Microbial diagnostics and characterisation

About

Associate Professor David Whiley manages the Microbial Diagnostics and Characterisation Lab, which is a joint initiative of Pathology Queensland and The University of Queensland’s Centre for Clinical Research (UQCCR). This Lab focuses on enhancing the capacity of clinical laboratories to diagnose, identify, and characterise bacteria and viruses, with an emphasis on paediatric, respiratory, and sexually transmitted infections. 

The Lab’s priority research area is antimicrobial-resistance, with the aim to improve antibiotic-resistance surveillance in areas where current surveillance activities are limited. We currently hold an Australian Research Council ITRP Research Hub on this topic, encompassing gonorrhoea, mycoplasma, CMV, and more.

We are currently recruiting Honours, Masters, and PhD students to work on many of the exciting and cutting-edge projects listed under the Research Projects tab, below. Any enthusiastic, research-minded students can email our Senior Group Members or Group Leader for more information.

Contact

+61 7 3346 5555

d.whiley@uq.edu.au

Whiley group

 

Group Leader

Postdoctorals

Students

Support staff

  • Identifying novel and discriminatory markers for invasive Aspergillus fumigatus infection for diagnostic application in immunocompromised patients
  • Mycoplasma genitalium antimicrobial resistance diagnostics
  • Novel approaches for the detection and characterisation of Mycoplasma genitalium
  • Isothermal detection methods for ceftriaxone-resistant gonorrhoea
  • Molecular characterisation of syphilis in Queensland
  • Enhanced molecular diagnostics for cytomegalovirus in children undergoing hematopoietic stem cell transplant
  • Enhanced diagnosis and management of active human herpesvirus-6 infections in immunocompromised children
  • Rapid detection of M1UK Group A Streptococcus
  • Molecular detection of meningococcal antimicrobial resistance
  • Neisseria gonorrhoeae molecular antimicrobial susceptibility assay utility: generating evidence to inform gonorrhoea management strategies
  • Rapid whole genome sequencing protocols for SARS-CoV-2 infections
  • Using genetic surveillance to understand the disrupted seasonality of paediatric respiratory viruses despite physical distancing
  • Development of wastewater-based epidemiology as a complementary approach for infectious disease surveillance
  • Epidemiological surveillance of Neisseria gonorrhoeae AMR in Indonesia
  • Prevalence of ocular Chlamydia trachomatis infection and anti-Pgp3 antibodies in Nauru and Choiseul
  • Epidemiological surveillance of Neisseria gonorrhoeae AMR in Fiji

Australian

  • Dr Brian Forde, The University of Queensland
  • Dr Chris Howard, The University of Queensland
  • Dr Krispin Hajkowicz, The University of Queensland
  • Professor Amy Jennison, Queensland Health
  • Professor Stephen Lambert, Queensland Government
  • Professor Robert Ware, Menzies Health Institute Queensland, Griffith University
  • Professor Monica Lahra, World Health Organisation Collaborating Centre for STI and AMR, New South Wales Health Pathology

International

  • Associate Professor Katherine Rhodes, University of Arizona, USA
  • Professor Andreas Meinhardt, Justus Liebig University Giessen, Germany
  • Professor Hans-Christian Schuppe, Justus Liebig University Giessen, Germany
  • Dr Daniela Fietz, Justus Liebig University Giessen, Germany

Current

  • 2025 - Children’s Hospital Foundation: Enhanced diagnosis and management of active human herpesvirus-6 infections in immunocompromised children
  • 2025 - Australian Research Council: ARC ITRP Research Hub to Combat Antimicrobial Resistance
  • 2023 - HeIDI and CSIRO IDR and AMR Mission Affiliated Projects: Development of Wastewater-based epidemiology as a complementary approach for infectious disease surveillance
  • 2023 – UQ/Australian Infectious Diseases Research Centre Basic-Clinical Seed Funding: Identifying novel and discriminatory markers for invasive Aspergillus fumigatus infection for diagnostic application in immunocompromised patients
  • 2023 – UQ/Australian Infectious Diseases Research Centre Basic-Clinical Seed Funding: Development of a prototype isothermal detection method for ceftriaxone-resistant gonorrhoea

Recently completed

  • 2023 - SpeeDx: REDI Fellowship on development of diagnostics for Mycoplasma genitalium
  • 2023 - Children’s Hospital Foundation: The development of an integrated molecular diagnostic pathway to optimise the treatment of cytomegalovirus in children undergoing haematopoietic stem cell transplant
  • 2022 – FSS Research and Development Grant
  • 2022 – Sexual Health Research Fund: Expanded gonorrhoea screening to inform guidelines for asymptomatic heterosexual women and men
  • 2022 – UQ Seed Funding: Exploring the association between oral HPV and pharyngeal STIs (QIMR collaboration)
  • 2022 - Australian Society for HIV, Viral Hepatitis and Sexual Health Medicine: Precision public health for enhanced syphilis management in Queensland
  • 2022 - DMTC: Refining a molecular genetics platform for rapid and accurate point-of-care detection of pathogens
  • 2022 - SpeeDx: ResistancePlus MABSC/MAC test for detection of MABSC, MAC and gene markers associated with susceptibility or resistance to macrolides and amikacin antibiotics
  • 2022 – Pathology Queensland Study, Education & Research Trust Fund: Rapid Whole Genome Sequencing Protocols for SARS-CoV-2 Infections
  • 2021 - Children’s Hospital Foundation: Enhancing detectioin and management of Mycobacterium abscessus complex (MABSC) infection in children with cystic fibrosis
  • 2020 - Children’s Hospital Foundation: Rapid point-of-care tests for multidrug resistant superbugs
  • 2020 - UQ Early Career Project-Support Grant: Preparing for the worst: novel rapid diagnostics for extensively drug resistant (XDR) Salmonella in high and low resource settings
  • 2020 - Pathology Queensland Study, Education & Research Trust Fund: Enhanced diagnostic testing for Mycoplasma genitalium antibiotic resistance

Whiley lab