutchinson, Nicole, Pannek, Kerstin, Pettitt, Anthony, McCombe, Pamela A. and Henderson, Robert D. (2010). Biomarkers of disease in a case of familial lower motor neuron ALS. Amyotrophic Lateral Sclerosis, 11 (5), 486-489. doi: 10.3109/17482961003774428
Baumann, Fusun, Henderson, Robert D., Tremayne, Fred, Hutchinson, Nicole and McCombe, Pamela A. (2010). Effects of prolonged repetitive stimulation of median, ulnar and peroneal nerves. Muscle & Nerve, 41 (6), 785-793. doi: 10.1002/mus.21604
McCombe, P. A. and Csurhes, P. A. (2010). T cells from patients with Guillain-Barre syndrome produce interferon-gamma in response to stimulation with the ganglioside GM1. Journal of Clinical Neuroscience, 17 (4), 537-538. doi: 10.1016/j.jocn.2009.07.096
Yan, Jun, Greer, Judith M., Hull, Renee, O'Sullivan, John D., Henderson, Robert D., Read, Stephen J. and McCombe, Pamela A. (2010). The effect of ageing on human lymphocyte subsets: comparison of males and females. Immunity & Ageing, 7 (4) 1742, 1-10. doi: 10.1186/1742-4933-7-4
Baumann, Fusan, Henderson, Robert D., Morrison, Stephen C., Brown, Michael, Hutchinson, N., Douglas, James A., Robinson, Peter J. and McCombe, Pamela A. (2010). Use of respiratory function tests to predict survival in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis, 11 (1-2), 194-202. doi: 10.3109/17482960902991773
Ridall, P. G., Pettitt, A. N., McCombe, P. A. and Henderson, R. D. (2009). Chapter 4 Bayesian analysis of the stimulus-response curve. Supplements to Clinical Neurophysiology, 60 (C), 47-56. doi: 10.1016/S1567-424X(08)00004-4
Henderson, R. D., Ridall, P. G., Pettitt, A. N. and McCombe, P. A. (2009). Chapter 5 Results of Bayesian statistical analysis in normal and ALS subjects. Supplements to Clinical Neurophysiology, 60 (C), 57-63. doi: 10.1016/S1567-424X(08)00005-6
McCombe, P.A., Greer, J.M. and Mackay, I.R. (2009). Sexual dimorphism in autoimmune disease. Current Molecular Medicine, 9 (9), 1058-1079. doi: 10.2174/156652409789839116
Henderson, Robert, Baumann, Fusun, Hutchinson, Nicole and McCombe, Pamela A. (2009). CMAP decrement in ALS. Muscle and Nerve, 39 (4), 555-556. doi: 10.1002/mus.21105
McCombe, Pamela A., Gordon TP and Jackson MW (2009). Bladder dysfunction in multiple sclerosis.. Expert Rev Neurother., 9 (3), 331-340. doi: 10.1586/14737175.9.3.331
Yan, Jun, Greer, Judith M., Etherington, Kellie, Cadigan, Greg P., Cavanagh, Helen, Henderson, Robert D., O'Sullivan, John D., Pandian, Jeyaraj D., Read, Stephen J. and McCombe, Pamela A. (2009). Immune activation in the peripheral blood of patients with acute ischemic stroke. Journal of Neuroimmunology, 206 (1-2), 112-117. doi: 10.1016/j.jneuroim.2008.11.001
McCombe, P. A. (2008). Recombinant EPF/chaperonin 10 promotes the survival of O4-positive pro-oligodendrocytes prepared from neonatal rat brain. Cell Stress & Chaperones, 13 (4), 467-474. doi: 10.1007/s12192-008-0045-1
McCombe, Pamela A. and Read, Stephen J. (2008). Immune and inflammatory responses to stroke: Good or bad?. International Journal of Stroke, 3 (4), 254-265. doi: 10.1111/j.1747-4949.2008.00222.x
Jackson, Michael W., Gordon, Thomas P. and McCombe, Pamela A. (2008). Autoantibody-mediated bowel and bladder dysfunction in a patient with chronic, nondiabetic neuropathy. Muscle and Nerve, 37 (4), 537-543. doi: 10.1002/mus.20946
McCombe, Pamela A. (2008). Symptom management and patient issues. Focus on Multiple Sclerosis, 3 (1), 4-6.
Skene, L., Kerridge, I., Marshall, B. and McCombe, Pamela A. (2008). The Lockhart Committee: Developing policy through commitment to moral values, community and democratic processes. Journal of Law & Medicine, 16 (1), 132-138.
Harness, J. and McCombe, Pamela A. (2008). Increased levels of activated T-cells and reduced levels of CD4/CD25+ cells in peripheral blood of Guillain-Barre syndrome patients compared to controls. Journal of Clinical Neuroscience, 15 (9), 1031--1035. doi: 10.1016/j.jocn.2007.09.016
Henderson, R. D., Ridall, P. G., Hutchinson, N. M., Pettitt, A. N. and McCombe, P. A. (2007). Bayesian statistical MUNE method. Muscle & Nerve, 36 (2), 206-213. doi: 10.1002/mus.20805
Ridall, P. G., Pettitt, A. N., Friel, N., McCombe, P. A. and Henderson, R. D. (2007). Motor unit number estimation using reversible jump Markov chain Monte Carlo methods. Journal of the Royal Statistical Society, 56 (3), 235-269. doi: 10.1111/j.1467-9876.2007.00576.x
Inglis, H. R., Csurhes, P. A. and McCombe, P. A. (2007). Antibody responses to peptides of peripheral nerve myelin proteins P0 and P2 in patients with inflammatory demyelinating neuropathy. Journal of Neurology, Neurosurgery & Psychiatry, 78 (4), 419-422. doi: 10.1136/jnnp.2006.106617
Pandian, J. D., Dalton, K., Henderson, R. D. and McCombe, P. A. (2007). Postural orthostatic tachycardia syndrome: an underrecognized disorder. Internal Medicine Journal, 37 (8), 529-535. doi: 10.1111/j.1445-5995.2007.01356.x
Ridall, P. Gareth, Pettitt, Anthony N., Henderson, Robert D. and McCombe, Pamela A. (2006). Motor unit number estimation - A Bayesian approach. Biometrics, 62 (4), 1235-1250. doi: 10.1111/j.1541-0420.2006.00577.x