Researcher biography

I am a Postdoctoral Researcher in Prof Paul Colditz's research group at UQCCR. My research focuses on inflammation in the neonatal brain following hypoxic-ischemic (HI) events. Preterm birth, intrauterine growth restriction and HI brain injury are major contributors to mortality and long-term morbidity in the neonate. Currently there are no pharmacological interventions available that significantly alleviate brain injury in the neonate. My research aims to better understand the mechanisms of neuronal injury, which is critical for the identification of potential targets and development of improved treatment options for babies who develop brain damage through HI insults, growth restriction or premature birth; the leading causes of cerebral palsy (CP). Mounting evidence suggests that inflammation is a major contributor to neuronal injury. Inflammation encompasses a number of processes including increased numbers of activated microglia and elevated levels of proinflammatory cytokines. My research focuses on examining key inflammatory mediators each with the potential to be critical for HI-induced effects on neuronal networks. Developing therapies that reduce inflammation offer an alternative pathway to neuroprotection and preventing outcomes such as CP.